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The map label for this gene is basS

Identifier: 30064681

GI number: 30064681

Start: 3495795

End: 3496895

Strand: Reverse

Name: basS

Synonym: S3619

Alternate gene names: 30064681

Gene position: 3496895-3495795 (Counterclockwise)

Preceding gene: 30064682

Following gene: 30064677

Centisome position: 76.03

GC content: 54.31

Gene sequence:

>1101_bases
TTGAATCTGATGCGTTTTCTGCGCCGACCTATATCGCTGCGCCAACGGCTGATATTGACCATCGGGGCCATTTTGTTGGT
GTTTGAGCTGATCAGCGTCTTCTGGCTATGGCATGAAAGTACCGAGCAGATTCAGCTGTTTGAGCAGGCGCTACGCGACA
ATCGCAACAACGATCGCCACATCATGCGTGAGATCCGCGAGGCGGTCGCCAGCCTGATTGTCCCCGGCGTCTTTATGGTC
AGCCTGACGCTATTTATCTGCTATCAGGCGGTACGCCGCATCACCCGCCCGCTGGCGGAGCTGCAAAAAGAGCTGGAAGC
GCGCACCGCCGACAACTTAACGCCCATTGCCATTCACAGCGCCACCCTCGAAATCGAAGCGGTGGTTTCGGCGTTGAACG
ATCTGGTCAGTCGCCTGACCAGCACGCTGGATAACGAAAGGTTGTTTACCGCTGACGTCGCGCACGAACTGCGAACGCCA
CTGGCGGGGGTGCGTTTGCATCTGGAACTGCTGGCGAAAACGCATCACATTGATGTAGCACCGTTAGTGGCACGGCTTGA
TCAGATGATGGAGAGCGTCTCCCAGCTGCTGCAACTGGCGCGTGCCGGACAGTCATTTTCTTCCGGTAATTATCAACATG
TAAAACTGCTGGAAGATGTCATTCTCCCCTCGTATGACGAACTCAGTACCATGCTCGACCAGCGACAGCAAACCCTGCTA
TTGCCAGAGAGCGCCGCCGACATCACCGTTCAGGGTGATGCAACCCTGCTGCGGATGTTATTGCGAAACCTGGTAGAAAA
CGCCCATCGTTACAGCCCGCAAGGCAGCAACATTATGATTAAGCTGCAAGAAGATGGCGGAGCGGTCATGGCAGTTGAAG
ATGAAGGACCAGGTATTGATGAGAGTAAATGCGGGGAGTTGAGTAAAGCGTTTGTACGTATGGACAGCCGTTATGGCGGG
ATTGGTCTGGGGTTAAGTATTGTCAGCCGCATTACACAGTTGCATCACGGGCAGTTTTTCCTGCAAAACCGGCAAGAGAC
TTCCGGCACGCGGGCCTGGGTACGGCTGAAGAAAGATCAGAACGTGGCAAACCAGATATAA

Upstream 100 bases:

>100_bases
GGAAGTGCATATCCACAATCTGCGCGACAAAGTGGGCAAAGCCCGTATCCGCACCGTGCGCGGCTTTGGCTATATGCTGG
TCGCGAATGAGGAAAACTAA

Downstream 100 bases:

>100_bases
AGAAAGCTGCTGACCACCAGCACGCTGAACACGGTAGTTAAACTTTCATAAACACGGTTTTTCATTGCACTCTCCTCCGT
TAACCTGGAGGAGAGTATGC

Product: sensor protein BasS/PmrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMV
SLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLL
LPESAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGG
IGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQNVANQI

Sequences:

>Translated_366_residues
MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMV
SLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLL
LPESAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGG
IGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQNVANQI
>Mature_366_residues
MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMV
SLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLL
LPESAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGG
IGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQNVANQI

Specific function: Member of the two-component regulatory system BasS/BasR Autophosphorylates and activates BasR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=363, Percent_Identity=99.1735537190083, Blast_Score=729, Evalue=0.0,
Organism=Escherichia coli, GI1789403, Length=276, Percent_Identity=32.2463768115942, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789808, Length=270, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786783, Length=303, Percent_Identity=27.7227722772277, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=29.3436293436293, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786600, Length=199, Percent_Identity=31.1557788944724, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=26.4069264069264, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=292, Percent_Identity=28.4246575342466, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081816, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=214, Percent_Identity=30.8411214953271, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787374, Length=254, Percent_Identity=27.1653543307087, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41300; Mature: 41300

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRH
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHH
IMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
ATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAGVRLHLELLAKTHHIDVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
PLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEE
LPESAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAVMAVEDEGPGID
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCC
ESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEEECCC
NVANQI
CHHCCC
>Mature Secondary Structure
MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRH
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHH
IMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
ATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAGVRLHLELLAKTHHIDVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
PLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEE
LPESAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAVMAVEDEGPGID
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCC
ESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEEECCC
NVANQI
CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]