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The map label for this gene is sseB [H]

Identifier: 34498038

GI number: 34498038

Start: 2785725

End: 2786279

Strand: Reverse

Name: sseB [H]

Synonym: CV_2583

Alternate gene names: 34498038

Gene position: 2786279-2785725 (Counterclockwise)

Preceding gene: 34498046

Following gene: 34498037

Centisome position: 58.65

GC content: 54.59

Gene sequence:

>555_bases
ATGTCTAGTATTAATGCTCAAGGCGGTGTGCAACCTGCATCTATTACTACCGATGAGGTGATCGATAACGATCACATCGA
GTATCTGCGCGCGGCGCGGAACTACTCGCTGCTGGGCCAGGCCATCGCCACGATGGAAGAGGTCATGCTGCTGTTTACCG
AACTGTCCAATGCCAAGTTCGCGCAGATGTCGAAGAAAATGGAAGTGTCGCGCGATGCGCAGGAAATGGCCAATAAAGTG
GAGGCAGTGCTGGCAGGCATCACCGACCCCAAAGATACCAAGAAACTGCCTCAGGATGTGCTGGATTATCTGAAGGCTAA
CGGCATCAGCGTGGATTCGGTGGAAAACCTCGAGGGCGATCTCAGCCAGGCGGATCTGACGGCAGTGAAATCTGCGCTGG
AGTCCTTCTCCGGCCGCGCGTCTGACTTCGTGCAGCAAAGCCAGTTGAAGATGCAGCAGCTGATTCAGAACTTCAACACC
GCGGTGACCATGGCCAACAGTTTGCAGAGCATGAACGCGGAATCGACCAAGTCCATCGCCCAGGCTATCCGTTAA

Upstream 100 bases:

>100_bases
TATCATGCAGCAGTCGAAGTTGAGGCGCAGATTGTGTGGCGATAATGACTTTGATAGTGAAAAGCATCAATTTTAATCTT
GAATTTTTAAAGGTGACTAT

Downstream 100 bases:

>100_bases
TGGATAAAGGCAGGCGGGTCAGTGCGCGGCGCCTGCCTCCCAATACCACTCTTGAAAGGAAATATCGATGAACACTACCG
TAAACCAAACTACTCCCGGC

Product: secreted protein EspA

Products: NA

Alternate protein names: Secretion system effector B [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSSINAQGGVQPASITTDEVIDNDHIEYLRAARNYSLLGQAIATMEEVMLLFTELSNAKFAQMSKKMEVSRDAQEMANKV
EAVLAGITDPKDTKKLPQDVLDYLKANGISVDSVENLEGDLSQADLTAVKSALESFSGRASDFVQQSQLKMQQLIQNFNT
AVTMANSLQSMNAESTKSIAQAIR

Sequences:

>Translated_184_residues
MSSINAQGGVQPASITTDEVIDNDHIEYLRAARNYSLLGQAIATMEEVMLLFTELSNAKFAQMSKKMEVSRDAQEMANKV
EAVLAGITDPKDTKKLPQDVLDYLKANGISVDSVENLEGDLSQADLTAVKSALESFSGRASDFVQQSQLKMQQLIQNFNT
AVTMANSLQSMNAESTKSIAQAIR
>Mature_183_residues
SSINAQGGVQPASITTDEVIDNDHIEYLRAARNYSLLGQAIATMEEVMLLFTELSNAKFAQMSKKMEVSRDAQEMANKVE
AVLAGITDPKDTKKLPQDVLDYLKANGISVDSVENLEGDLSQADLTAVKSALESFSGRASDFVQQSQLKMQQLIQNFNTA
VTMANSLQSMNAESTKSIAQAIR

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells. SseB i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted via type III secretion system 2 (SPI-2 TTSS). After secretion, localizes mainly on the surface of the bacterial cell [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the espA/sseB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005095 [H]

Pfam domain/function: PF03433 EspA [H]

EC number: NA

Molecular weight: Translated: 20025; Mature: 19894

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSINAQGGVQPASITTDEVIDNDHIEYLRAARNYSLLGQAIATMEEVMLLFTELSNAKF
CCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AQMSKKMEVSRDAQEMANKVEAVLAGITDPKDTKKLPQDVLDYLKANGISVDSVENLEGD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
LSQADLTAVKSALESFSGRASDFVQQSQLKMQQLIQNFNTAVTMANSLQSMNAESTKSIA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QAIR
HHHC
>Mature Secondary Structure 
SSINAQGGVQPASITTDEVIDNDHIEYLRAARNYSLLGQAIATMEEVMLLFTELSNAKF
CCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AQMSKKMEVSRDAQEMANKVEAVLAGITDPKDTKKLPQDVLDYLKANGISVDSVENLEGD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
LSQADLTAVKSALESFSGRASDFVQQSQLKMQQLIQNFNTAVTMANSLQSMNAESTKSIA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QAIR
HHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9786193; 9786194; 11677609 [H]