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The map label for this gene is tldD [C]

Identifier: 33863042

GI number: 33863042

Start: 839297

End: 840742

Strand: Direct

Name: tldD [C]

Synonym: PMT0770

Alternate gene names: 33863042

Gene position: 839297-840742 (Clockwise)

Preceding gene: 33863041

Following gene: 33863043

Centisome position: 34.81

GC content: 53.18

Gene sequence:

>1446_bases
TTGGTCTCGACCTACACCCCAGATCAAAGCCTGGTGCATAAGGCAGAAGCCTTGAATAGCCACTGGCAACCACAACTGGA
ATTACTACTAGCGCGTGGTCGAACTGCCGGTGCTGATCTGGTGGAGGTCTACCTGGAGCAAATTGATCATCTCAGCGTCC
TTGCTGAACAAGACACCATTACCAGTGTCACTCCATCCTTCGGCAGGGGTGCTGGGATCAGGGTGTTCCTGGGCAAACAA
GATGGCTTTGTCAGTACCAATGATCTTTCAGATGCAGGCCTGAAGCATGCATTAGAGCAAGCTCTCAGCATGCTTGGGCT
TGAGGTTAATGAGGCTGGTCGCTCATCATTTAATGGTCTGCCGAACCTTCGTGATTTCGCCATCGATAAGGCCGACTGGC
TCAACCAATGCCCAGAGCTGTATGAAGCAAGTGATCGCCTTCTAAATGGAACTCAATTGCTTAATCAATATGGAACCCAT
CTGCAGGTGCGGCGAGGCAGTTATGCCCGCGACTGGCAGGAGGTTCTCGTGGCTGCAAGTGATGGCACCTTTGGACGCGA
CATCCGTTTGCATCAGTCCATAGGACTTAATGTCCTTGCTACAGATGGCGAGCACCGCTCAAGCATTGGTCGCCGTTATG
GCACATCGGGACGTCCAGACGATCTTCGCAAGTGGGATGCCGAAACGAGCGCCAAGGAAGTTTGCGAAAGCGCAGGCACG
ATGCTTTATGCCGATTACGTGGACGCCGGTCAAATGCCAGCAGTACTCGCCAACCGCTTTGGTGGTGTGATTTTTCACGA
AGCATGTGGGCATTTGCTCGAGACCACTCAGATCGAGCGCGGTACAACACCTTTCAGCGAGAAGTTGAACCAATCGATCG
CCCATGAAGCTGTAACGGCAATCGATGAGGGGATTACTGATGGGGCCTTCGGTTCCCTGAGCATGGATGACGAAGGCATG
GAAAGTCAGCGAACGGTATTAATTGAAAACGGTGTGCTCAAGCAATTCATCAGCGATAGAGCCGGTGAGCTCCGTACCGG
TCACCAGCGCACAGGCAGCGGCCGACGTCAGTCCCACACATTCGCTGCAGCTAGCCGCATGCGCAACACTTATATCGCCG
CCGGCCAGCACTCACCGGAACAACTCATCGCCTCGATCGACCGAGGCCTTTACTGCAAATCAATGGGTGGAGGCAGCGTT
GGACCCACAGGTCAATTTAATTTTGCTGTAGAAGAGGGCTATCTGATCGAGAAAGGCAAGCTCGGCAAACCTGTTAAAGG
AGCCACTCTGATTGGCGAAGCAAAGGATGTGATGCCACGGATCTCGATGTGTGCCAAGGATCTTGAGCTGGCAGCCGGTT
TCTGCGGGTCAATAAGCGGTAACATTTTTGTCACCGTAGGGCAGCCTCATATCAAAGTCGATTCAATCACCGTGGGAGGG
CGTTGA

Upstream 100 bases:

>100_bases
GAAATAAGCATTTTTTTTGCGGTTCGCCTGGATCGGCGCTGTCCATCTACATATCTACGCAAATTCTCTCCATAATCAAC
GCAAGCTGCAGGAGAAATGG

Downstream 100 bases:

>100_bases
TGATGTCCGAAATACAAGCAGCAAATGCAATCGAACTCGACACTCATTCTCTACGGGATAAACTCAGTCAACTTGCTAGC
CGCGAGAGTATCCACCAATG

Product: modulator of DNA gyrase; TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVSTYTPDQSLVHKAEALNSHWQPQLELLLARGRTAGADLVEVYLEQIDHLSVLAEQDTITSVTPSFGRGAGIRVFLGKQ
DGFVSTNDLSDAGLKHALEQALSMLGLEVNEAGRSSFNGLPNLRDFAIDKADWLNQCPELYEASDRLLNGTQLLNQYGTH
LQVRRGSYARDWQEVLVAASDGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRKWDAETSAKEVCESAGT
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSEKLNQSIAHEAVTAIDEGITDGAFGSLSMDDEGM
ESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQSHTFAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSV
GPTGQFNFAVEEGYLIEKGKLGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
R

Sequences:

>Translated_481_residues
MVSTYTPDQSLVHKAEALNSHWQPQLELLLARGRTAGADLVEVYLEQIDHLSVLAEQDTITSVTPSFGRGAGIRVFLGKQ
DGFVSTNDLSDAGLKHALEQALSMLGLEVNEAGRSSFNGLPNLRDFAIDKADWLNQCPELYEASDRLLNGTQLLNQYGTH
LQVRRGSYARDWQEVLVAASDGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRKWDAETSAKEVCESAGT
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSEKLNQSIAHEAVTAIDEGITDGAFGSLSMDDEGM
ESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQSHTFAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSV
GPTGQFNFAVEEGYLIEKGKLGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
R
>Mature_481_residues
MVSTYTPDQSLVHKAEALNSHWQPQLELLLARGRTAGADLVEVYLEQIDHLSVLAEQDTITSVTPSFGRGAGIRVFLGKQ
DGFVSTNDLSDAGLKHALEQALSMLGLEVNEAGRSSFNGLPNLRDFAIDKADWLNQCPELYEASDRLLNGTQLLNQYGTH
LQVRRGSYARDWQEVLVAASDGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRKWDAETSAKEVCESAGT
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSEKLNQSIAHEAVTAIDEGITDGAFGSLSMDDEGM
ESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQSHTFAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSV
GPTGQFNFAVEEGYLIEKGKLGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
R

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=450, Percent_Identity=34.2222222222222, Blast_Score=222, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51991; Mature: 51991

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTYTPDQSLVHKAEALNSHWQPQLELLLARGRTAGADLVEVYLEQIDHLSVLAEQDTI
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
TSVTPSFGRGAGIRVFLGKQDGFVSTNDLSDAGLKHALEQALSMLGLEVNEAGRSSFNGL
CCCCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCHHCCHHCCCC
PNLRDFAIDKADWLNQCPELYEASDRLLNGTQLLNQYGTHLQVRRGSYARDWQEVLVAAS
CCHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHEECC
DGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRKWDAETSAKEVCESAGT
CCCCCCCEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCC
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSEKLNQSIAHEAVTA
EEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IDEGITDGAFGSLSMDDEGMESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQSHT
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
FAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSVGPTGQFNFAVEEGYLIEKGK
HHHHHHHCCCEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEECCCEEEECCC
LGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEECCC
R
C
>Mature Secondary Structure
MVSTYTPDQSLVHKAEALNSHWQPQLELLLARGRTAGADLVEVYLEQIDHLSVLAEQDTI
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
TSVTPSFGRGAGIRVFLGKQDGFVSTNDLSDAGLKHALEQALSMLGLEVNEAGRSSFNGL
CCCCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCHHCCHHCCCC
PNLRDFAIDKADWLNQCPELYEASDRLLNGTQLLNQYGTHLQVRRGSYARDWQEVLVAAS
CCHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHEECC
DGTFGRDIRLHQSIGLNVLATDGEHRSSIGRRYGTSGRPDDLRKWDAETSAKEVCESAGT
CCCCCCCEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCC
MLYADYVDAGQMPAVLANRFGGVIFHEACGHLLETTQIERGTTPFSEKLNQSIAHEAVTA
EEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IDEGITDGAFGSLSMDDEGMESQRTVLIENGVLKQFISDRAGELRTGHQRTGSGRRQSHT
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
FAAASRMRNTYIAAGQHSPEQLIASIDRGLYCKSMGGGSVGPTGQFNFAVEEGYLIEKGK
HHHHHHHCCCEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEECCCEEEECCC
LGKPVKGATLIGEAKDVMPRISMCAKDLELAAGFCGSISGNIFVTVGQPHIKVDSITVGG
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEECCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]