Click here to switch to the map view.

The map label for this gene is vmrA [H]

Identifier: 34497910

GI number: 34497910

Start: 2640861

End: 2642204

Strand: Reverse

Name: vmrA [H]

Synonym: CV_2455

Alternate gene names: 34497910

Gene position: 2642204-2640861 (Counterclockwise)

Preceding gene: 34497912

Following gene: 34497909

Centisome position: 55.61

GC content: 68.6

Gene sequence:

>1344_bases
CTGGACCTCCTTCCCGTCTCCACCTTGTTCTGGCGCTACGCCATTCCCTCGATCGCCGGCATGCTGGTGACCGGCCTTTA
CGCCGTGATAGACGGGGTTTTCGTCGGCCATTACGTGGGCAGCCACGGCCTGGCCGCGATCAATCTCGCCTATCCGCTGG
TGATGCTGCAAGTGGGGCTGGGCGCGATGATCAGCATGGGCGCCGCCACCCGCATAGCCATCCAGCAAGGCGCCGGCGAC
ATGCGCGCCGCGCGCGGCACCCTGCTGACGGCGCTGGCGCTGCTGCTCTTGCTGAGCGCGCTGATCCCCGCGCTGGGCCT
GCCCAATATCGATCTGCTGCTGGCCTGGCTGAAGGCCGACGTCCAGCCTCAGGTGGCGGAGCAGGCGCGCGATTACCTAT
TGCTGATGCTGGCTGGCGCCGGGCTGACCATGGGGCCGATGCTGCTGACCTATCTGGTGCGCAACGACGGGCGGCCCAAG
CTGTCCACCGCGCTGATGACGCTGGGCGCCTTGTTGAACATTGGCCTGGATTACCTGTTCGTCGGCGTGATGGGCAAGGG
GCTGGCCGGCGCGGCCATCGGCACCTTGCTGGCGGAAGCCGTGGTCTTGATCCTGGCCTTGGCTTACTTTCTCAGTCCGC
GCGCCTCGCTGCGCATCCGCGCGGACCGGCTGCGGCCCGACTGGCGGGGCTTGTGGCCCATCCTGGCGCTGGGCGCGCCC
AGCCTGCTGATGGAGCTCAATCTGGCGCTGTTGCTGTATGCCCATAACCATCAGCTGCTGGTGTGGGGCAACGACCTGAG
CGTGGCCGCCTACGCGGTGGCCGGCTACAGCGAGTCCCTGTTCACCCTGGTGATCCACGGCCTGGCCGTGGGCATGCAGC
CGCTGCTGGGACATGCCATAGGCGCCGGCCAGGCCGAACGCGCGCGGGATGCGCTGCGGCACGGCGTCAAAGTGGGCCTG
ATCATCGGCGTCGCCGCATGGGCGGCGGTACAGCTGTTCCCGGCCTGGATCGCCGGCTGGTATAGCGACGGCAGCGCGGC
GCTGGTGGAGGAGGGCAGCCGCGCGCTGCGCCTGCATCTGCTGGCCATGCCTTTGGACGGTCTGGTCATCGTCGGCACCA
CGGCCTTGCAGGCGATGGCGCTGACCCGCTTGGCGCTGGGGGTGACGGTGGGCAAGACCGCGCTGCTGTTGCCCGCCTTG
GGCCTGCTGCCGCTGGCCATGGGTTTGGATGGCGTCTGGCTGGCGATGCCGCTGGTGAACCTGCTGCTGGGCACGGCGGT
GGCGCTGCTGTTGTGGCGGCAGTTCGGCCAGTTGCGGGGACGTTCGCTTGCCGCGCAAGCATGA

Upstream 100 bases:

>100_bases
ATTTAATCAATCATGCATGATTAATTAAATGCTAGAATGGTCTTTCCCATCGCTCTTTGCCGCAGCGCATATGCAGAATA
CCAATACGCACATCCGTGAC

Downstream 100 bases:

>100_bases
TGCGGGGAAATGCGATTTGATTTATGTCATATTGATATCTCGGATCCTGGATTGGGGAAGACGATATGGCGCATTTCGAG
CAGGAACACCATCTGGAAAT

Product: cation (Na+-coupled) multidrug resistance efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MDLLPVSTLFWRYAIPSIAGMLVTGLYAVIDGVFVGHYVGSHGLAAINLAYPLVMLQVGLGAMISMGAATRIAIQQGAGD
MRAARGTLLTALALLLLLSALIPALGLPNIDLLLAWLKADVQPQVAEQARDYLLLMLAGAGLTMGPMLLTYLVRNDGRPK
LSTALMTLGALLNIGLDYLFVGVMGKGLAGAAIGTLLAEAVVLILALAYFLSPRASLRIRADRLRPDWRGLWPILALGAP
SLLMELNLALLLYAHNHQLLVWGNDLSVAAYAVAGYSESLFTLVIHGLAVGMQPLLGHAIGAGQAERARDALRHGVKVGL
IIGVAAWAAVQLFPAWIAGWYSDGSAALVEEGSRALRLHLLAMPLDGLVIVGTTALQAMALTRLALGVTVGKTALLLPAL
GLLPLAMGLDGVWLAMPLVNLLLGTAVALLLWRQFGQLRGRSLAAQA

Sequences:

>Translated_447_residues
MDLLPVSTLFWRYAIPSIAGMLVTGLYAVIDGVFVGHYVGSHGLAAINLAYPLVMLQVGLGAMISMGAATRIAIQQGAGD
MRAARGTLLTALALLLLLSALIPALGLPNIDLLLAWLKADVQPQVAEQARDYLLLMLAGAGLTMGPMLLTYLVRNDGRPK
LSTALMTLGALLNIGLDYLFVGVMGKGLAGAAIGTLLAEAVVLILALAYFLSPRASLRIRADRLRPDWRGLWPILALGAP
SLLMELNLALLLYAHNHQLLVWGNDLSVAAYAVAGYSESLFTLVIHGLAVGMQPLLGHAIGAGQAERARDALRHGVKVGL
IIGVAAWAAVQLFPAWIAGWYSDGSAALVEEGSRALRLHLLAMPLDGLVIVGTTALQAMALTRLALGVTVGKTALLLPAL
GLLPLAMGLDGVWLAMPLVNLLLGTAVALLLWRQFGQLRGRSLAAQA
>Mature_447_residues
MDLLPVSTLFWRYAIPSIAGMLVTGLYAVIDGVFVGHYVGSHGLAAINLAYPLVMLQVGLGAMISMGAATRIAIQQGAGD
MRAARGTLLTALALLLLLSALIPALGLPNIDLLLAWLKADVQPQVAEQARDYLLLMLAGAGLTMGPMLLTYLVRNDGRPK
LSTALMTLGALLNIGLDYLFVGVMGKGLAGAAIGTLLAEAVVLILALAYFLSPRASLRIRADRLRPDWRGLWPILALGAP
SLLMELNLALLLYAHNHQLLVWGNDLSVAAYAVAGYSESLFTLVIHGLAVGMQPLLGHAIGAGQAERARDALRHGVKVGL
IIGVAAWAAVQLFPAWIAGWYSDGSAALVEEGSRALRLHLLAMPLDGLVIVGTTALQAMALTRLALGVTVGKTALLLPAL
GLLPLAMGLDGVWLAMPLVNLLLGTAVALLLWRQFGQLRGRSLAAQA

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46951; Mature: 46951

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLPVSTLFWRYAIPSIAGMLVTGLYAVIDGVFVGHYVGSHGLAAINLAYPLVMLQVGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GAMISMGAATRIAIQQGAGDMRAARGTLLTALALLLLLSALIPALGLPNIDLLLAWLKAD
HHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
VQPQVAEQARDYLLLMLAGAGLTMGPMLLTYLVRNDGRPKLSTALMTLGALLNIGLDYLF
CCHHHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VGVMGKGLAGAAIGTLLAEAVVLILALAYFLSPRASLRIRADRLRPDWRGLWPILALGAP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHCCH
SLLMELNLALLLYAHNHQLLVWGNDLSVAAYAVAGYSESLFTLVIHGLAVGMQPLLGHAI
HHHHHHHHHHEEEECCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GAGQAERARDALRHGVKVGLIIGVAAWAAVQLFPAWIAGWYSDGSAALVEEGSRALRLHL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHEEHEE
LAMPLDGLVIVGTTALQAMALTRLALGVTVGKTALLLPALGLLPLAMGLDGVWLAMPLVN
EEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LLLGTAVALLLWRQFGQLRGRSLAAQA
HHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDLLPVSTLFWRYAIPSIAGMLVTGLYAVIDGVFVGHYVGSHGLAAINLAYPLVMLQVGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GAMISMGAATRIAIQQGAGDMRAARGTLLTALALLLLLSALIPALGLPNIDLLLAWLKAD
HHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
VQPQVAEQARDYLLLMLAGAGLTMGPMLLTYLVRNDGRPKLSTALMTLGALLNIGLDYLF
CCHHHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VGVMGKGLAGAAIGTLLAEAVVLILALAYFLSPRASLRIRADRLRPDWRGLWPILALGAP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHCCH
SLLMELNLALLLYAHNHQLLVWGNDLSVAAYAVAGYSESLFTLVIHGLAVGMQPLLGHAI
HHHHHHHHHHEEEECCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GAGQAERARDALRHGVKVGLIIGVAAWAAVQLFPAWIAGWYSDGSAALVEEGSRALRLHL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHEEHEE
LAMPLDGLVIVGTTALQAMALTRLALGVTVGKTALLLPALGLLPLAMGLDGVWLAMPLVN
EEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LLLGTAVALLLWRQFGQLRGRSLAAQA
HHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA