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The map label for this gene is yccK [H]

Identifier: 37520407

GI number: 37520407

Start: 892769

End: 893749

Strand: Reverse

Name: yccK [H]

Synonym: gll0838

Alternate gene names: 37520407

Gene position: 893749-892769 (Counterclockwise)

Preceding gene: 37520408

Following gene: 37520401

Centisome position: 19.18

GC content: 61.26

Gene sequence:

>981_bases
ATGAAAGTGCGCGCACTGGGCAATCAGGGACTGGTGGTCTCCGAACTTGGCCTCGGTTGCATGGGCATGTCTGAGTTCTA
CGGCGCCACCGACGAAACCGAGTCGATCGCCACCATCCACCGGGCGCTGGAACTGGGGATCAATTTTCTCGATACCGCCG
ACATGTATGGTCCCTACACTAACGAGCAGCTGGTGGGTAAAGCAATTCGCGACCGCCGCGACAAAGTGGTGCTCGCCACT
AAATTCGGCATCGTGCGCAGCGAAGACCGGGGCTTTCGCGGGGTGAACGGTTCACCGGAGTACGTGCGCTCCAGCTGCGA
AGCGTCCCTTGAACGGCTCGGGGTCGAAGTCATCGACCTGTACTACCTGCACCGGGTCGACCCGAAAGTCCCCATCGAGG
AGACCGTGGGGGCGATGGCCGAACTGGTGCAAGCGGGCAAGGTGCGCTTTATCGGTCTCTCGGAGGCGGCTCCCCAGACG
CTTCGCCGCGCCCAGAGAGTGCATCCGATTAGTGCCCTCCAGTCGGAATATTCGCTGTGGAGCCGCGACGTCGAGGATGA
GATTTTGCCCACCTTGCGGGAATTGGGCATCGGCTTTGTGCCCTACAGCCCGCTCGGACGGGGCTTTCTCTCCGGGAGCA
TCACCAGCCCCGACGACTTTGCTCCCGACGACTACCGTCGCCAGTCACCGCGCTTTCAGGGCGAGAACTTCACAAAGAAT
CTGCAACTGGTGGAGAAAGTCCGGGAACTGGCCACCCAAAAAGGCGTGCAGCCTTCGCAATTGGCCCTCGCCTGGATCCT
GGCGCAAGGCGAGGATCTCGTACCGATCCCCGGCACCAAGCGCGTCGCTTACCTGGAAGAAAACGTCGCCGCCACCGAAA
TTGTCCTCGCTCCCGAGGAACTGGCGAGCATTGAAGCGATTGCTCCCAGGGGAGCCGCTTCCGGGCAGCGCTATGCCGAT
ATGAGTGGGGTCAATCGATAA

Upstream 100 bases:

>100_bases
CTAGTTGGCGCAGTGCCTTGACTTAGAGCGCGCTCCAAGTTCTAAGGTGATCCCATACCTACCGCACTCACCATCCAGCA
ATTTTGCAGGAGCAACAACC

Downstream 100 bases:

>100_bases
CTTCGAGATAGCCTGGCGAAGTACGCCCTGGAAGCCATGCCTGTATGAGGTGCTGATTACCGATACTTACCCTCCAGATA
ATCAATATACTCATCGCGCA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKVRALGNQGLVVSELGLGCMGMSEFYGATDETESIATIHRALELGINFLDTADMYGPYTNEQLVGKAIRDRRDKVVLAT
KFGIVRSEDRGFRGVNGSPEYVRSSCEASLERLGVEVIDLYYLHRVDPKVPIEETVGAMAELVQAGKVRFIGLSEAAPQT
LRRAQRVHPISALQSEYSLWSRDVEDEILPTLRELGIGFVPYSPLGRGFLSGSITSPDDFAPDDYRRQSPRFQGENFTKN
LQLVEKVRELATQKGVQPSQLALAWILAQGEDLVPIPGTKRVAYLEENVAATEIVLAPEELASIEAIAPRGAASGQRYAD
MSGVNR

Sequences:

>Translated_326_residues
MKVRALGNQGLVVSELGLGCMGMSEFYGATDETESIATIHRALELGINFLDTADMYGPYTNEQLVGKAIRDRRDKVVLAT
KFGIVRSEDRGFRGVNGSPEYVRSSCEASLERLGVEVIDLYYLHRVDPKVPIEETVGAMAELVQAGKVRFIGLSEAAPQT
LRRAQRVHPISALQSEYSLWSRDVEDEILPTLRELGIGFVPYSPLGRGFLSGSITSPDDFAPDDYRRQSPRFQGENFTKN
LQLVEKVRELATQKGVQPSQLALAWILAQGEDLVPIPGTKRVAYLEENVAATEIVLAPEELASIEAIAPRGAASGQRYAD
MSGVNR
>Mature_326_residues
MKVRALGNQGLVVSELGLGCMGMSEFYGATDETESIATIHRALELGINFLDTADMYGPYTNEQLVGKAIRDRRDKVVLAT
KFGIVRSEDRGFRGVNGSPEYVRSSCEASLERLGVEVIDLYYLHRVDPKVPIEETVGAMAELVQAGKVRFIGLSEAAPQT
LRRAQRVHPISALQSEYSLWSRDVEDEILPTLRELGIGFVPYSPLGRGFLSGSITSPDDFAPDDYRRQSPRFQGENFTKN
LQLVEKVRELATQKGVQPSQLALAWILAQGEDLVPIPGTKRVAYLEENVAATEIVLAPEELASIEAIAPRGAASGQRYAD
MSGVNR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=319, Percent_Identity=31.974921630094, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4504825, Length=316, Percent_Identity=31.9620253164557, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI27436971, Length=332, Percent_Identity=29.2168674698795, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436964, Length=313, Percent_Identity=29.7124600638978, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI27436962, Length=313, Percent_Identity=29.3929712460064, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=29.3929712460064, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223718702, Length=289, Percent_Identity=30.7958477508651, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI41327764, Length=280, Percent_Identity=32.1428571428571, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI41152114, Length=223, Percent_Identity=30.4932735426009, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=34.9544072948328, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=36.4217252396166, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789375, Length=326, Percent_Identity=32.5153374233129, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787674, Length=305, Percent_Identity=30.4918032786885, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788081, Length=313, Percent_Identity=28.4345047923323, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=28.7790697674419, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI48994888, Length=202, Percent_Identity=27.7227722772277, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=28.1065088757396, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=27.7258566978193, Blast_Score=115, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=26.2626262626263, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6325384, Length=334, Percent_Identity=26.9461077844311, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=308, Percent_Identity=25.6493506493506, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=260, Percent_Identity=26.9230769230769, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646155, Length=311, Percent_Identity=27.3311897106109, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640980, Length=298, Percent_Identity=25.1677852348993, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646159, Length=293, Percent_Identity=27.3037542662116, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45549126, Length=302, Percent_Identity=26.158940397351, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129731, Length=345, Percent_Identity=26.3768115942029, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24657054, Length=327, Percent_Identity=22.3241590214067, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35801; Mature: 35801

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRALGNQGLVVSELGLGCMGMSEFYGATDETESIATIHRALELGINFLDTADMYGPYT
CCEEECCCCCEEHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCC
NEQLVGKAIRDRRDKVVLATKFGIVRSEDRGFRGVNGSPEYVRSSCEASLERLGVEVIDL
CHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHH
YYLHRVDPKVPIEETVGAMAELVQAGKVRFIGLSEAAPQTLRRAQRVHPISALQSEYSLW
HHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHH
SRDVEDEILPTLRELGIGFVPYSPLGRGFLSGSITSPDDFAPDDYRRQSPRFQGENFTKN
HCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCCCCCCHHHH
LQLVEKVRELATQKGVQPSQLALAWILAQGEDLVPIPGTKRVAYLEENVAATEIVLAPEE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCCCCEEEEECCCCCCEEEEECHHH
LASIEAIAPRGAASGQRYADMSGVNR
HHHHHHHCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MKVRALGNQGLVVSELGLGCMGMSEFYGATDETESIATIHRALELGINFLDTADMYGPYT
CCEEECCCCCEEHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCC
NEQLVGKAIRDRRDKVVLATKFGIVRSEDRGFRGVNGSPEYVRSSCEASLERLGVEVIDL
CHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHH
YYLHRVDPKVPIEETVGAMAELVQAGKVRFIGLSEAAPQTLRRAQRVHPISALQSEYSLW
HHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHH
SRDVEDEILPTLRELGIGFVPYSPLGRGFLSGSITSPDDFAPDDYRRQSPRFQGENFTKN
HCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCCCCCCHHHH
LQLVEKVRELATQKGVQPSQLALAWILAQGEDLVPIPGTKRVAYLEENVAATEIVLAPEE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCCCCEEEEECCCCCCEEEEECHHH
LASIEAIAPRGAASGQRYADMSGVNR
HHHHHHHCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]