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The map label for this gene is sipD [H]

Identifier: 34498072

GI number: 34498072

Start: 2824350

End: 2825549

Strand: Reverse

Name: sipD [H]

Synonym: CV_2617

Alternate gene names: 34498072

Gene position: 2825549-2824350 (Counterclockwise)

Preceding gene: 34498073

Following gene: 34498071

Centisome position: 59.47

GC content: 65.0

Gene sequence:

>1200_bases
ATGTACGGCATTCAAACTTCCGCTTCTCTGCCGCTGACGCGGCCGCAAGCTCTCGAAACCCAGGCCGCCGCGCCGCAATC
CGACGCGCCGGACGCATCCGCCGGACAGACGCGCGCCGCGCCGCAGGGATCGGCCGCGCCGGCGCTGGCCGCCGCCCGGG
CCAAGGCCGACGAGTTGGGCCAGGCCGCGCGCGAGGTCCGCGCCAGCGTCGAACGCCAGACCGCTTACGAAACCAGGCTG
GCGGCACAACGCTCGGCGGCGGCGTTCTCCGGCGGCGAACCGCCGCAGGCCAGGCGCGAGGCGCCGGGCGCGGAACTGGA
CGAGGCCCGGAACGCGCAGACCGTGAGCGCCAGGCTGTTCGAAGGCAATCTGAAAGGCGTGGCGCAAAGCGGCCACGCGA
TGAGCGCAGAGCAAAAGCAGGCGCTGCAGTCCGGGCTGGACGACGTGTTCGCCGACGCGCCGCCCCAGGCCCGCTCCGCC
GGCGCGCCCATGCTGTACTCGGCGAATGCCGCCGCCGGCCAGGGCATGGCGGACAGCGACCTGTGGGACATGATCAGCGA
CCAAATCGGCAAGATCAAGGACAACTACCTGGGCGTCTACGAGAACGTGGTCGGCCAGTACACCGATTTCTACAAGGCGT
TCAGCGACATCCTGTCGCAGATGGCCAACTGGATCAAACCCGGCGGCGACGGCAACAAGGTCAAGTTGAACGTGGACGCG
TTGAAGGCCGCGCTGGAAAAGCTGAAAAAGGATTTTTCGCTGGGCGACAACTTGGACAACAAGAAGGCCGTGCTGTTTCC
GGCGCAGAGCAAGGATGGCGGCATTCAGGGCGGCAGCGAGAGCGACGCCAGAAAGTGGGCCAAGGAAATGGGATTGCCCG
ATGCTCCTCCCCCAGGATTTTCTTGTGTTCAAAAAGCGGCCGACGGCAACTGGGTCGTGGTGGTCGACATGACGCCGATC
GACACCATGATCCGGGATGTGGGCGCGCTGGGCAGCGGCACCGAGCTGGAACTGGACAACGCTAAGTTCCAGGCTTGGCA
GTCCGGTTTCAAGGCGCAGGAGGAAAACCTGAAAAACACCCTGCAGACGCTGACCCAGAAGTACAGCAACGCCAACTCGC
TGTTCGACAACCTGGTCAAGGTGCTCAGCAGCACCATCAGCAGCTGCCTGGAAACCGCCAAGTCCTTCCTGCAAATCTGA

Upstream 100 bases:

>100_bases
GCCCCGGCTTTCGCGGCCGGGGCGGCTTTCCGCACCATTCATCCCGCCAGCGTCGCCGTGCGTGCCCAGGCGCCGGCGCT
GGCCCCGCAGGGGGATTTCC

Downstream 100 bases:

>100_bases
ACGCACAGGAGCGCCACACATGCCCATCACAGGAGCTTCCCACGCCGCGATGCGCCCCTTGTCCGCGCCGCCGGACGGAA
CGGCCGGCCCCGCCAGTCCG

Product: pathogenicity island 1 effector protein

Products: NA

Alternate protein names: Salmonella invasion protein D [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MYGIQTSASLPLTRPQALETQAAAPQSDAPDASAGQTRAAPQGSAAPALAAARAKADELGQAAREVRASVERQTAYETRL
AAQRSAAAFSGGEPPQARREAPGAELDEARNAQTVSARLFEGNLKGVAQSGHAMSAEQKQALQSGLDDVFADAPPQARSA
GAPMLYSANAAAGQGMADSDLWDMISDQIGKIKDNYLGVYENVVGQYTDFYKAFSDILSQMANWIKPGGDGNKVKLNVDA
LKAALEKLKKDFSLGDNLDNKKAVLFPAQSKDGGIQGGSESDARKWAKEMGLPDAPPPGFSCVQKAADGNWVVVVDMTPI
DTMIRDVGALGSGTELELDNAKFQAWQSGFKAQEENLKNTLQTLTQKYSNANSLFDNLVKVLSSTISSCLETAKSFLQI

Sequences:

>Translated_399_residues
MYGIQTSASLPLTRPQALETQAAAPQSDAPDASAGQTRAAPQGSAAPALAAARAKADELGQAAREVRASVERQTAYETRL
AAQRSAAAFSGGEPPQARREAPGAELDEARNAQTVSARLFEGNLKGVAQSGHAMSAEQKQALQSGLDDVFADAPPQARSA
GAPMLYSANAAAGQGMADSDLWDMISDQIGKIKDNYLGVYENVVGQYTDFYKAFSDILSQMANWIKPGGDGNKVKLNVDA
LKAALEKLKKDFSLGDNLDNKKAVLFPAQSKDGGIQGGSESDARKWAKEMGLPDAPPPGFSCVQKAADGNWVVVVDMTPI
DTMIRDVGALGSGTELELDNAKFQAWQSGFKAQEENLKNTLQTLTQKYSNANSLFDNLVKVLSSTISSCLETAKSFLQI
>Mature_399_residues
MYGIQTSASLPLTRPQALETQAAAPQSDAPDASAGQTRAAPQGSAAPALAAARAKADELGQAAREVRASVERQTAYETRL
AAQRSAAAFSGGEPPQARREAPGAELDEARNAQTVSARLFEGNLKGVAQSGHAMSAEQKQALQSGLDDVFADAPPQARSA
GAPMLYSANAAAGQGMADSDLWDMISDQIGKIKDNYLGVYENVVGQYTDFYKAFSDILSQMANWIKPGGDGNKVKLNVDA
LKAALEKLKKDFSLGDNLDNKKAVLFPAQSKDGGIQGGSESDARKWAKEMGLPDAPPPGFSCVQKAADGNWVVVVDMTPI
DTMIRDVGALGSGTELELDNAKFQAWQSGFKAQEENLKNTLQTLTQKYSNANSLFDNLVKVLSSTISSCLETAKSFLQI

Specific function: Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of sipA, sipB, and sipC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS). Localizes to the tip of the external secretion needle that is part of the TTSS apparatus (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the invasin protein D family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009483
- InterPro:   IPR013386 [H]

Pfam domain/function: PF06511 IpaD [H]

EC number: NA

Molecular weight: Translated: 42223; Mature: 42223

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGIQTSASLPLTRPQALETQAAAPQSDAPDASAGQTRAAPQGSAAPALAAARAKADELG
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QAAREVRASVERQTAYETRLAAQRSAAAFSGGEPPQARREAPGAELDEARNAQTVSARLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHCCCHHHHHHHH
EGNLKGVAQSGHAMSAEQKQALQSGLDDVFADAPPQARSAGAPMLYSANAAAGQGMADSD
HCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEECCCCCCCCCCCHH
LWDMISDQIGKIKDNYLGVYENVVGQYTDFYKAFSDILSQMANWIKPGGDGNKVKLNVDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHH
LKAALEKLKKDFSLGDNLDNKKAVLFPAQSKDGGIQGGSESDARKWAKEMGLPDAPPPGF
HHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCH
SCVQKAADGNWVVVVDMTPIDTMIRDVGALGSGTELELDNAKFQAWQSGFKAQEENLKNT
HHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
LQTLTQKYSNANSLFDNLVKVLSSTISSCLETAKSFLQI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYGIQTSASLPLTRPQALETQAAAPQSDAPDASAGQTRAAPQGSAAPALAAARAKADELG
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QAAREVRASVERQTAYETRLAAQRSAAAFSGGEPPQARREAPGAELDEARNAQTVSARLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHCCCHHHHHHHH
EGNLKGVAQSGHAMSAEQKQALQSGLDDVFADAPPQARSAGAPMLYSANAAAGQGMADSD
HCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEECCCCCCCCCCCHH
LWDMISDQIGKIKDNYLGVYENVVGQYTDFYKAFSDILSQMANWIKPGGDGNKVKLNVDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHH
LKAALEKLKKDFSLGDNLDNKKAVLFPAQSKDGGIQGGSESDARKWAKEMGLPDAPPPGF
HHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCH
SCVQKAADGNWVVVVDMTPIDTMIRDVGALGSGTELELDNAKFQAWQSGFKAQEENLKNT
HHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
LQTLTQKYSNANSLFDNLVKVLSSTISSCLETAKSFLQI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA