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The map label for this gene is hupB1 [H]

Identifier: 34498009

GI number: 34498009

Start: 2747507

End: 2747776

Strand: Reverse

Name: hupB1 [H]

Synonym: CV_2554

Alternate gene names: 34498009

Gene position: 2747776-2747507 (Counterclockwise)

Preceding gene: 34498010

Following gene: 34498008

Centisome position: 57.83

GC content: 60.74

Gene sequence:

>270_bases
GTGAACAAGTCTGAACTGATTGACGCCATCGCGGCTGAAGCCGACATCTCCAAGGCTGCTGCTGCCAAGGCTCTGGACGG
CATGGTTGCTGCCGTTACCTCTGCCTTGAAAAAAGGCGATACCGTGACCCTGGTGGGTTTCGGCACCTTCTACGTGGGCG
AGCGCGCTGAGCGCAGCGGCCGCAACCCGAAGACCGGCGCCACCATCAAGATCCCGGCCGCACGTTCTCCGAAGTTCCGT
GCTGGCAAGGCACTGAAAGACGCGCTATAA

Upstream 100 bases:

>100_bases
ATGGCCGTGGAAGCCGCTTGACACAAGGATTTCCGCCTTGCTATAAAGCAAGCGTTTTTATCTGAACTACGTAGACCGAG
AACGACGAAAGGGGACTTAC

Downstream 100 bases:

>100_bases
TCAGCCCTTCCGTCGGGGCCTGATTCGTCGGGCCTCAGCGGGGCGCAAGGGCGTTTAGCTCAGTTGGTAGAGCGTCTGCC
TTACAAGCAGAATGTCGGCG

Product: DNA-binding protein HU-beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MNKSELIDAIAAEADISKAAAAKALDGMVAAVTSALKKGDTVTLVGFGTFYVGERAERSGRNPKTGATIKIPAARSPKFR
AGKALKDAL

Sequences:

>Translated_89_residues
MNKSELIDAIAAEADISKAAAAKALDGMVAAVTSALKKGDTVTLVGFGTFYVGERAERSGRNPKTGATIKIPAARSPKFR
AGKALKDAL
>Mature_89_residues
MNKSELIDAIAAEADISKAAAAKALDGMVAAVTSALKKGDTVTLVGFGTFYVGERAERSGRNPKTGATIKIPAARSPKFR
AGKALKDAL

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=69.6629213483146, Blast_Score=121, Evalue=8e-30,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=60.6741573033708, Blast_Score=110, Evalue=2e-26,
Organism=Escherichia coli, GI1787141, Length=88, Percent_Identity=37.5, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9149; Mature: 9149

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSELIDAIAAEADISKAAAAKALDGMVAAVTSALKKGDTVTLVGFGTFYVGERAERSG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCC
RNPKTGATIKIPAARSPKFRAGKALKDAL
CCCCCCCEEECCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure
MNKSELIDAIAAEADISKAAAAKALDGMVAAVTSALKKGDTVTLVGFGTFYVGERAERSG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCC
RNPKTGATIKIPAARSPKFRAGKALKDAL
CCCCCCCEEECCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]