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The map label for this gene is cysH

Identifier: 37521225

GI number: 37521225

Start: 1771133

End: 1771858

Strand: Direct

Name: cysH

Synonym: glr1656

Alternate gene names: 37521225

Gene position: 1771133-1771858 (Clockwise)

Preceding gene: 37521219

Following gene: 37521229

Centisome position: 38.02

GC content: 64.6

Gene sequence:

>726_bases
GTGAATTTACTGCAGGACCAACCGGCGATGGGCATCGACCAGACGACTCTGGAGCATCTGGCCCGGCAGTGGGAGGATCT
GGCTCCTGAGGCCATCCTGGCGGAAGCGGTGCGCTGTTTTGGCGACAAGTTGGTGCTGGCGAGCGCCTTCGGTCCCGAGT
CGATCATTTTGCTCGACATGCTGGTGAAGGTGTGGCCCCGGCCGCAGGCATTCTTCCTCGAGACGGGCTTTCATTTTCCC
GAGACGCTGGCGCTCAAAGACCGGGTGCTCGCGCGCTTTCCGCAGTTGCAGCTTGAGGTGGTGGGGCCGCTGATGTCCGT
CGCTCAGCAAAATGCCATCTACGGCGAGCGCCTGCACGATCGCAACCCGGATCATTGCTGCGCCATTCGCAAAGTCGAGC
CGCTCAACCGCGCCCTCGCCCCTTACAAAGCCTGGATTGCCGGCATGCGCCGCGAACAGTCGCCGACCCGCGGCCAGATT
GGCGTCGTGCAGTGGGATTCGCGCCGCGGCATGGTCAAGTTCAATCCGCTGGCCACCTGGACGCACAAGCAAGTCTGGGC
CTACATTGTCGAGCGCGATTTGCCCTATAACCCCCTGCACGACGAGGGGTTTCCGTCGATCGGCTGCTCGCCTCTTAACT
GCACCGCCCCGGTGGCCGACGGGGCGGACCCGCGCTCGGGGCGCTGGCGGGGCAAGGCCAAGACCGAGTGCGGCCTGCAT
GCGTGA

Upstream 100 bases:

>100_bases
CCACGTCAATTCCCGCAATGTCAAGCAGATAACGGGAGCAAATCTCTCTTTTTCCCCTGGGCTTACTGTACAATCAGAGC
AATCAGGTAGGGGCGCTTAC

Downstream 100 bases:

>100_bases
ATTTATTTACGGTCCGGAAGCTGGACGTCCCGAAGCCAGGTGGTGACCGCCTGGGCAAAGGCGCTCTCCAGCGCAATATA
GGGCGGCCAACCGGCGAGGG

Product: phosphoadenosine phosphosulfate

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNLLQDQPAMGIDQTTLEHLARQWEDLAPEAILAEAVRCFGDKLVLASAFGPESIILLDMLVKVWPRPQAFFLETGFHFP
ETLALKDRVLARFPQLQLEVVGPLMSVAQQNAIYGERLHDRNPDHCCAIRKVEPLNRALAPYKAWIAGMRREQSPTRGQI
GVVQWDSRRGMVKFNPLATWTHKQVWAYIVERDLPYNPLHDEGFPSIGCSPLNCTAPVADGADPRSGRWRGKAKTECGLH
A

Sequences:

>Translated_241_residues
MNLLQDQPAMGIDQTTLEHLARQWEDLAPEAILAEAVRCFGDKLVLASAFGPESIILLDMLVKVWPRPQAFFLETGFHFP
ETLALKDRVLARFPQLQLEVVGPLMSVAQQNAIYGERLHDRNPDHCCAIRKVEPLNRALAPYKAWIAGMRREQSPTRGQI
GVVQWDSRRGMVKFNPLATWTHKQVWAYIVERDLPYNPLHDEGFPSIGCSPLNCTAPVADGADPRSGRWRGKAKTECGLH
A
>Mature_241_residues
MNLLQDQPAMGIDQTTLEHLARQWEDLAPEAILAEAVRCFGDKLVLASAFGPESIILLDMLVKVWPRPQAFFLETGFHFP
ETLALKDRVLARFPQLQLEVVGPLMSVAQQNAIYGERLHDRNPDHCCAIRKVEPLNRALAPYKAWIAGMRREQSPTRGQI
GVVQWDSRRGMVKFNPLATWTHKQVWAYIVERDLPYNPLHDEGFPSIGCSPLNCTAPVADGADPRSGRWRGKAKTECGLH
A

Specific function: Reduction of activated sulfate into sulfite

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily

Homologues:

Organism=Escherichia coli, GI1789121, Length=220, Percent_Identity=33.1818181818182, Blast_Score=105, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6325425, Length=240, Percent_Identity=35.4166666666667, Blast_Score=144, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSH_GLOVI (Q7NK24)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924602.1
- HSSP:   P17854
- ProteinModelPortal:   Q7NK24
- SMR:   Q7NK24
- GeneID:   2598529
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr1656
- NMPDR:   fig|251221.1.peg.1656
- HOGENOM:   HBG758022
- OMA:   FEETLAY
- ProtClustDB:   CLSK423129
- BioCyc:   GVIO251221:GLR1656-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00063
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00434

Pfam domain/function: PF01507 PAPS_reduct

EC number: =1.8.4.8

Molecular weight: Translated: 27101; Mature: 27101

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLQDQPAMGIDQTTLEHLARQWEDLAPEAILAEAVRCFGDKLVLASAFGPESIILLDM
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
LVKVWPRPQAFFLETGFHFPETLALKDRVLARFPQLQLEVVGPLMSVAQQNAIYGERLHD
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
RNPDHCCAIRKVEPLNRALAPYKAWIAGMRREQSPTRGQIGVVQWDSRRGMVKFNPLATW
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCHH
THKQVWAYIVERDLPYNPLHDEGFPSIGCSPLNCTAPVADGADPRSGRWRGKAKTECGLH
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
A
C
>Mature Secondary Structure
MNLLQDQPAMGIDQTTLEHLARQWEDLAPEAILAEAVRCFGDKLVLASAFGPESIILLDM
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
LVKVWPRPQAFFLETGFHFPETLALKDRVLARFPQLQLEVVGPLMSVAQQNAIYGERLHD
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
RNPDHCCAIRKVEPLNRALAPYKAWIAGMRREQSPTRGQIGVVQWDSRRGMVKFNPLATW
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCHH
THKQVWAYIVERDLPYNPLHDEGFPSIGCSPLNCTAPVADGADPRSGRWRGKAKTECGLH
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292