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The map label for this gene is csgA [H]

Identifier: 33863515

GI number: 33863515

Start: 1334739

End: 1335404

Strand: Reverse

Name: csgA [H]

Synonym: PMT1247

Alternate gene names: 33863515

Gene position: 1335404-1334739 (Counterclockwise)

Preceding gene: 33863516

Following gene: 33863508

Centisome position: 55.39

GC content: 50.3

Gene sequence:

>666_bases
TTGGCGACCTATCTGATCACAGGAACGAATCGCGGCATTGGCTATGAATATTGTCGTCAGCTTCATGCTCGTGGTGACGT
GGTTGTGGCTGCATGCCGTAAGCCTTCGCAGCAATTGGAAGGCTTAGGCGTGCGTATTGAGGCCGGAGTCGAGATCACTT
CAGATGGATCGATTGCGCGCTTGAAGCAACGGCTTCGCAGCTTGCCGATCGATGTACTGATCCACAATGCCGGCATTTTG
GAAAGCACGACTTTGAAAGATTTTGATCCCGAGAGCCTTCGTCGTCAGTTCGAGGTCAACGCCATTGGGCCATTACGTGT
CACACATGCTCTCATGGATCATCTACTTCCTGGCGCAAAAGTCATTTTGATGACTAGCCGAATGGGCTCGATCGATGACA
ACAGTTCCGGCGGTTCTTATGGCTACAGGATGTCGAAGGTGGCTTTGTGTATGGCAGGAAAGTCATTAGCTATCGACCTT
AAATCTCAAGGCATTGCCGTGGCGCTTCTTCATCCAGGGCTTGTGCGTACCCGCATGACAGGATTCACTGATCAAGGCAT
TACTCCAGAAGAATCGGTTGATGGCTTGTTGGCCCGTATTGACAATCTCAATTTGGAAAACTCAGGCACTTTTTGGCATG
CCAATGGGGAGATTCTCCCTTGGTAA

Upstream 100 bases:

>100_bases
AGATCAGGGCTGGCAATCCTGCCAATCCAACTGGCATGCGTGCAAAGATACTCTCTCGCTATAAAGTTATTTTCTAAATA
GGCTTCTGCTTTCTCTGCTC

Downstream 100 bases:

>100_bases
CAATTGGTTTTGTGAAGAAGTGATTGACGTTGCTTTGGGCCTGTGATTTTGCGTTCTTCGTAATCACTTGAGAGCACTTC
ACTGCTCACGCTGAAATTTA

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MATYLITGTNRGIGYEYCRQLHARGDVVVAACRKPSQQLEGLGVRIEAGVEITSDGSIARLKQRLRSLPIDVLIHNAGIL
ESTTLKDFDPESLRRQFEVNAIGPLRVTHALMDHLLPGAKVILMTSRMGSIDDNSSGGSYGYRMSKVALCMAGKSLAIDL
KSQGIAVALLHPGLVRTRMTGFTDQGITPEESVDGLLARIDNLNLENSGTFWHANGEILPW

Sequences:

>Translated_221_residues
MATYLITGTNRGIGYEYCRQLHARGDVVVAACRKPSQQLEGLGVRIEAGVEITSDGSIARLKQRLRSLPIDVLIHNAGIL
ESTTLKDFDPESLRRQFEVNAIGPLRVTHALMDHLLPGAKVILMTSRMGSIDDNSSGGSYGYRMSKVALCMAGKSLAIDL
KSQGIAVALLHPGLVRTRMTGFTDQGITPEESVDGLLARIDNLNLENSGTFWHANGEILPW
>Mature_220_residues
ATYLITGTNRGIGYEYCRQLHARGDVVVAACRKPSQQLEGLGVRIEAGVEITSDGSIARLKQRLRSLPIDVLIHNAGILE
STTLKDFDPESLRRQFEVNAIGPLRVTHALMDHLLPGAKVILMTSRMGSIDDNSSGGSYGYRMSKVALCMAGKSLAIDLK
SQGIAVALLHPGLVRTRMTGFTDQGITPEESVDGLLARIDNLNLENSGTFWHANGEILPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Escherichia coli, GI1786701, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1787335, Length=188, Percent_Identity=28.7234042553192, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI87082100, Length=199, Percent_Identity=27.6381909547739, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558996, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17558990, Length=247, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558992, Length=241, Percent_Identity=27.8008298755187, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559964, Length=245, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559962, Length=209, Percent_Identity=33.0143540669856, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72001658, Length=244, Percent_Identity=29.0983606557377, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558994, Length=241, Percent_Identity=26.5560165975104, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17542178, Length=240, Percent_Identity=31.6666666666667, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193207563, Length=241, Percent_Identity=24.896265560166, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558006, Length=202, Percent_Identity=28.2178217821782, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17541382, Length=254, Percent_Identity=30.7086614173228, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322779, Length=245, Percent_Identity=29.3877551020408, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640547, Length=249, Percent_Identity=29.718875502008, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24643142, Length=184, Percent_Identity=33.695652173913, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI23397609, Length=205, Percent_Identity=30.7317073170732, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24013; Mature: 23882

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYLITGTNRGIGYEYCRQLHARGDVVVAACRKPSQQLEGLGVRIEAGVEITSDGSIAR
CEEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHCCCCEEEECCEEEECCCCHHH
LKQRLRSLPIDVLIHNAGILESTTLKDFDPESLRRQFEVNAIGPLRVTHALMDHLLPGAK
HHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHEECCCCCCHHHHHHHHHHHHCCCCE
VILMTSRMGSIDDNSSGGSYGYRMSKVALCMAGKSLAIDLKSQGIAVALLHPGLVRTRMT
EEEEECCCCCCCCCCCCCCCCHHHHHEEHEECCCEEEEEECCCCEEEEEECCCHHHHHHC
GFTDQGITPEESVDGLLARIDNLNLENSGTFWHANGEILPW
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCEECC
>Mature Secondary Structure 
ATYLITGTNRGIGYEYCRQLHARGDVVVAACRKPSQQLEGLGVRIEAGVEITSDGSIAR
EEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHCCCCEEEECCEEEECCCCHHH
LKQRLRSLPIDVLIHNAGILESTTLKDFDPESLRRQFEVNAIGPLRVTHALMDHLLPGAK
HHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHEECCCCCCHHHHHHHHHHHHCCCCE
VILMTSRMGSIDDNSSGGSYGYRMSKVALCMAGKSLAIDLKSQGIAVALLHPGLVRTRMT
EEEEECCCCCCCCCCCCCCCCHHHHHEEHEECCCEEEEEECCCCEEEEEECCCHHHHHHC
GFTDQGITPEESVDGLLARIDNLNLENSGTFWHANGEILPW
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]