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The map label for this gene is tal

Identifier: 33863516

GI number: 33863516

Start: 1335673

End: 1336845

Strand: Reverse

Name: tal

Synonym: PMT1248

Alternate gene names: 33863516

Gene position: 1336845-1335673 (Counterclockwise)

Preceding gene: 33863517

Following gene: 33863515

Centisome position: 55.45

GC content: 47.66

Gene sequence:

>1173_bases
ATGGCCACACTCCTTGAGCAGCTTTCCACCATGACCGTGGTCGTGGCGGATACCGGTGATTTGGACGCGATTAGAAAGTT
CACCCCCAGGGATGCCACGACCAACCCTTCATTGATCCTTGCGGCGGCTCAGATTCCTGCTTATCAGAGTTTGATCGATG
AGGCTCTTCACTCCTCCCGTCAGTTATTGGGTAACTCTGCAGCTGTGGAGGAGGTGGTCCATGAGGCTCTCGATGAGATT
TGTGTAATCTTTGGAAAGGAAATTCTCAAGATTGTTCCTGGCCGTGTTTCCACTGAAGTGGATGCTCGTCTCAGTTTCAA
TACTGAAGCCACAATCGCTAAGGCTCACAAACTCATTGGCCTATATAACGACGCTGGCATTACTAATGATCGCGTTTTGA
TCAAGATAGCTTCTACTTGGGAGGGTATAAAAGCGGCTGAGGTTTTGGAGAAGGATGGAATTCATTGCAATTTAACTCTG
CTATTTGGCTTTTCTCAGGCTGTCGCTTGTGCAGAAGCAGGAGTCACTTTGATCTCTCCTTTTGTTGGGCGAATCCTTGA
TTGGTACAAAGCGTCTACTGGTCGGGATTCTTATGCAGGTCCAGAAGACCCTGGTGTGATCTCGGTGACCAAGATCTTTA
ATTATTTCAAAACCTATGATTACAAGACTGAGATCATGGGTGCGAGTTTCCGCAATCTTGACGAAATCATTGAATTGGCT
GGATGTGATTTGTTGACCATCTCACCAAAGCTTTTGGATCAGCTGGGTAGTACAGAGGCTCCGCTGAAGCGTAAGTTGGA
TGCGGTTAATCCTGTTGCTGCAGAGTCTCAGATCCATGTCGATAAGGAGAGTTTTGAGTCAATGATGAGGGCTGATCGCA
TGGCTTTTGAGAAGTTGGATGAAGGGATTCGCGGCTTTAGCAAGGCGATTGAAACTCTTGAGGCTCAGCTGGCGCATCGA
TTAGCTGTTTTGGAGGGAGGAGCGGCCTTCTGCCATGTTGTTCAGGAGATTTTCATGCTCAATGATCTCGATGGTGATGG
TTGTATTACTAGAGAAGAATGGCTCGGTAGTGATGCGGTATTTGATGCCTTAGATCATGACCATGATGGCCGACTTCTTC
AGGAAGATGTTCGTTCCGGGCTGGGTGCTGCTTTGGCACTAACAACAGCTTGA

Upstream 100 bases:

>100_bases
AAGGCTAAGTCTTGGCAAATCTTCGATGGTGAGTTCTGAACCTGGGCTGTCAGCAAAAAAAACGCCGCTAGCTTAAAGAT
CTTGCGAGACGTTCTGCTTC

Downstream 100 bases:

>100_bases
AGTCTTGCTTAGTAAGTTAATAAGGTGATGAGTATTTATCATCATTCCTTATAATGTTGAAAAATACTCTGCTTTGCCTG
AGTTGAAGCTGGAGAGTTTT

Product: transaldolase/EF-hand domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSRQLLGNSAAVEEVVHEALDEI
CVIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIGLYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTL
LFGFSQAVACAEAGVTLISPFVGRILDWYKASTGRDSYAGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELA
GCDLLTISPKLLDQLGSTEAPLKRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLDEGIRGFSKAIETLEAQLAHR
LAVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAVFDALDHDHDGRLLQEDVRSGLGAALALTTA

Sequences:

>Translated_390_residues
MATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSRQLLGNSAAVEEVVHEALDEI
CVIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIGLYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTL
LFGFSQAVACAEAGVTLISPFVGRILDWYKASTGRDSYAGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELA
GCDLLTISPKLLDQLGSTEAPLKRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLDEGIRGFSKAIETLEAQLAHR
LAVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAVFDALDHDHDGRLLQEDVRSGLGAALALTTA
>Mature_389_residues
ATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSRQLLGNSAAVEEVVHEALDEIC
VIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIGLYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTLL
FGFSQAVACAEAGVTLISPFVGRILDWYKASTGRDSYAGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELAG
CDLLTISPKLLDQLGSTEAPLKRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLDEGIRGFSKAIETLEAQLAHRL
AVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAVFDALDHDHDGRLLQEDVRSGLGAALALTTA

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 EF-hand domains

Homologues:

Organism=Homo sapiens, GI5803187, Length=329, Percent_Identity=57.4468085106383, Blast_Score=369, Evalue=1e-102,
Organism=Escherichia coli, GI1786189, Length=321, Percent_Identity=56.6978193146417, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1788807, Length=317, Percent_Identity=52.3659305993691, Blast_Score=315, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI25153750, Length=321, Percent_Identity=55.7632398753894, Blast_Score=352, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI25153752, Length=165, Percent_Identity=54.5454545454545, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17570473, Length=97, Percent_Identity=46.3917525773196, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323386, Length=317, Percent_Identity=61.5141955835962, Blast_Score=333, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6321480, Length=316, Percent_Identity=54.4303797468354, Blast_Score=323, Evalue=3e-89,
Organism=Drosophila melanogaster, GI45549185, Length=316, Percent_Identity=55.0632911392405, Blast_Score=349, Evalue=2e-96,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): TAL_PROMM (Q7V6B8)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_895076.1
- ProteinModelPortal:   Q7V6B8
- SMR:   Q7V6B8
- STRING:   Q7V6B8
- GeneID:   1728706
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT1248
- NMPDR:   fig|74547.1.peg.1243
- eggNOG:   COG0176
- HOGENOM:   HBG286747
- OMA:   DTGDFHA
- ProtClustDB:   PRK12309
- BioCyc:   PMAR74547:PMT1248-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00492
- InterPro:   IPR013785
- InterPro:   IPR011992
- InterPro:   IPR018247
- InterPro:   IPR018249
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- Gene3D:   G3DSA:1.10.238.10
- PANTHER:   PTHR10683
- PANTHER:   PTHR10683:SF3
- TIGRFAMs:   TIGR00874

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 42359; Mature: 42227

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00018 EF_HAND_1; PS50222 EF_HAND_2; PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSR
CCHHHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHH
QLLGNSAAVEEVVHEALDEICVIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHE
LYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTLLFGFSQAVACAEAGVTLISP
EECCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHCCHHHHHH
FVGRILDWYKASTGRDSYAGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELA
HHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHCCCHHCCHHHHHHHH
GCDLLTISPKLLDQLGSTEAPLKRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLD
CCCEEEECHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
EGIRGFSKAIETLEAQLAHRLAVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHH
FDALDHDHDGRLLQEDVRSGLGAALALTTA
HHHHCCCCCCCHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
ATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSR
CHHHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHH
QLLGNSAAVEEVVHEALDEICVIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHE
LYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTLLFGFSQAVACAEAGVTLISP
EECCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHCCHHHHHH
FVGRILDWYKASTGRDSYAGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELA
HHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHCCCHHCCHHHHHHHH
GCDLLTISPKLLDQLGSTEAPLKRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLD
CCCEEEECHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
EGIRGFSKAIETLEAQLAHRLAVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHH
FDALDHDHDGRLLQEDVRSGLGAALALTTA
HHHHCCCCCCCHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642