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The map label for this gene is 37521229

Identifier: 37521229

GI number: 37521229

Start: 1773813

End: 1774841

Strand: Direct

Name: 37521229

Synonym: glr1660

Alternate gene names: NA

Gene position: 1773813-1774841 (Clockwise)

Preceding gene: 37521225

Following gene: 37521233

Centisome position: 38.07

GC content: 59.09

Gene sequence:

>1029_bases
ATGCGCAAAAAATACGATTACTGCATCTATATCGGCCGCTTTCAGCCGTTTCACCTGGGTCACCTGCAGACTGTGCGCAT
TGCCCTGGAGGAGGCGTCGGAGCTGATTATCGTCATCGGCAGCCACCGCACCGCCCCCAACATCAAAAATCCCTGGACCT
CCTCCCAGCGCGAGCAGATGATCCGCCTCACGCTCAAAGACGAACCGAACCTCCTGGAGCGCATCCACTTTGCGCCCGTG
CGCGACCAGCTCTACAGCGACAACCTCTGGGTGGCGGACATCCAACAAAAAGTGCTCGCCATCGCCGGGGACGAGAGCGC
CATCGCCATCATCGGTCACCGAAAAGACGAAAGCTCCTACTACCTGGATAGCTTTCCACAGTGGAGCTATATCGAGACGG
GCAATTACCGCGACATCCACTCCACCGATATCCGCGCCGCCTACTTGAGCCGCGCCCCCGAAGCCACGTACTACGACAAA
TTGCCGGTGGGGGTGCAGGTGAGCCTGAGCGCCTTTCAAAGCGAAGCGCGCTTCGGCGAACTCTGTGCCGAGTACGACTT
CATTCAACACAACCAAAAAGCCTGGTCGGTGGCTCCTTACCCACCCACCTTCGTGACCGTCGATGCGGTGGTGGTGCAGT
CGGGCCATGTGCTGATCGTCCGGCGCAAATCCCGCTACGGTTCGGGTCTCTACGCGCTACCCGGCGGCTTTGTCGATCAA
GACGAAACGCTGCTCGAAGGCATGTTGCGCGAACTCAAAGAAGAGACCGGTCTCAAGGTGCCGATGCCGGTGCTGCGCGG
TTCGATCGTCGACAGCCACGTCTTCGACAACCCGAGCCGCTCGCTGCGCGGCCGGACGATTACCCATGCCTACTTCATCC
AGCTCAAAGCGGGCAAGTTGCCGCCGGTTAAAGGCGGCGACGACGCCGACAAAGCCCTCTGGATGTCGCTTGCGGATCTG
TACATCCATGAAGATCTCTTTTTTGAAGATCACTTTGCCATCGTGCTGCACTTCGTAAGCCGGGTCTGA

Upstream 100 bases:

>100_bases
TAGCCTACCAGCTTGACCGGGGCTTGCAATTGCCGGGCTTTCTGTAGGATGGTATTGCCACCCCCGGAGAGGGGATGTTT
TTCATCACAGGGAGCCTGCG

Downstream 100 bases:

>100_bases
GTCCGATAGCCTGGCTGATCAACCGATACGGAGGGGCAAGCGCACCTGAAAGCGGGTGTCTCCCGGTTCGCAGAGTAAGC
GGACATCGCCATGGTGCTGC

Product: bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: Nicotinamide-nucleotide adenylyltransferase; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NMN adenylyltransferase; ADP compounds hydrolase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRKKYDYCIYIGRFQPFHLGHLQTVRIALEEASELIIVIGSHRTAPNIKNPWTSSQREQMIRLTLKDEPNLLERIHFAPV
RDQLYSDNLWVADIQQKVLAIAGDESAIAIIGHRKDESSYYLDSFPQWSYIETGNYRDIHSTDIRAAYLSRAPEATYYDK
LPVGVQVSLSAFQSEARFGELCAEYDFIQHNQKAWSVAPYPPTFVTVDAVVVQSGHVLIVRRKSRYGSGLYALPGGFVDQ
DETLLEGMLRELKEETGLKVPMPVLRGSIVDSHVFDNPSRSLRGRTITHAYFIQLKAGKLPPVKGGDDADKALWMSLADL
YIHEDLFFEDHFAIVLHFVSRV

Sequences:

>Translated_342_residues
MRKKYDYCIYIGRFQPFHLGHLQTVRIALEEASELIIVIGSHRTAPNIKNPWTSSQREQMIRLTLKDEPNLLERIHFAPV
RDQLYSDNLWVADIQQKVLAIAGDESAIAIIGHRKDESSYYLDSFPQWSYIETGNYRDIHSTDIRAAYLSRAPEATYYDK
LPVGVQVSLSAFQSEARFGELCAEYDFIQHNQKAWSVAPYPPTFVTVDAVVVQSGHVLIVRRKSRYGSGLYALPGGFVDQ
DETLLEGMLRELKEETGLKVPMPVLRGSIVDSHVFDNPSRSLRGRTITHAYFIQLKAGKLPPVKGGDDADKALWMSLADL
YIHEDLFFEDHFAIVLHFVSRV
>Mature_342_residues
MRKKYDYCIYIGRFQPFHLGHLQTVRIALEEASELIIVIGSHRTAPNIKNPWTSSQREQMIRLTLKDEPNLLERIHFAPV
RDQLYSDNLWVADIQQKVLAIAGDESAIAIIGHRKDESSYYLDSFPQWSYIETGNYRDIHSTDIRAAYLSRAPEATYYDK
LPVGVQVSLSAFQSEARFGELCAEYDFIQHNQKAWSVAPYPPTFVTVDAVVVQSGHVLIVRRKSRYGSGLYALPGGFVDQ
DETLLEGMLRELKEETGLKVPMPVLRGSIVDSHVFDNPSRSLRGRTITHAYFIQLKAGKLPPVKGGDDADKALWMSLADL
YIHEDLFFEDHFAIVLHFVSRV

Specific function: The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH [H]

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00293 NUDIX [H]

EC number: =2.7.7.1 [H]

Molecular weight: Translated: 38945; Mature: 38945

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKYDYCIYIGRFQPFHLGHLQTVRIALEEASELIIVIGSHRTAPNIKNPWTSSQREQM
CCCCEEEEEEECCCCCEECCCHHHHHHEECCCCEEEEEEECCCCCCCCCCCCCCCHHCEE
IRLTLKDEPNLLERIHFAPVRDQLYSDNLWVADIQQKVLAIAGDESAIAIIGHRKDESSY
EEEEECCCCCHHHHHCCCCHHHHHHCCCEEEEHHHHEEEEEECCCCEEEEEEECCCCCCE
YLDSFPQWSYIETGNYRDIHSTDIRAAYLSRAPEATYYDKLPVGVQVSLSAFQSEARFGE
ECCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
LCAEYDFIQHNQKAWSVAPYPPTFVTVDAVVVQSGHVLIVRRKSRYGSGLYALPGGFVDQ
HHHHHHHHHCCCCCEEECCCCCCEEEEEEEEEECCCEEEEEECCCCCCCEEECCCCCCCC
DETLLEGMLRELKEETGLKVPMPVLRGSIVDSHVFDNPSRSLRGRTITHAYFIQLKAGKL
HHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCCCCHHCCCCEEEEEEEEEEECCCC
PPVKGGDDADKALWMSLADLYIHEDLFFEDHFAIVLHFVSRV
CCCCCCCCHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHCC
>Mature Secondary Structure
MRKKYDYCIYIGRFQPFHLGHLQTVRIALEEASELIIVIGSHRTAPNIKNPWTSSQREQM
CCCCEEEEEEECCCCCEECCCHHHHHHEECCCCEEEEEEECCCCCCCCCCCCCCCHHCEE
IRLTLKDEPNLLERIHFAPVRDQLYSDNLWVADIQQKVLAIAGDESAIAIIGHRKDESSY
EEEEECCCCCHHHHHCCCCHHHHHHCCCEEEEHHHHEEEEEECCCCEEEEEEECCCCCCE
YLDSFPQWSYIETGNYRDIHSTDIRAAYLSRAPEATYYDKLPVGVQVSLSAFQSEARFGE
ECCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
LCAEYDFIQHNQKAWSVAPYPPTFVTVDAVVVQSGHVLIVRRKSRYGSGLYALPGGFVDQ
HHHHHHHHHCCCCCEEECCCCCCEEEEEEEEEECCCEEEEEECCCCCCCEEECCCCCCCC
DETLLEGMLRELKEETGLKVPMPVLRGSIVDSHVFDNPSRSLRGRTITHAYFIQLKAGKL
HHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCCCCHHCCCCEEEEEEEEEEECCCC
PPVKGGDDADKALWMSLADLYIHEDLFFEDHFAIVLHFVSRV
CCCCCCCCHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10050763 [H]