Click here to switch to the map view.

The map label for this gene is invG [H]

Identifier: 34498087

GI number: 34498087

Start: 2839446

End: 2841131

Strand: Reverse

Name: invG [H]

Synonym: CV_2632

Alternate gene names: 34498087

Gene position: 2841131-2839446 (Counterclockwise)

Preceding gene: 34498088

Following gene: 34498086

Centisome position: 59.8

GC content: 65.95

Gene sequence:

>1686_bases
ATGAACAAGCACCTTCTTTGCGCGCTGCTGTCCGGATGCGCGGTCCTGTTGGCCCAGCCCGCGGCGTCCGCGCCGCAGGC
GGCCGAATCCAGCGGCTACGTCGCCAAGAAAGATGGCCTGCGCGGCTTTTTCGACGCGCTATCGTCGCGGCTGAAGAAGC
CTGTGATCGTCAGCAAGCTGGCCGCGCGCAAGCAGATCAGCGGCGAGTTCGATCTTGCCAATCCGCAGGCGATGCTGGAA
AAGATGGCGCAGCAGCTGGGCCTGATCTGGTACCACGACGGCCAGGCCATCTATGTCTACGACGCCAGCGAGACGCGCAG
CTCCATCGTGTCGCTGCGCAACGTGTCGCTGCAGGCTTTCAACGATTTCCTGCGCAAGTCCGGCCTGTACGACAAGCGCT
ATCCGCTGCGCGGCGACGGCCGCAGCGGCACCTTCTACGTGTCCGGTCCGCCGGTGTTCGTCGACCTGGTGGTCAACGCC
GCCTCGATGATGGACAAGCAGAGCGACGGCCTGGAGCTTGGCCGGCAGAAGATTGGCGTGGTCAGGCTGGGTAATACCTT
TGTCGGCGACCGCACCTACGACCTGCGCGACCAGAAGATCGTCATTCCCGGCATGGCCACGGTGATCGAAAAGCTGCTGG
ACGGCGAGCGCAAGCCGGTCGCCGGCCTGGCTCCGCCCGCCGCCGAGAAGCGCGACGACATCCCGGCGATGCCGGACTTC
AAGGAGGGCAGGGGGCTGCCCTACCAGGCCGGCCTGAGCCTGCCCGAAGCGCTGAAGCGCGACGCCGCCGCCGGCGATAT
CAAGGTGATCGCCTATCCGGACACCAACAGCCTGCTGGTGAAGGGCACCGCCGAACAGGTGCGTTTCATCGAGAATCTGG
CGCGGGCGCTGGACGTGGCCAAGCGCCACGTCGAGCTGTCGCTGTGGATCATAGACCTGCAGAAGGACGACCTGGACCAA
CTGGGCGTCAACTGGAGCGGCAGCGTCACCGTGGGCAACAAGCTCGGCGTGACCTTGAACCAGGCGGGGTCGCTGAGCAC
GCTGGACGGCACCCGCTTCCTGGCCGCGGTGATGGCGATGACCAGCAAGAAAAAGGCCAACGTGGTGTCGCGTCCGGTGG
TGCTGACCCAGGAGAACATCCCGGCCATCTTCGACAACAACCGCACCTTCTACGCCAAGCTGGAAGGCGAGCGCAGCGTG
GACTTGCAGCATGTCACCTACGGCACGCTGATCAGCGTGCTGCCGCGCTTCGCCGCCGATGGCCAGATCGAAATGTCGCT
GAGCATAGAGGACGGCAGCCAGGCCCGCGCGCCCGACTATTCCAGCGACAACAAGGACGCCGGCCTGCCCGAGGTCGGCC
GCACCCGCATCAGCACCGTGGCCCGCGTGCCGCAGGGCAAGAGCCTGTTGATCGGCGGCTTCACCCGAGACGCCAGCGAG
CGCGGAGAGGGCAAGGTGCCGCTGTTGGGCGATCTGCCGCTGGTTGGGGGGCTGTTCCGCTATCAAAGCGCGAAACAGAC
CAATACCGTGCGGGTGTTCCTGATCCAGCCGCGCGAGATCGACGACGCGCTGACGCCGGACGCCAGCGACCTGTCGGCCG
ACCTGGTGCGCCGCGCCGGCATCGAGACCGATCCCTTGCAGCAGTGGGTCCGCAATTACCTGGACCGCGAGCAGCAGGAC
AAGTAG

Upstream 100 bases:

>100_bases
AGCACGGCTATGCGTCCTCCTCTCATTTTTCAAATGAAATCAAGGATCTGATCGGCGTCTCTCCGCGCGGTCTGTCCAAT
ATCATCCAGTTGGCTTCCAA

Downstream 100 bases:

>100_bases
ATGGCCGTCGACTTCACCCCGCGCACCGTCTTCAGCATCGGCCTGCGTTCGCCCAAGCAGATGGCCAGGGCCGAGGCGCA
GAAGGATGCGTTGAAGCAGA

Product: invasion protein - outer membrane

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MNKHLLCALLSGCAVLLAQPAASAPQAAESSGYVAKKDGLRGFFDALSSRLKKPVIVSKLAARKQISGEFDLANPQAMLE
KMAQQLGLIWYHDGQAIYVYDASETRSSIVSLRNVSLQAFNDFLRKSGLYDKRYPLRGDGRSGTFYVSGPPVFVDLVVNA
ASMMDKQSDGLELGRQKIGVVRLGNTFVGDRTYDLRDQKIVIPGMATVIEKLLDGERKPVAGLAPPAAEKRDDIPAMPDF
KEGRGLPYQAGLSLPEALKRDAAAGDIKVIAYPDTNSLLVKGTAEQVRFIENLARALDVAKRHVELSLWIIDLQKDDLDQ
LGVNWSGSVTVGNKLGVTLNQAGSLSTLDGTRFLAAVMAMTSKKKANVVSRPVVLTQENIPAIFDNNRTFYAKLEGERSV
DLQHVTYGTLISVLPRFAADGQIEMSLSIEDGSQARAPDYSSDNKDAGLPEVGRTRISTVARVPQGKSLLIGGFTRDASE
RGEGKVPLLGDLPLVGGLFRYQSAKQTNTVRVFLIQPREIDDALTPDASDLSADLVRRAGIETDPLQQWVRNYLDREQQD
K

Sequences:

>Translated_561_residues
MNKHLLCALLSGCAVLLAQPAASAPQAAESSGYVAKKDGLRGFFDALSSRLKKPVIVSKLAARKQISGEFDLANPQAMLE
KMAQQLGLIWYHDGQAIYVYDASETRSSIVSLRNVSLQAFNDFLRKSGLYDKRYPLRGDGRSGTFYVSGPPVFVDLVVNA
ASMMDKQSDGLELGRQKIGVVRLGNTFVGDRTYDLRDQKIVIPGMATVIEKLLDGERKPVAGLAPPAAEKRDDIPAMPDF
KEGRGLPYQAGLSLPEALKRDAAAGDIKVIAYPDTNSLLVKGTAEQVRFIENLARALDVAKRHVELSLWIIDLQKDDLDQ
LGVNWSGSVTVGNKLGVTLNQAGSLSTLDGTRFLAAVMAMTSKKKANVVSRPVVLTQENIPAIFDNNRTFYAKLEGERSV
DLQHVTYGTLISVLPRFAADGQIEMSLSIEDGSQARAPDYSSDNKDAGLPEVGRTRISTVARVPQGKSLLIGGFTRDASE
RGEGKVPLLGDLPLVGGLFRYQSAKQTNTVRVFLIQPREIDDALTPDASDLSADLVRRAGIETDPLQQWVRNYLDREQQD
K
>Mature_561_residues
MNKHLLCALLSGCAVLLAQPAASAPQAAESSGYVAKKDGLRGFFDALSSRLKKPVIVSKLAARKQISGEFDLANPQAMLE
KMAQQLGLIWYHDGQAIYVYDASETRSSIVSLRNVSLQAFNDFLRKSGLYDKRYPLRGDGRSGTFYVSGPPVFVDLVVNA
ASMMDKQSDGLELGRQKIGVVRLGNTFVGDRTYDLRDQKIVIPGMATVIEKLLDGERKPVAGLAPPAAEKRDDIPAMPDF
KEGRGLPYQAGLSLPEALKRDAAAGDIKVIAYPDTNSLLVKGTAEQVRFIENLARALDVAKRHVELSLWIIDLQKDDLDQ
LGVNWSGSVTVGNKLGVTLNQAGSLSTLDGTRFLAAVMAMTSKKKANVVSRPVVLTQENIPAIFDNNRTFYAKLEGERSV
DLQHVTYGTLISVLPRFAADGQIEMSLSIEDGSQARAPDYSSDNKDAGLPEVGRTRISTVARVPQGKSLLIGGFTRDASE
RGEGKVPLLGDLPLVGGLFRYQSAKQTNTVRVFLIQPREIDDALTPDASDLSADLVRRAGIETDPLQQWVRNYLDREQQD
K

Specific function: Involved in the invasion of the cells of the intestinal epithelium. Could be necessary for the export of invasion related determinants [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=262, Percent_Identity=25.9541984732824, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 61131; Mature: 61131

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKHLLCALLSGCAVLLAQPAASAPQAAESSGYVAKKDGLRGFFDALSSRLKKPVIVSKL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHH
AARKQISGEFDLANPQAMLEKMAQQLGLIWYHDGQAIYVYDASETRSSIVSLRNVSLQAF
HHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHH
NDFLRKSGLYDKRYPLRGDGRSGTFYVSGPPVFVDLVVNAASMMDKQSDGLELGRQKIGV
HHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCHHHHHHHCCE
VRLGNTFVGDRTYDLRDQKIVIPGMATVIEKLLDGERKPVAGLAPPAAEKRDDIPAMPDF
EEECCEEECCCEECCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
KEGRGLPYQAGLSLPEALKRDAAAGDIKVIAYPDTNSLLVKGTAEQVRFIENLARALDVA
CCCCCCCHHHCCCCHHHHHHCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHH
KRHVELSLWIIDLQKDDLDQLGVNWSGSVTVGNKLGVTLNQAGSLSTLDGTRFLAAVMAM
HHCEEEEEEEEECCCCCHHHCCCCCCCCEEECCCCCEEEECCCCCCCCCHHHHHHHHHHH
TSKKKANVVSRPVVLTQENIPAIFDNNRTFYAKLEGERSVDLQHVTYGTLISVLPRFAAD
HCCHHCCHHHCCEEEECCCCCEEEECCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCC
GQIEMSLSIEDGSQARAPDYSSDNKDAGLPEVGRTRISTVARVPQGKSLLIGGFTRDASE
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHH
RGEGKVPLLGDLPLVGGLFRYQSAKQTNTVRVFLIQPREIDDALTPDASDLSADLVRRAG
CCCCCCCEEECCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
IETDPLQQWVRNYLDREQQDK
CCCHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure
MNKHLLCALLSGCAVLLAQPAASAPQAAESSGYVAKKDGLRGFFDALSSRLKKPVIVSKL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHH
AARKQISGEFDLANPQAMLEKMAQQLGLIWYHDGQAIYVYDASETRSSIVSLRNVSLQAF
HHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHH
NDFLRKSGLYDKRYPLRGDGRSGTFYVSGPPVFVDLVVNAASMMDKQSDGLELGRQKIGV
HHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCHHHHHHHCCE
VRLGNTFVGDRTYDLRDQKIVIPGMATVIEKLLDGERKPVAGLAPPAAEKRDDIPAMPDF
EEECCEEECCCEECCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
KEGRGLPYQAGLSLPEALKRDAAAGDIKVIAYPDTNSLLVKGTAEQVRFIENLARALDVA
CCCCCCCHHHCCCCHHHHHHCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHH
KRHVELSLWIIDLQKDDLDQLGVNWSGSVTVGNKLGVTLNQAGSLSTLDGTRFLAAVMAM
HHCEEEEEEEEECCCCCHHHCCCCCCCCEEECCCCCEEEECCCCCCCCCHHHHHHHHHHH
TSKKKANVVSRPVVLTQENIPAIFDNNRTFYAKLEGERSVDLQHVTYGTLISVLPRFAAD
HCCHHCCHHHCCEEEECCCCCEEEECCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCC
GQIEMSLSIEDGSQARAPDYSSDNKDAGLPEVGRTRISTVARVPQGKSLLIGGFTRDASE
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHH
RGEGKVPLLGDLPLVGGLFRYQSAKQTNTVRVFLIQPREIDDALTPDASDLSADLVRRAG
CCCCCCCEEECCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
IETDPLQQWVRNYLDREQQDK
CCCHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868245; 7997169; 11677609 [H]