| Definition | Shigella flexneri 2a str. 2457T, complete genome. |
|---|---|
| Accession | NC_004741 |
| Length | 4,599,354 |
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The map label for this gene is bglF
Identifier: 30065037
GI number: 30065037
Start: 3931105
End: 3932982
Strand: Reverse
Name: bglF
Synonym: S4039
Alternate gene names: 30065037
Gene position: 3932982-3931105 (Counterclockwise)
Preceding gene: 30065038
Following gene: 30065036
Centisome position: 85.51
GC content: 51.38
Gene sequence:
>1878_bases ATGACGGAGTTAGCCAGAAAAATAGTCGCAGGAGTCGGGGGCGCAGATAACATTGTGAGTCTGATGCATTGCGCAACGCG ATTACGTTTTAAGTTAAAGGATGAAAGCAAAGCGCAAGCTGAGGTACTGAAAAAGACCCCCGGTATTATTATGGTGGTGG AAAGCGGTGGTCAGTTTCAGGTGGTCATAGGTAACCATGTGGCCGATGTCTTCCTGGCGGTTAACAGCGTGGCAGGCCTT GGCGAAAAAGCGCAACAGGCACCGGAAAATGATGAGAAAGGTAATCTGCTAAACCGCTTTGTTTATGTTATTTCAGGTAT TTTTACGCCTCTGATCGGTCTGATGGCGGCAACCGGGATCCTGAAAGGTATGCTGGCTCTGGCGCTCACTTTTCAGTGGA CGACCGAACAAAGTGGTACTTATTTAATTTTATTCAGCGCCAGTGATGCCTTGTTTGGGTTCTTCCCGATAATCCTGGGA TACACCGCGGGCAAACGCTTCGGCGGTAATCCATTTACTGCCATGGTGATTGGTGGAGCGTTAGTGCATCCATTAATTCT GACTGCCTTCGAGAACGGGCAAAAAGCGGATGCGCCGGGGCTGGATTTCCTGGGTATTCCGGTCACATTGTTGAATTACT CGTCATCGGTTATTCCCATTATTTTTTCTGCCTGGTTGTGCAGCATTCTGGAACGCCGACTTAATGCGTGGTTACCGTCG GCAATCAAAAATTTCTTCACACCATTGCTATGTCTGATGGTTATCACACCCGTCACCTTTCTGCTGGTGGGGCAGCTATC AACCTGGATAAGCGAAATGATTGCCGCCGGTTATCTCTGGCTTTATCAGGCGGTTCCTGCATTTGCGGGCGCGGTAATGG GCGGCTTCTGGCAAATCTTCGTCATGTTCGGACTGCACAGGGGCCTGGTGCCGCTGTGTATCAATAACTTCACCGTGCTG GGCTACGACACCATGATCCCGCTGTTAATGCCCGCCATTATGGCGCAGGTCGGGGCGGCGCTCGGCGTCTTCCTCTGCGA ACGCGATGCGCAGAAAAAAGTGGTGGCGGGATCAGCGGCGTTGACGGGTCTGTTTGGTATCACCGAACCAGCGGTATATG GCGTCAACCTGCCGCGTAAGTACCCCTTTGTTATCGCCTGTATCAGTGGAGCATTGGGGGCCACCATCATTGGCTACGCG CAAACGAAAGTTTACTCCTTTGGTTTGCCAAGTATTTTCACCTTCATGCAGACCATCCCGTCAACGGGGATTGATTTCAC CGTCTGGGCCAGCGTTATTGGCGGTGTCATTGCCATAGGTTGCGCATTTGTTGGTACGTTGATGCTTCATTTCATCACCA GTAAACGTCAGCCAGCGCAGGGTGCCCCGCAAGAGAAAACACCAGAGGTTATTACACCACCTGAGCAGGGCGGTATCTGT TCACCGATGACGGGAGAGATTGTGCCGCTCATTCACGTCGCTGATACCACGTTTGCCAGTGGCCTGTTGGGTAAAGGTAT CGCCATTCTGCCCTCGGTTGGTGAAGTGCGTTCTCCGGTTGCGGGTCGAATTGCTTCGTTGTTCGCCACATTACACGCCA TTGGCATTGAGTCAGATGATGGTGTGGAGATCCTGATTCATGTCGGTATCGACACCGTAAAACTGGACGGCAAATTCTTT TCCGCTCACGTCAACGTGGGTGACAAGGTCAATACAGGCGATCGGCTGATTTCTTTTGATATCCCTGCTATTCGCGAGGC CGGATTTGATCTGACGACGCCGGTATTAATCAGTAATAGCGATGATTTTACAGACGTATTACCCCACGGCACGGCGCAGA TAAGCGCAGGTGAACCGCTGTTATCCATCATTCGCTAA
Upstream 100 bases:
>100_bases CTAAGCGGGCAAAACCTGAAAAAAATTGCTTGATTCACGTCAGGCCGTTTTTTTCAGGTTTTTTTTTGGAGTTTTGCCGC AAAGCGGTAGAGGGCAAGTT
Downstream 100 bases:
>100_bases CGATAAAAGGAGTTAATTATGAAAGCATTTCCAGAAACATTTCTTTGGGGTGGCGCAACAGCTGCCAATCAGGTGGAAGG TGCCTGGCTGGAAGATGGCA
Product: PTS system beta-glucoside-specific transporter subunits IIABC
Products: NA
Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]
Number of amino acids: Translated: 625; Mature: 624
Protein sequence:
>625_residues MTELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGL GEKAQQAPENDEKGNLLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFGFFPIILG YTAGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADAPGLDFLGIPVTLLNYSSSVIPIIFSAWLCSILERRLNAWLPS AIKNFFTPLLCLMVITPVTFLLVGQLSTWISEMIAAGYLWLYQAVPAFAGAVMGGFWQIFVMFGLHRGLVPLCINNFTVL GYDTMIPLLMPAIMAQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGVNLPRKYPFVIACISGALGATIIGYA QTKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTLMLHFITSKRQPAQGAPQEKTPEVITPPEQGGIC SPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFF SAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSIIR
Sequences:
>Translated_625_residues MTELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGL GEKAQQAPENDEKGNLLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFGFFPIILG YTAGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADAPGLDFLGIPVTLLNYSSSVIPIIFSAWLCSILERRLNAWLPS AIKNFFTPLLCLMVITPVTFLLVGQLSTWISEMIAAGYLWLYQAVPAFAGAVMGGFWQIFVMFGLHRGLVPLCINNFTVL GYDTMIPLLMPAIMAQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGVNLPRKYPFVIACISGALGATIIGYA QTKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTLMLHFITSKRQPAQGAPQEKTPEVITPPEQGGIC SPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFF SAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSIIR >Mature_624_residues TELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLG EKAQQAPENDEKGNLLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFGFFPIILGY TAGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADAPGLDFLGIPVTLLNYSSSVIPIIFSAWLCSILERRLNAWLPSA IKNFFTPLLCLMVITPVTFLLVGQLSTWISEMIAAGYLWLYQAVPAFAGAVMGGFWQIFVMFGLHRGLVPLCINNFTVLG YDTMIPLLMPAIMAQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGVNLPRKYPFVIACISGALGATIIGYAQ TKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTLMLHFITSKRQPAQGAPQEKTPEVITPPEQGGICS PMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFS AHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSIIR
Specific function: Acts as both a kinase and a phosphatase on BglG [H]
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1790159, Length=625, Percent_Identity=98.4, Blast_Score=1233, Evalue=0.0, Organism=Escherichia coli, GI48994906, Length=464, Percent_Identity=32.1120689655172, Blast_Score=201, Evalue=8e-53, Organism=Escherichia coli, GI1788769, Length=435, Percent_Identity=29.8850574712644, Blast_Score=151, Evalue=1e-37, Organism=Escherichia coli, GI2367362, Length=404, Percent_Identity=25.2475247524752, Blast_Score=144, Evalue=2e-35, Organism=Escherichia coli, GI1788757, Length=146, Percent_Identity=41.0958904109589, Blast_Score=112, Evalue=6e-26, Organism=Escherichia coli, GI1786894, Length=162, Percent_Identity=36.4197530864198, Blast_Score=107, Evalue=2e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011055 - InterPro: IPR018113 - InterPro: IPR004719 - InterPro: IPR001127 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR011297 [H]
Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 66314; Mature: 66182
Theoretical pI: Translated: 6.35; Mature: 6.35
Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVESGGQFQ CHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCEEEEEECCCEEE VVIGNHVADVFLAVNSVAGLGEKAQQAPENDEKGNLLNRFVYVISGIFTPLIGLMAATGI EEECCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH LKGMLALALTFQWTTEQSGTYLILFSASDALFGFFPIILGYTAGKRFGGNPFTAMVIGGA HHHHHHHHHEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH LVHPLILTAFENGQKADAPGLDFLGIPVTLLNYSSSVIPIIFSAWLCSILERRLNAWLPS HHHHHHHHHHCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCHH AIKNFFTPLLCLMVITPVTFLLVGQLSTWISEMIAAGYLWLYQAVPAFAGAVMGGFWQIF HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VMFGLHRGLVPLCINNFTVLGYDTMIPLLMPAIMAQVGAALGVFLCERDAQKKVVAGSAA HHHHHHHCCHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHH LTGLFGITEPAVYGVNLPRKYPFVIACISGALGATIIGYAQTKVYSFGLPSIFTFMQTIP HHHHHCCCCCCEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHC STGIDFTVWASVIGGVIAIGCAFVGTLMLHFITSKRQPAQGAPQEKTPEVITPPEQGGIC CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC SPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGIESDD CCCCCCCEEEEEECCHHHHHHHHCCCEEECCCCHHHHCHHHHHHHHHHHHHHHHCCCCCC GVEILIHVGIDTVKLDGKFFSAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNS CCEEEEEECCEEEEECCEEEEEEECCCCCCCCCCEEEEECCCHHHHCCCCCCCCEEEECC DDFTDVLPHGTAQISAGEPLLSIIR CCHHHHCCCCCEEECCCCHHHHHCC >Mature Secondary Structure TELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVESGGQFQ HHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCEEEEEECCCEEE VVIGNHVADVFLAVNSVAGLGEKAQQAPENDEKGNLLNRFVYVISGIFTPLIGLMAATGI EEECCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH LKGMLALALTFQWTTEQSGTYLILFSASDALFGFFPIILGYTAGKRFGGNPFTAMVIGGA HHHHHHHHHEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH LVHPLILTAFENGQKADAPGLDFLGIPVTLLNYSSSVIPIIFSAWLCSILERRLNAWLPS HHHHHHHHHHCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCHH AIKNFFTPLLCLMVITPVTFLLVGQLSTWISEMIAAGYLWLYQAVPAFAGAVMGGFWQIF HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VMFGLHRGLVPLCINNFTVLGYDTMIPLLMPAIMAQVGAALGVFLCERDAQKKVVAGSAA HHHHHHHCCHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHH LTGLFGITEPAVYGVNLPRKYPFVIACISGALGATIIGYAQTKVYSFGLPSIFTFMQTIP HHHHHCCCCCCEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHC STGIDFTVWASVIGGVIAIGCAFVGTLMLHFITSKRQPAQGAPQEKTPEVITPPEQGGIC CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC SPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGIESDD CCCCCCCEEEEEECCHHHHHHHHCCCEEECCCCHHHHCHHHHHHHHHHHHHHHHCCCCCC GVEILIHVGIDTVKLDGKFFSAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNS CCEEEEEECCEEEEECCEEEEEEECCCCCCCCCCEEEEECCCHHHHCCCCCCCCEEEECC DDFTDVLPHGTAQISAGEPLLSIIR CCHHHHCCCCCEEECCCCHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3309161; 3034860; 7686882; 9278503 [H]