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The map label for this gene is soxR

Identifier: 34498248

GI number: 34498248

Start: 3027138

End: 3027584

Strand: Reverse

Name: soxR

Synonym: CV_2793

Alternate gene names: 34498248

Gene position: 3027584-3027138 (Counterclockwise)

Preceding gene: 34498253

Following gene: 34498246

Centisome position: 63.72

GC content: 68.68

Gene sequence:

>447_bases
ATGGAAGAAAGCACCATCACCATAGGCCGACTGGCCAAGCGGACCGGGGTGGCGGCCAGCGCCTTGCGCTTTTACGAGGC
GCGGGGCCTGATCCACAGTGTGGGCGAGGCGGGCAAGACCCGGCGCTACCGGCGCGACGCGATCCGCCGGGTGTCCTTCA
TCCGCGTCGCCCAGGCGATGGGCATGAGCCTGCAGGACATCGGCGCGGCGCTGGCCGACCTGCCTTCGCAGCGCACGCCG
ACGGCCGACGACTGGGCGCGGATCTCGCAGGCCTGGAAGCCGCTGCTGCAGGAACGGATAGACGCGCTGTGCCGGCTGCG
CGACCAGCTGGACAGCTGCATAGGCTGCGGCTGCTTGTCGCTGGAGCGCTGCAAGCTGTACAACCCGGACGACAAGGCGG
GCGAGCAGGGCTGCGGACCGCGTTTTCTGCTGGATGAAAAAGCCTGA

Upstream 100 bases:

>100_bases
CTGGAATAATAGACGATCTGGATATGGCTCATGTCGTTCGCGTGATCAATGGCGGTGATGCTAGTATCAAAGTTCAAGTT
AACTTGAAGTCAATGCGGAA

Downstream 100 bases:

>100_bases
GCCGCGTGGCGGCGTCCGCTTGGGTTTACAGCGCCTTGCGCAGGAAAATCCGACTGGCGCCCGGCGGATCGCAGGGGATC
TCCCCGAAAACCTGCCAGCC

Product: transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MEESTITIGRLAKRTGVAASALRFYEARGLIHSVGEAGKTRRYRRDAIRRVSFIRVAQAMGMSLQDIGAALADLPSQRTP
TADDWARISQAWKPLLQERIDALCRLRDQLDSCIGCGCLSLERCKLYNPDDKAGEQGCGPRFLLDEKA

Sequences:

>Translated_148_residues
MEESTITIGRLAKRTGVAASALRFYEARGLIHSVGEAGKTRRYRRDAIRRVSFIRVAQAMGMSLQDIGAALADLPSQRTP
TADDWARISQAWKPLLQERIDALCRLRDQLDSCIGCGCLSLERCKLYNPDDKAGEQGCGPRFLLDEKA
>Mature_148_residues
MEESTITIGRLAKRTGVAASALRFYEARGLIHSVGEAGKTRRYRRDAIRRVSFIRVAQAMGMSLQDIGAALADLPSQRTP
TADDWARISQAWKPLLQERIDALCRLRDQLDSCIGCGCLSLERCKLYNPDDKAGEQGCGPRFLLDEKA

Specific function: Activates The Transcription Of The Soxs Gene Which Itself Controls The Superoxide Response Regulon. Soxr Contains A 2fe-2s Iron-Sulfur Cluster That May Act As A Redox Sensor System That Recognizes Superoxide. The Variable Redox State Of The Fe-S Cluster I

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790498, Length=145, Percent_Identity=48.9655172413793, Blast_Score=149, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SOXR_CHRVO (Q9ZHI4)

Other databases:

- EMBL:   AF061445
- EMBL:   AE016825
- RefSeq:   NP_902463.1
- ProteinModelPortal:   Q9ZHI4
- SMR:   Q9ZHI4
- GeneID:   2548642
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2793
- NMPDR:   fig|243365.1.peg.2793
- HOGENOM:   HBG710951
- OMA:   SFILIAQ
- PhylomeDB:   Q9ZHI4
- ProtClustDB:   CLSK2503030
- BioCyc:   CVIO243365:CV_2793-MONOMER
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR010211
- InterPro:   IPR015358
- PRINTS:   PR00040
- SMART:   SM00422
- TIGRFAMs:   TIGR01950

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; SSF46955 Putativ_DNA_bind

EC number: NA

Molecular weight: Translated: 16427; Mature: 16427

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00552 HTH_MERR_1; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEESTITIGRLAKRTGVAASALRFYEARGLIHSVGEAGKTRRYRRDAIRRVSFIRVAQAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMSLQDIGAALADLPSQRTPTADDWARISQAWKPLLQERIDALCRLRDQLDSCIGCGCLS
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LERCKLYNPDDKAGEQGCGPRFLLDEKA
HHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEESTITIGRLAKRTGVAASALRFYEARGLIHSVGEAGKTRRYRRDAIRRVSFIRVAQAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMSLQDIGAALADLPSQRTPTADDWARISQAWKPLLQERIDALCRLRDQLDSCIGCGCLS
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LERCKLYNPDDKAGEQGCGPRFLLDEKA
HHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782