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The map label for this gene is ppa [H]

Identifier: 33863543

GI number: 33863543

Start: 1363572

End: 1364159

Strand: Reverse

Name: ppa [H]

Synonym: PMT1275

Alternate gene names: 33863543

Gene position: 1364159-1363572 (Counterclockwise)

Preceding gene: 33863544

Following gene: 33863542

Centisome position: 56.58

GC content: 52.72

Gene sequence:

>588_bases
ATGGCCAACATCGATCAGGCTCCAAGCCGCAGCACTCCCAACCTCTTGCATGTGTTGCCTGCCTTTGCCGATGAATCGGA
ATTGCGGCTCAACACGATCGTGGAGCTCAACTCCAACACGATCAATAAATATGAGCTGATCACGGAAACAGGCCACCTCA
AGCTTGATCGTGTCGGCTATTCCTCCCTGGCCTATCCCTTTGCCTACGGTTGCATTCCTCGTACATGGGACGAAGACGGT
GATCCACTCGACATCGAAATCGTCAGTGTCACAGAGCCGCTGGTGCCCGGCTCGATTGTTGAGGCAAGGATCATTGGCAT
CATGACCTTTGATGATGGTGGTGAAGTCGACGACAAAGTGATCGCTGTGCTGGCTGATGACAAGCGCATGGACCACATCA
CCAGCTTTGAACAGCTCGGAGAGCAATGGCTGAAGGAGACCCAGTACTACTGGGAGCACTACAAGGACCTTAAAAAGCCT
GGTACCTGCAGGGTGAACGGCTTCTTAGGGGTGCAAAAGGCTGTCGAGATTATCAAGGCCTGCGAAGCCCGTTATCTCGC
TGAGATCGATCCAAAACTGGTTGATTGA

Upstream 100 bases:

>100_bases
GTTAAGCATCGTTTATTGAATCAATCGCTTTGGATTCTTTGCGGCGATGAGCTTGATCGCGGCGCCCCCGTAGGATGCGC
CGCTGGCGACTTCGCTACTT

Downstream 100 bases:

>100_bases
TCCTTGCGGCAATGGTCGTTGGCAGCGAATGAACATGGCCTGAACGGTTTTGTTGCTCGCTGTTTATCTTGAGACTGATC
AGTCTTTGCTGGCCATGTCA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MANIDQAPSRSTPNLLHVLPAFADESELRLNTIVELNSNTINKYELITETGHLKLDRVGYSSLAYPFAYGCIPRTWDEDG
DPLDIEIVSVTEPLVPGSIVEARIIGIMTFDDGGEVDDKVIAVLADDKRMDHITSFEQLGEQWLKETQYYWEHYKDLKKP
GTCRVNGFLGVQKAVEIIKACEARYLAEIDPKLVD

Sequences:

>Translated_195_residues
MANIDQAPSRSTPNLLHVLPAFADESELRLNTIVELNSNTINKYELITETGHLKLDRVGYSSLAYPFAYGCIPRTWDEDG
DPLDIEIVSVTEPLVPGSIVEARIIGIMTFDDGGEVDDKVIAVLADDKRMDHITSFEQLGEQWLKETQYYWEHYKDLKKP
GTCRVNGFLGVQKAVEIIKACEARYLAEIDPKLVD
>Mature_194_residues
ANIDQAPSRSTPNLLHVLPAFADESELRLNTIVELNSNTINKYELITETGHLKLDRVGYSSLAYPFAYGCIPRTWDEDGD
PLDIEIVSVTEPLVPGSIVEARIIGIMTFDDGGEVDDKVIAVLADDKRMDHITSFEQLGEQWLKETQYYWEHYKDLKKPG
TCRVNGFLGVQKAVEIIKACEARYLAEIDPKLVD

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 21944; Mature: 21813

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIDQAPSRSTPNLLHVLPAFADESELRLNTIVELNSNTINKYELITETGHLKLDRVGY
CCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEEECCCCCCEEEEEECCCCEEEECCCC
SSLAYPFAYGCIPRTWDEDGDPLDIEIVSVTEPLVPGSIVEARIIGIMTFDDGGEVDDKV
CHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCEE
IAVLADDKRMDHITSFEQLGEQWLKETQYYWEHYKDLKKPGTCRVNGFLGVQKAVEIIKA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHH
CEARYLAEIDPKLVD
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANIDQAPSRSTPNLLHVLPAFADESELRLNTIVELNSNTINKYELITETGHLKLDRVGY
CCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEEECCCCCCEEEEEECCCCEEEECCCC
SSLAYPFAYGCIPRTWDEDGDPLDIEIVSVTEPLVPGSIVEARIIGIMTFDDGGEVDDKV
CHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCEE
IAVLADDKRMDHITSFEQLGEQWLKETQYYWEHYKDLKKPGTCRVNGFLGVQKAVEIIKA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHH
CEARYLAEIDPKLVD
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1963432 [H]