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The map label for this gene is pmbA [C]

Identifier: 33863043

GI number: 33863043

Start: 840742

End: 842130

Strand: Direct

Name: pmbA [C]

Synonym: PMT0771

Alternate gene names: 33863043

Gene position: 840742-842130 (Clockwise)

Preceding gene: 33863042

Following gene: 33863044

Centisome position: 34.87

GC content: 47.44

Gene sequence:

>1389_bases
ATGATGTCCGAAATACAAGCAGCAAATGCAATCGAACTCGACACTCATTCTCTACGGGATAAACTCAGTCAACTTGCTAG
CCGCGAGAGTATCCACCAATGGGATTTAGGAGCATCATGCAGCACAGATAGTTCTGTTCAAATTGATCGTGGCGAAGCCA
AGCAAATGAAGGGTGCGCAACGCAGCTCAATCACAGTACGTGTATGGAACAACAAAGGGCTTGTAGGAATCACAAGCACG
TCAGATCTTTCAGAAAAAGGAATAGAGAAAGCGCTTATTGGTGCTCGTCAGGCAAGTGACTTTGGCAACGCCGATGACGT
TCCTGCCTTCTCAACACTCGCTAAATCTCCGTTACCAAAGCTAGAGCGACCTCTAAGACCAGCACAGGGAATTCAACGAA
TGCTTGAGGTTCTTAAAGAGGCCGAAGCTGATCTTCTTAGTCGACATCCTGCTATACAGAGCATTCCTTACAACGGTCTA
GGAGAAGCAACCTACGAACGAGTTTATCTCAATAGCGATGGTGCGCTTCGTCAAATGAAGCGTAGTCAAGCCAGCCTTTA
CCTTTTTGCCCGCGCAGAAGAAAGTGGACGTAAACCACGCAGTGGTGGTGCAATTCGCCTTGCTCTAGGTAGTCACGATC
TGGATATTGATGGATGTATTGATGAAGCAGCAGAACGAACAATCAGTCATCTTGACTATCAGCCGATCGACACTGGGTGT
TATCTCGTCTGCTTTACACCAGAGGCTTTCCTAGACTTGATCGGTGCCTTCAGCAGCATGTTCAATGCCAGAGCAGTGCT
CGATGGCGTTAGCCTCAGCCAACGAGAAACAATCGGCAAAAATATCGCCGTTCCATTCTTCTCCCTTCATGATAATGGCC
TACATCCTGCACATGTAGGTGCCTCTAGTTTCGATGGTGAAGGCACACCTACTCAAAAACTTTGCTTAATCAACGGTGGA
AGACTTGAGAGTTTCCTGCACTCGGAAGCTACCGCAAGGGCATTTGGTGTACCACCAACTGGCCATGCCGGACTGGGAGC
AAAGGTATCAGTGGGACCCGATTGGTTTGAAGTGAGCAAAACTGAAGGTCAAAACAGTGCAAATACTCATCTGCAACACA
GCAGGAGTAAAGAAACCTTCGTGTTAATCGAAGGGTTAAATGCTCTACATGCTGGGGTTAAAGCAAGTCAGGGTTCATTC
TCTTTGCCATTTAATGGTTGGTTGGTCATCAAAGGGGAAAGGGTGTCGATCGAAGCAGCGACAGTTGCTGGAGACATCCG
TACGCTGTTGAATAGCATTGTGAATATGGAAGCTGAACAGGTAATCACACCTGGTGGGGTATCTCCTCATGTGTGGGTCG
AAGGCTTATCAATTACTGGTGAAGCATGA

Upstream 100 bases:

>100_bases
AGCTGGCAGCCGGTTTCTGCGGGTCAATAAGCGGTAACATTTTTGTCACCGTAGGGCAGCCTCATATCAAAGTCGATTCA
ATCACCGTGGGAGGGCGTTG

Downstream 100 bases:

>100_bases
GGGTGCTGTTCTGGGGTACCCCCAGCTATGCAGTGCCAACTCTGGATGCCTTAAATGACTCAGGCTATGAAATTGTTGGC
GTGGTGAGTCAGCCTGATCG

Product: modulator of DNA gyrase

Products: NA

Alternate protein names: Modulator Of DNA Gyrase; PmbA Protein; TldD/PmbA Family Protein; Zn-Dependent Protease; Peptidase PmbA; PmbA-Related Protein; TldD/PmbA Family; Peptide Maturation; Pmba-Related Protein; Inactivated Zn-Dependent Peptidase PMBA Ortholog; Modulator Of DNA Gyrase Protein; PmbA/TldD Protein; Protein PmbA; Peptidase U; DNA Gyrase Modulator Peptidase U; Zn-Dependent Protease TLDE Protein; Protease PmbA; Protease; Modulator Of DNA Gyrase Family; Zinc Protease PmbA; Pmba/Tldd Protein; Regulatory Protease; Zn-Dependent Protease-Like Protein; Antibiotic/Peptide Maturation Related Protein

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MMSEIQAANAIELDTHSLRDKLSQLASRESIHQWDLGASCSTDSSVQIDRGEAKQMKGAQRSSITVRVWNNKGLVGITST
SDLSEKGIEKALIGARQASDFGNADDVPAFSTLAKSPLPKLERPLRPAQGIQRMLEVLKEAEADLLSRHPAIQSIPYNGL
GEATYERVYLNSDGALRQMKRSQASLYLFARAEESGRKPRSGGAIRLALGSHDLDIDGCIDEAAERTISHLDYQPIDTGC
YLVCFTPEAFLDLIGAFSSMFNARAVLDGVSLSQRETIGKNIAVPFFSLHDNGLHPAHVGASSFDGEGTPTQKLCLINGG
RLESFLHSEATARAFGVPPTGHAGLGAKVSVGPDWFEVSKTEGQNSANTHLQHSRSKETFVLIEGLNALHAGVKASQGSF
SLPFNGWLVIKGERVSIEAATVAGDIRTLLNSIVNMEAEQVITPGGVSPHVWVEGLSITGEA

Sequences:

>Translated_462_residues
MMSEIQAANAIELDTHSLRDKLSQLASRESIHQWDLGASCSTDSSVQIDRGEAKQMKGAQRSSITVRVWNNKGLVGITST
SDLSEKGIEKALIGARQASDFGNADDVPAFSTLAKSPLPKLERPLRPAQGIQRMLEVLKEAEADLLSRHPAIQSIPYNGL
GEATYERVYLNSDGALRQMKRSQASLYLFARAEESGRKPRSGGAIRLALGSHDLDIDGCIDEAAERTISHLDYQPIDTGC
YLVCFTPEAFLDLIGAFSSMFNARAVLDGVSLSQRETIGKNIAVPFFSLHDNGLHPAHVGASSFDGEGTPTQKLCLINGG
RLESFLHSEATARAFGVPPTGHAGLGAKVSVGPDWFEVSKTEGQNSANTHLQHSRSKETFVLIEGLNALHAGVKASQGSF
SLPFNGWLVIKGERVSIEAATVAGDIRTLLNSIVNMEAEQVITPGGVSPHVWVEGLSITGEA
>Mature_462_residues
MMSEIQAANAIELDTHSLRDKLSQLASRESIHQWDLGASCSTDSSVQIDRGEAKQMKGAQRSSITVRVWNNKGLVGITST
SDLSEKGIEKALIGARQASDFGNADDVPAFSTLAKSPLPKLERPLRPAQGIQRMLEVLKEAEADLLSRHPAIQSIPYNGL
GEATYERVYLNSDGALRQMKRSQASLYLFARAEESGRKPRSGGAIRLALGSHDLDIDGCIDEAAERTISHLDYQPIDTGC
YLVCFTPEAFLDLIGAFSSMFNARAVLDGVSLSQRETIGKNIAVPFFSLHDNGLHPAHVGASSFDGEGTPTQKLCLINGG
RLESFLHSEATARAFGVPPTGHAGLGAKVSVGPDWFEVSKTEGQNSANTHLQHSRSKETFVLIEGLNALHAGVKASQGSF
SLPFNGWLVIKGERVSIEAATVAGDIRTLLNSIVNMEAEQVITPGGVSPHVWVEGLSITGEA

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49553; Mature: 49553

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSEIQAANAIELDTHSLRDKLSQLASRESIHQWDLGASCSTDSSVQIDRGEAKQMKGAQ
CCCCCCCCCEEECCHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCEEECCCHHHHHCCCC
RSSITVRVWNNKGLVGITSTSDLSEKGIEKALIGARQASDFGNADDVPAFSTLAKSPLPK
CCEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHH
LERPLRPAQGIQRMLEVLKEAEADLLSRHPAIQSIPYNGLGEATYERVYLNSDGALRQMK
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEEEEECCCHHHHHHH
RSQASLYLFARAEESGRKPRSGGAIRLALGSHDLDIDGCIDEAAERTISHLDYQPIDTGC
HCCCEEEEEEECHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCE
YLVCFTPEAFLDLIGAFSSMFNARAVLDGVSLSQRETIGKNIAVPFFSLHDNGLHPAHVG
EEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEECEEEEECCCCCCHHHCC
ASSFDGEGTPTQKLCLINGGRLESFLHSEATARAFGVPPTGHAGLGAKVSVGPDWFEVSK
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEEEC
TEGQNSANTHLQHSRSKETFVLIEGLNALHAGVKASQGSFSLPFNGWLVIKGERVSIEAA
CCCCCCCHHHHHHCCCCCEEEEEECCHHHHCCCCCCCCCEECCCCCEEEEECCEEEEEHH
TVAGDIRTLLNSIVNMEAEQVITPGGVSPHVWVEGLSITGEA
HHHHHHHHHHHHHHCCCHHHEECCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure
MMSEIQAANAIELDTHSLRDKLSQLASRESIHQWDLGASCSTDSSVQIDRGEAKQMKGAQ
CCCCCCCCCEEECCHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCEEECCCHHHHHCCCC
RSSITVRVWNNKGLVGITSTSDLSEKGIEKALIGARQASDFGNADDVPAFSTLAKSPLPK
CCEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHH
LERPLRPAQGIQRMLEVLKEAEADLLSRHPAIQSIPYNGLGEATYERVYLNSDGALRQMK
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEEEEECCCHHHHHHH
RSQASLYLFARAEESGRKPRSGGAIRLALGSHDLDIDGCIDEAAERTISHLDYQPIDTGC
HCCCEEEEEEECHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCE
YLVCFTPEAFLDLIGAFSSMFNARAVLDGVSLSQRETIGKNIAVPFFSLHDNGLHPAHVG
EEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEECEEEEECCCCCCHHHCC
ASSFDGEGTPTQKLCLINGGRLESFLHSEATARAFGVPPTGHAGLGAKVSVGPDWFEVSK
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEEEC
TEGQNSANTHLQHSRSKETFVLIEGLNALHAGVKASQGSFSLPFNGWLVIKGERVSIEAA
CCCCCCCHHHHHHCCCCCEEEEEECCHHHHCCCCCCCCCEECCCCCEEEEECCEEEEEHH
TVAGDIRTLLNSIVNMEAEQVITPGGVSPHVWVEGLSITGEA
HHHHHHHHHHHHHHCCCHHHEECCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA