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The map label for this gene is prgH [H]

Identifier: 34497878

GI number: 34497878

Start: 2606511

End: 2607686

Strand: Reverse

Name: prgH [H]

Synonym: CV_2423

Alternate gene names: 34497878

Gene position: 2607686-2606511 (Counterclockwise)

Preceding gene: 34497879

Following gene: 34497877

Centisome position: 54.89

GC content: 67.09

Gene sequence:

>1176_bases
GTGGAAGACATCAACACCTCTGGACGCGACGCCGTCGTCGTCCGCCTGCTCAATAGCCCGCTGCGCGGATGCGAGTTCAC
GCTGCAACCCGGAAAGACTCTGTTCCTGGTTGGGCCCGAGTCCGCGCTGGCCGCGGATGGGCTGCCGCCGGAGCTTCCGG
CGGACAGCCTATTCGTGCCGCTGGCTGAGGGTGGCGTCAACTTCGAGCTGCTGCTGGACAACGGCTGCGCCCGGCTGAGG
ATTCTCGGGGATGAGGTGACGGAAAGCGAGGCGCCGTTCAACCAGCCGCTGTCAGTGGGCGCCTTGCGACTCGCGTTGCG
GCCCCAGCATCTGCCGTGGCAGGCCGAGATCCTGAACGGCTTCGAACCGACCGGAGCGCCCGCGGCGCCATCTTCTGCGA
CCCCGGGCCGCGCCGGCCGCGCCCTGCTCGCGCTCGGTGCCTTGTGCGCCGTCGCACTGCTGGCCGCAGGAGGGCATTGG
CTGTGGAACAGCCAGCAGAGACAGGTGGCCGAGCTGAGCGCGCTGCTGGGCGACGATGGGCAGCGCTTCCATGTGCTGCC
GGGACGGGACGGCGTCTATTACGTCGCCGCCGCCGACGCCCGCGACGGCGTCTGGGCCAGGCAATCGTTATTGCGAGCCG
AATTCCGCCAGCCGGTCCAGATCGTGGAGCCGGCCGGCGAAAGCGAGCGCGTGTCCCGCTGGCTGTCCGAAAGCCGGCCC
GAATTGGCCTTTTACAGGCTGTTGTTGGACGACCCGCGCCGGCCGCAGCTGTGGATCAGCCGCCAGCGATCGCCGCTGGA
TGAAGCCTCCAGGCAGAAGCTGGCCAGCCAGCTGTCGGTACTGATGCCTTACGCCGAGCGCGTATCCATCGTGCCGGTGG
ACGACGAGGCCGCCTCCCGGCAGGCCGAGGAAGGGCTGAGCCGCCAGGCGCTGCCGTTTACCCGCAACGATCAGCGCGAC
AGCGTCACATTCGTGATCGCCGGCGCGCTCGACGACGGCGAGCTGCAGCGGGCGCGGCAATTCGTCGATGCCTACTATCG
CCAATGGGGCGGACGCTATGTGCAGTTCGCCATCGAGTTGAAGGATGACTGGCTCAAGGGCAAGTCCTTCAAATATGGAA
GCCAGGGCTATGTGAAGCTGAACAGCGGCCATTGGTATTTCCCCAAACCCCTCTGA

Upstream 100 bases:

>100_bases
TTTGATCGGCTTTTCATCAGGAACTGTTGCCATCGCGCCGCTACAGTGCCCACATGCCCGGCCCCGCCGGCAAGCACCTG
ATCCGGAAGACGATATCACC

Downstream 100 bases:

>100_bases
CCGAAAGGAACCACAGACATGCCAGACCCGGTGAATACCCCATGGAGCGGTTATCTGGATGGCGTTTCCAACCAATTCGA
CCAAGGCGTGCAGGATCTGC

Product: pathogenicity 1 island effector protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MEDINTSGRDAVVVRLLNSPLRGCEFTLQPGKTLFLVGPESALAADGLPPELPADSLFVPLAEGGVNFELLLDNGCARLR
ILGDEVTESEAPFNQPLSVGALRLALRPQHLPWQAEILNGFEPTGAPAAPSSATPGRAGRALLALGALCAVALLAAGGHW
LWNSQQRQVAELSALLGDDGQRFHVLPGRDGVYYVAAADARDGVWARQSLLRAEFRQPVQIVEPAGESERVSRWLSESRP
ELAFYRLLLDDPRRPQLWISRQRSPLDEASRQKLASQLSVLMPYAERVSIVPVDDEAASRQAEEGLSRQALPFTRNDQRD
SVTFVIAGALDDGELQRARQFVDAYYRQWGGRYVQFAIELKDDWLKGKSFKYGSQGYVKLNSGHWYFPKPL

Sequences:

>Translated_391_residues
MEDINTSGRDAVVVRLLNSPLRGCEFTLQPGKTLFLVGPESALAADGLPPELPADSLFVPLAEGGVNFELLLDNGCARLR
ILGDEVTESEAPFNQPLSVGALRLALRPQHLPWQAEILNGFEPTGAPAAPSSATPGRAGRALLALGALCAVALLAAGGHW
LWNSQQRQVAELSALLGDDGQRFHVLPGRDGVYYVAAADARDGVWARQSLLRAEFRQPVQIVEPAGESERVSRWLSESRP
ELAFYRLLLDDPRRPQLWISRQRSPLDEASRQKLASQLSVLMPYAERVSIVPVDDEAASRQAEEGLSRQALPFTRNDQRD
SVTFVIAGALDDGELQRARQFVDAYYRQWGGRYVQFAIELKDDWLKGKSFKYGSQGYVKLNSGHWYFPKPL
>Mature_391_residues
MEDINTSGRDAVVVRLLNSPLRGCEFTLQPGKTLFLVGPESALAADGLPPELPADSLFVPLAEGGVNFELLLDNGCARLR
ILGDEVTESEAPFNQPLSVGALRLALRPQHLPWQAEILNGFEPTGAPAAPSSATPGRAGRALLALGALCAVALLAAGGHW
LWNSQQRQVAELSALLGDDGQRFHVLPGRDGVYYVAAADARDGVWARQSLLRAEFRQPVQIVEPAGESERVSRWLSESRP
ELAFYRLLLDDPRRPQLWISRQRSPLDEASRQKLASQLSVLMPYAERVSIVPVDDEAASRQAEEGLSRQALPFTRNDQRD
SVTFVIAGALDDGELQRARQFVDAYYRQWGGRYVQFAIELKDDWLKGKSFKYGSQGYVKLNSGHWYFPKPL

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013387
- InterPro:   IPR019029 [H]

Pfam domain/function: PF09480 PrgH [H]

EC number: NA

Molecular weight: Translated: 43125; Mature: 43125

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDINTSGRDAVVVRLLNSPLRGCEFTLQPGKTLFLVGPESALAADGLPPELPADSLFVP
CCCCCCCCCHHHHHEECCCCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCCCCCCEEEE
LAEGGVNFELLLDNGCARLRILGDEVTESEAPFNQPLSVGALRLALRPQHLPWQAEILNG
ECCCCCEEEEEECCCCEEEEEECCHHCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHCC
FEPTGAPAAPSSATPGRAGRALLALGALCAVALLAAGGHWLWNSQQRQVAELSALLGDDG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCC
QRFHVLPGRDGVYYVAAADARDGVWARQSLLRAEFRQPVQIVEPAGESERVSRWLSESRP
CEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCC
ELAFYRLLLDDPRRPQLWISRQRSPLDEASRQKLASQLSVLMPYAERVSIVPVDDEAASR
HHEEHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHCEEEEECCCHHHHH
QAEEGLSRQALPFTRNDQRDSVTFVIAGALDDGELQRARQFVDAYYRQWGGRYVQFAIEL
HHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEE
KDDWLKGKSFKYGSQGYVKLNSGHWYFPKPL
CCCCCCCCCCCCCCCCEEEECCCCEECCCCC
>Mature Secondary Structure
MEDINTSGRDAVVVRLLNSPLRGCEFTLQPGKTLFLVGPESALAADGLPPELPADSLFVP
CCCCCCCCCHHHHHEECCCCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCCCCCCEEEE
LAEGGVNFELLLDNGCARLRILGDEVTESEAPFNQPLSVGALRLALRPQHLPWQAEILNG
ECCCCCEEEEEECCCCEEEEEECCHHCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHCC
FEPTGAPAAPSSATPGRAGRALLALGALCAVALLAAGGHWLWNSQQRQVAELSALLGDDG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCC
QRFHVLPGRDGVYYVAAADARDGVWARQSLLRAEFRQPVQIVEPAGESERVSRWLSESRP
CEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCC
ELAFYRLLLDDPRRPQLWISRQRSPLDEASRQKLASQLSVLMPYAERVSIVPVDDEAASR
HHEEHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHCEEEEECCCHHHHH
QAEEGLSRQALPFTRNDQRDSVTFVIAGALDDGELQRARQFVDAYYRQWGGRYVQFAIEL
HHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEE
KDDWLKGKSFKYGSQGYVKLNSGHWYFPKPL
CCCCCCCCCCCCCCCCEEEECCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]