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The map label for this gene is hflX [H]

Identifier: 34498295

GI number: 34498295

Start: 3094834

End: 3096222

Strand: Reverse

Name: hflX [H]

Synonym: CV_2840

Alternate gene names: 34498295

Gene position: 3096222-3094834 (Counterclockwise)

Preceding gene: 34498297

Following gene: 34498293

Centisome position: 65.17

GC content: 67.67

Gene sequence:

>1389_bases
ATGCAAACAGAAGTCAAAGAGACGCCCCGCTACGCCATCGTGGCCTCGGTGCAGTTGCCGGAAGTCAGCGACGCCGAGTT
CGAGGCCTCGCTCACCGAGCTGAGCGAGCTGGCCAAGACCCTGGGCTTCCAGGTGGTGCAGACTTTTGTGCAAAAGCGCA
GCAGCTTCGACCGCACCGCCTATATGGGCGTGGGCAAGCTCGACGAGATCAGCATGTACGTCAAGCGCGGCATCCGCGCC
GACGAGCTGGAGGACGAGCCGCAAGAGCTGGACGCCAGCTCGGTGGCGATCGACGCGCTGCTGGTGGACCATGAGATCTC
GCCGTCGCAGGCGCGCAATCTCGAGCTGGCGGTCGGCTGCGAGGTGATGGACCGCACCATGGTCATCCTGGAGATCTTCC
ATCGCAACGCCCGCTCGCGCGCGGCGCGCGCCCAGGTGGAAATCGCCCGTCTCGGCTACATGGCGCCGCGCCTGCGCGAG
GCGGCCAAGCTGGCCGGCCCGCAAGGCCGGCAGCGCAGCGGCATGGGCGGCCGAGGGGCCGGCGAATCGCATACCGAGCT
GGACCGCCGCAAGGTGCGCGACCGCATCGCCGAGCTGCAGCGCGAGATCGTCGCCATGGAGTTGGAGCGCAAGACGCAGC
GCGCGCGCCGCCTGGAGCGGCAGGGCCTGGGCCTGGGCGGCGTATCGCTGGTGGGCTACACCAACGCCGGCAAATCCACG
CTGATGCGGGCGCTGACCGGCAGCGAGGTGCTGGTGGCCAACAAGCTGTTCGCCACGCTGGACACCACGGTGCGGGTGCT
CCACCCGGAGAGCGTGCCGAGGGTGCTGGTCAGCGATACCGTGGGCTTCATCAAGAACCTGCCCCACGGCCTGGTGGCCT
CGTTCAAGTCCACGCTGGAAGAAGCGCTGGACGCCTCGCTGCTGCTGCATGCGATCGATGCCAGCGATCCCGGCTTCCAG
CGCCAGCTGGAGGTGACCGACGAGGTGTTGAGGGAAATCGGCGCCGACGACGTGCCGCGCATCCGCGTATTCAACAAGAT
TGACCATGTCGGCGACGAGGCCGAGCAGGCCGCCTGGACGGCGGAGCTGCGGCAGCGCTATCCCGGCTGCGTGGTGATGA
GCGCGCTGCGGCCGGAAGATGTCGCGAGTCTGCGCGCCGCCATTGTTGCTTTCTTCCAGCAAGACCTGGTAGAGGACGAA
TTGCTGCTGCCGTGGTCGGCGCAGCAGCTGCGCGGCGAAATCTACAGCCACTGCCAGGTGCTGGAGGAGCGCGCCGAGGA
GGAAGGCTGCTGGTTCCGCGTGCGCGGCGAGCCGGAAAAGCTGCGCAGCCTGCGCGAGCAGCTTAATCCGGGCTCCCAGG
GGCGGGAAAAGGAATACTGGGAGGCCTGA

Upstream 100 bases:

>100_bases
GCGGCGGCCGTCCGGTCAAGAAAGAACAGCGACTTGCCAGCGGGAAACGCCGTTTGCGGTTACTATCTGCTCTCTTCATC
CAAAGTAAAGCCATTCGCAG

Downstream 100 bases:

>100_bases
GCGGCCGCCGCAGCGAAAAGAGCCTTGTCGAGCAAGGCTCTTTTGCATTCTCCATCCCGAATGGCGTGCCGCTGGCGCAG
CAATCAGACTCCGGCCGGAC

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MQTEVKETPRYAIVASVQLPEVSDAEFEASLTELSELAKTLGFQVVQTFVQKRSSFDRTAYMGVGKLDEISMYVKRGIRA
DELEDEPQELDASSVAIDALLVDHEISPSQARNLELAVGCEVMDRTMVILEIFHRNARSRAARAQVEIARLGYMAPRLRE
AAKLAGPQGRQRSGMGGRGAGESHTELDRRKVRDRIAELQREIVAMELERKTQRARRLERQGLGLGGVSLVGYTNAGKST
LMRALTGSEVLVANKLFATLDTTVRVLHPESVPRVLVSDTVGFIKNLPHGLVASFKSTLEEALDASLLLHAIDASDPGFQ
RQLEVTDEVLREIGADDVPRIRVFNKIDHVGDEAEQAAWTAELRQRYPGCVVMSALRPEDVASLRAAIVAFFQQDLVEDE
LLLPWSAQQLRGEIYSHCQVLEERAEEEGCWFRVRGEPEKLRSLREQLNPGSQGREKEYWEA

Sequences:

>Translated_462_residues
MQTEVKETPRYAIVASVQLPEVSDAEFEASLTELSELAKTLGFQVVQTFVQKRSSFDRTAYMGVGKLDEISMYVKRGIRA
DELEDEPQELDASSVAIDALLVDHEISPSQARNLELAVGCEVMDRTMVILEIFHRNARSRAARAQVEIARLGYMAPRLRE
AAKLAGPQGRQRSGMGGRGAGESHTELDRRKVRDRIAELQREIVAMELERKTQRARRLERQGLGLGGVSLVGYTNAGKST
LMRALTGSEVLVANKLFATLDTTVRVLHPESVPRVLVSDTVGFIKNLPHGLVASFKSTLEEALDASLLLHAIDASDPGFQ
RQLEVTDEVLREIGADDVPRIRVFNKIDHVGDEAEQAAWTAELRQRYPGCVVMSALRPEDVASLRAAIVAFFQQDLVEDE
LLLPWSAQQLRGEIYSHCQVLEERAEEEGCWFRVRGEPEKLRSLREQLNPGSQGREKEYWEA
>Mature_462_residues
MQTEVKETPRYAIVASVQLPEVSDAEFEASLTELSELAKTLGFQVVQTFVQKRSSFDRTAYMGVGKLDEISMYVKRGIRA
DELEDEPQELDASSVAIDALLVDHEISPSQARNLELAVGCEVMDRTMVILEIFHRNARSRAARAQVEIARLGYMAPRLRE
AAKLAGPQGRQRSGMGGRGAGESHTELDRRKVRDRIAELQREIVAMELERKTQRARRLERQGLGLGGVSLVGYTNAGKST
LMRALTGSEVLVANKLFATLDTTVRVLHPESVPRVLVSDTVGFIKNLPHGLVASFKSTLEEALDASLLLHAIDASDPGFQ
RQLEVTDEVLREIGADDVPRIRVFNKIDHVGDEAEQAAWTAELRQRYPGCVVMSALRPEDVASLRAAIVAFFQQDLVEDE
LLLPWSAQQLRGEIYSHCQVLEERAEEEGCWFRVRGEPEKLRSLREQLNPGSQGREKEYWEA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=222, Percent_Identity=33.7837837837838, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI310124267, Length=222, Percent_Identity=33.7837837837838, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI310124171, Length=222, Percent_Identity=33.7837837837838, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI310124169, Length=222, Percent_Identity=33.7837837837838, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI310133116, Length=230, Percent_Identity=33.4782608695652, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI310133118, Length=264, Percent_Identity=32.9545454545455, Blast_Score=100, Evalue=5e-21,
Organism=Escherichia coli, GI1790615, Length=419, Percent_Identity=35.799522673031, Blast_Score=221, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI17561038, Length=260, Percent_Identity=31.1538461538462, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24650079, Length=353, Percent_Identity=32.0113314447592, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51616; Mature: 51616

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTEVKETPRYAIVASVQLPEVSDAEFEASLTELSELAKTLGFQVVQTFVQKRSSFDRTA
CCCCCHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YMGVGKLDEISMYVKRGIRADELEDEPQELDASSVAIDALLVDHEISPSQARNLELAVGC
HCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCHHHCCCEEEECH
EVMDRTMVILEIFHRNARSRAARAQVEIARLGYMAPRLREAAKLAGPQGRQRSGMGGRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GESHTELDRRKVRDRIAELQREIVAMELERKTQRARRLERQGLGLGGVSLVGYTNAGKST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHH
LMRALTGSEVLVANKLFATLDTTVRVLHPESVPRVLVSDTVGFIKNLPHGLVASFKSTLE
HHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
EALDASLLLHAIDASDPGFQRQLEVTDEVLREIGADDVPRIRVFNKIDHVGDEAEQAAWT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHH
AELRQRYPGCVVMSALRPEDVASLRAAIVAFFQQDLVEDELLLPWSAQQLRGEIYSHCQV
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHH
LEERAEEEGCWFRVRGEPEKLRSLREQLNPGSQGREKEYWEA
HHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTEVKETPRYAIVASVQLPEVSDAEFEASLTELSELAKTLGFQVVQTFVQKRSSFDRTA
CCCCCHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YMGVGKLDEISMYVKRGIRADELEDEPQELDASSVAIDALLVDHEISPSQARNLELAVGC
HCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCHHHCCCEEEECH
EVMDRTMVILEIFHRNARSRAARAQVEIARLGYMAPRLREAAKLAGPQGRQRSGMGGRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GESHTELDRRKVRDRIAELQREIVAMELERKTQRARRLERQGLGLGGVSLVGYTNAGKST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHH
LMRALTGSEVLVANKLFATLDTTVRVLHPESVPRVLVSDTVGFIKNLPHGLVASFKSTLE
HHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
EALDASLLLHAIDASDPGFQRQLEVTDEVLREIGADDVPRIRVFNKIDHVGDEAEQAAWT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHH
AELRQRYPGCVVMSALRPEDVASLRAAIVAFFQQDLVEDELLLPWSAQQLRGEIYSHCQV
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHH
LEERAEEEGCWFRVRGEPEKLRSLREQLNPGSQGREKEYWEA
HHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]