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The map label for this gene is 37521415

Identifier: 37521415

GI number: 37521415

Start: 1965528

End: 1966703

Strand: Reverse

Name: 37521415

Synonym: gll1846

Alternate gene names: NA

Gene position: 1966703-1965528 (Counterclockwise)

Preceding gene: 37521416

Following gene: 37521414

Centisome position: 42.21

GC content: 66.41

Gene sequence:

>1176_bases
GTGGCCGATCGGGTGGAGGTGCCGACATTCATCCAGATGCGCGAGGCGAATTGGCGCTTCGGCTTTAAATTGCTCAGTCT
GATCAACGAAGCGCCCCTGCGGGCGAATCGGGAGCGCTCCCCGCTCGCGGTCGAACGCAACGTACTCCTTTCACCCCTGG
GGTTGGGGATCACCCTGGGCCGGCTGCTGCCCAGTTTGTCCGAGACCGCGCAGCGGGCGGTGGCCAGTTCCCTCGAATGG
CCCAACGACGGGTTGATCGAGCCGCAGTCGGCGACGGCGCTACTGGCCGCCCAGTTGACGGGGGCCGATCCCCAGGTGCA
GCCGGTGCACGCCGGATTGTACTGGGTGGAGCCGGGCACGCCCGTGAAGCTGGGACGGGATCTCAGCGGCAACCGGGTGC
TGGAGAGCGCTTTTCAAGACGGAGCGGCTCCCCCCGAAATCAACCGCTGGATCGCCGCCGCCACCGGCGGCCAGATTGGC
GAAGCGCTCATCCCCGGCCCCCGCCGGCCTGGCCCGCTGGTGGTGGTCGATGCGACCGTCTTCGAAGGGATCTGGAGTCG
GGCTTTTAACCCCCAGAGCAGTCTCCAGGCTCCTTTCACCCTCCTGGACGGCAAGCAGACAACTGTCTGGCAGATGAGCC
GGACGGGCAGTTTTCGCTACTACGAGACTCCTGGTTTTCAGGCGGTCCAGTTGCCCTTCGGCGGCGACGGCGAGTGGAGC
ATGGCGGTGTTTGTGCCCGCGGCCGGGGTGCCTTTGCGGTCGTTTGTGCGCAACTTGAGCGACGAGAAATGGCGTCTGTG
GTTCGAGCAATTTCGGATGCGCGACGGGAGCGTGACCCTTCCTCGCCTGCGCCTGCGCTACGGCCAGGATTTGCGCCGGG
CGCTTCGAGCCCTCGGGATGCGGTCCGCCTTTACCCGCTCGGAGGGCGAGGAGAGCCTCGGTGAAGCGGGGTTGCTCATC
GACGCGGTCGATCACCAGACCGCTTTTACGGTCTCTGAAACGGGGCTCACCCGCCCGAGCGCCGCCACGGGCGGCGAGCG
GTTCGCGCTGCCCCTGCGTCCGGGCGAGACACCTTTTACCTTCAGCGCCGATCGGCCGTTTATGTTCGCCGTGGTCAACA
CTTACTCCGGCTTCGTGGCGATGCTGGGCACCGTCATCGATCCGACCCAGCCCTGA

Upstream 100 bases:

>100_bases
TCTGTCGAACGCGATGCAGAAAGTCTGGTGGCTGGCGGTGGCGCTGGTCTGCTTGGGGGGTTCGGTAAGGGCCGCCGCGG
CGCCCATCGGGGCCGCACCG

Downstream 100 bases:

>100_bases
GCAAAGAATTGCTTAATTGTGGCTAGGCTCGGGACGCCTCCCCTGCACAATGGAATAAACGCGACAGGTGCCTATGTCCG
CTGAACGGCAAGCCTGGCTC

Product: serine protease inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MADRVEVPTFIQMREANWRFGFKLLSLINEAPLRANRERSPLAVERNVLLSPLGLGITLGRLLPSLSETAQRAVASSLEW
PNDGLIEPQSATALLAAQLTGADPQVQPVHAGLYWVEPGTPVKLGRDLSGNRVLESAFQDGAAPPEINRWIAAATGGQIG
EALIPGPRRPGPLVVVDATVFEGIWSRAFNPQSSLQAPFTLLDGKQTTVWQMSRTGSFRYYETPGFQAVQLPFGGDGEWS
MAVFVPAAGVPLRSFVRNLSDEKWRLWFEQFRMRDGSVTLPRLRLRYGQDLRRALRALGMRSAFTRSEGEESLGEAGLLI
DAVDHQTAFTVSETGLTRPSAATGGERFALPLRPGETPFTFSADRPFMFAVVNTYSGFVAMLGTVIDPTQP

Sequences:

>Translated_391_residues
MADRVEVPTFIQMREANWRFGFKLLSLINEAPLRANRERSPLAVERNVLLSPLGLGITLGRLLPSLSETAQRAVASSLEW
PNDGLIEPQSATALLAAQLTGADPQVQPVHAGLYWVEPGTPVKLGRDLSGNRVLESAFQDGAAPPEINRWIAAATGGQIG
EALIPGPRRPGPLVVVDATVFEGIWSRAFNPQSSLQAPFTLLDGKQTTVWQMSRTGSFRYYETPGFQAVQLPFGGDGEWS
MAVFVPAAGVPLRSFVRNLSDEKWRLWFEQFRMRDGSVTLPRLRLRYGQDLRRALRALGMRSAFTRSEGEESLGEAGLLI
DAVDHQTAFTVSETGLTRPSAATGGERFALPLRPGETPFTFSADRPFMFAVVNTYSGFVAMLGTVIDPTQP
>Mature_390_residues
ADRVEVPTFIQMREANWRFGFKLLSLINEAPLRANRERSPLAVERNVLLSPLGLGITLGRLLPSLSETAQRAVASSLEWP
NDGLIEPQSATALLAAQLTGADPQVQPVHAGLYWVEPGTPVKLGRDLSGNRVLESAFQDGAAPPEINRWIAAATGGQIGE
ALIPGPRRPGPLVVVDATVFEGIWSRAFNPQSSLQAPFTLLDGKQTTVWQMSRTGSFRYYETPGFQAVQLPFGGDGEWSM
AVFVPAAGVPLRSFVRNLSDEKWRLWFEQFRMRDGSVTLPRLRLRYGQDLRRALRALGMRSAFTRSEGEESLGEAGLLID
AVDHQTAFTVSETGLTRPSAATGGERFALPLRPGETPFTFSADRPFMFAVVNTYSGFVAMLGTVIDPTQP

Specific function: Unknown

COG id: COG4826

COG function: function code O; Serine protease inhibitor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serpin family [H]

Homologues:

Organism=Homo sapiens, GI156071456, Length=251, Percent_Identity=27.4900398406374, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI32454741, Length=256, Percent_Identity=26.953125, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4502261, Length=262, Percent_Identity=27.0992366412214, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI13489087, Length=390, Percent_Identity=27.1794871794872, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI4758906, Length=251, Percent_Identity=27.4900398406374, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI24307907, Length=359, Percent_Identity=23.6768802228412, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41152086, Length=250, Percent_Identity=27.2, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI211904152, Length=358, Percent_Identity=23.463687150838, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI5453886, Length=365, Percent_Identity=22.1917808219178, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI211904156, Length=358, Percent_Identity=23.463687150838, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI170295807, Length=364, Percent_Identity=22.8021978021978, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4826904, Length=364, Percent_Identity=22.8021978021978, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI260064048, Length=252, Percent_Identity=27.3809523809524, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI115583663, Length=252, Percent_Identity=27.3809523809524, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI260064050, Length=252, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI219689110, Length=260, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4505595, Length=260, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38504673, Length=251, Percent_Identity=27.8884462151394, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI38504669, Length=251, Percent_Identity=27.8884462151394, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4826902, Length=252, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI73858566, Length=253, Percent_Identity=23.3201581027668, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI5902072, Length=409, Percent_Identity=23.2273838630807, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI259155306, Length=253, Percent_Identity=28.8537549407115, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI10835159, Length=253, Percent_Identity=28.8537549407115, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI8393956, Length=251, Percent_Identity=26.2948207171315, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4505149, Length=232, Percent_Identity=26.7241379310345, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI92859634, Length=232, Percent_Identity=26.7241379310345, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI194018472, Length=265, Percent_Identity=23.7735849056604, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI28076869, Length=406, Percent_Identity=21.9211822660099, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI17998551, Length=254, Percent_Identity=25.1968503937008, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI110225349, Length=265, Percent_Identity=24.9056603773585, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI110225347, Length=398, Percent_Identity=23.1155778894472, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17563490, Length=289, Percent_Identity=24.5674740484429, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17563482, Length=230, Percent_Identity=24.3478260869565, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71990592, Length=292, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193207793, Length=288, Percent_Identity=24.3055555555556, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71990584, Length=288, Percent_Identity=24.3055555555556, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17975583, Length=239, Percent_Identity=26.3598326359833, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360250, Length=348, Percent_Identity=25.5747126436782, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357591, Length=267, Percent_Identity=24.7191011235955, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360253, Length=251, Percent_Identity=25.4980079681275, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24586111, Length=251, Percent_Identity=25.4980079681275, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17933714, Length=369, Percent_Identity=23.5772357723577, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582753, Length=342, Percent_Identity=25.1461988304094, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550372, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864502, Length=256, Percent_Identity=28.125, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI45552471, Length=244, Percent_Identity=28.6885245901639, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45552477, Length=244, Percent_Identity=28.6885245901639, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355737, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI78707176, Length=246, Percent_Identity=26.4227642276423, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586176, Length=246, Percent_Identity=26.4227642276423, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586105, Length=240, Percent_Identity=28.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586107, Length=240, Percent_Identity=28.3333333333333, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000215 [H]

Pfam domain/function: PF00079 Serpin [H]

EC number: NA

Molecular weight: Translated: 42767; Mature: 42636

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRVEVPTFIQMREANWRFGFKLLSLINEAPLRANRERSPLAVERNVLLSPLGLGITLG
CCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEECCCCHHHHHH
RLLPSLSETAQRAVASSLEWPNDGLIEPQSATALLAAQLTGADPQVQPVHAGLYWVEPGT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEECCCCCCCCEEEECCEEEECCCC
PVKLGRDLSGNRVLESAFQDGAAPPEINRWIAAATGGQIGEALIPGPRRPGPLVVVDATV
CEEECCCCCCCHHHHHHHHCCCCCCHHHHEEEECCCCCCCHHCCCCCCCCCCEEEEEHHH
FEGIWSRAFNPQSSLQAPFTLLDGKQTTVWQMSRTGSFRYYETPGFQAVQLPFGGDGEWS
HHHHHHHCCCCCHHCCCCEEEECCCCCEEEEEECCCCEEEEECCCCEEEEECCCCCCCEE
MAVFVPAAGVPLRSFVRNLSDEKWRLWFEQFRMRDGSVTLPRLRLRYGQDLRRALRALGM
EEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHCH
RSAFTRSEGEESLGEAGLLIDAVDHQTAFTVSETGLTRPSAATGGERFALPLRPGETPFT
HHHHHHCCCHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCEE
FSADRPFMFAVVNTYSGFVAMLGTVIDPTQP
ECCCCCEEEEEEHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADRVEVPTFIQMREANWRFGFKLLSLINEAPLRANRERSPLAVERNVLLSPLGLGITLG
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEECCCCHHHHHH
RLLPSLSETAQRAVASSLEWPNDGLIEPQSATALLAAQLTGADPQVQPVHAGLYWVEPGT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEECCCCCCCCEEEECCEEEECCCC
PVKLGRDLSGNRVLESAFQDGAAPPEINRWIAAATGGQIGEALIPGPRRPGPLVVVDATV
CEEECCCCCCCHHHHHHHHCCCCCCHHHHEEEECCCCCCCHHCCCCCCCCCCEEEEEHHH
FEGIWSRAFNPQSSLQAPFTLLDGKQTTVWQMSRTGSFRYYETPGFQAVQLPFGGDGEWS
HHHHHHHCCCCCHHCCCCEEEECCCCCEEEEEECCCCEEEEECCCCEEEEECCCCCCCEE
MAVFVPAAGVPLRSFVRNLSDEKWRLWFEQFRMRDGSVTLPRLRLRYGQDLRRALRALGM
EEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHCH
RSAFTRSEGEESLGEAGLLIDAVDHQTAFTVSETGLTRPSAATGGERFALPLRPGETPFT
HHHHHHCCCHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCEE
FSADRPFMFAVVNTYSGFVAMLGTVIDPTQP
ECCCCCEEEEEEHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA