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The map label for this gene is mdtE [H]

Identifier: 30065157

GI number: 30065157

Start: 4072203

End: 4072499

Strand: Direct

Name: mdtE [H]

Synonym: S4169

Alternate gene names: 30065157

Gene position: 4072203-4072499 (Clockwise)

Preceding gene: 30065154

Following gene: 30065164

Centisome position: 88.54

GC content: 50.84

Gene sequence:

>297_bases
ATGATTTTCAAAAATATCTTGAATAATTTTGCGCGCTTTATATTACTGGTGCCGCAGGAAGGCGTCACCCACAACGCCCA
GGGTAAAGCAACGGCGCTCATTCTGGATAAAGACGATGTCGTGCAGCTACGCGAAATTGAAGCCAGCAAAGCCATCGGCG
ACCAGTGGGTTGTCACCTCTGGCTTGCAGGCTGGCGATCGGGTGATCGTTTCCGGTTTGCAACGCATTCGTCCGGGTATC
AAAGCACGAGCAATTTCCTCCAGCCAGGAAAACGCCAGCACCGAATCGAAACAATAA

Upstream 100 bases:

>100_bases
ACTGGAAACACGAAACTTAATACTCCCATTCCTGATTGCTTAATAATCAAGCATTTTTATCTTGAATGTTTTTGCTATCA
CACGCGATAGCCTATCTTGA

Downstream 100 bases:

>100_bases
CGTTGCAGGCTTAAGGGGACTTTCATGGCTAACTATTTTATTGATCGCCCGGTTTTTGCCTGGGTACTTGCCATTATTAT
GATGCTTGCAGGTGGTCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MIFKNILNNFARFILLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGI
KARAISSSQENASTESKQ

Sequences:

>Translated_98_residues
MIFKNILNNFARFILLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGI
KARAISSSQENASTESKQ
>Mature_98_residues
MIFKNILNNFARFILLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGI
KARAISSSQENASTESKQ

Specific function: Part of a multidrug resistance efflux system that confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=85, Percent_Identity=98.8235294117647, Blast_Score=171, Evalue=1e-44,
Organism=Escherichia coli, GI1786668, Length=77, Percent_Identity=53.2467532467532, Blast_Score=94, Evalue=2e-21,
Organism=Escherichia coli, GI1789665, Length=83, Percent_Identity=45.7831325301205, Blast_Score=79, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 10672; Mature: 10672

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKNILNNFARFILLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTS
CCHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEC
GLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ
CCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MIFKNILNNFARFILLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTS
CCHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEC
GLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ
CCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]