Click here to switch to the map view.

The map label for this gene is actP

Identifier: 30064657

GI number: 30064657

Start: 3466028

End: 3467677

Strand: Reverse

Name: actP

Synonym: S3594

Alternate gene names: 30064657

Gene position: 3467677-3466028 (Counterclockwise)

Preceding gene: 30064658

Following gene: 30064656

Centisome position: 75.39

GC content: 55.33

Gene sequence:

>1650_bases
ATGAAAAGAGTTCTGACGGCGCTTGCCGCCACACTCCCTTTCGCAGCTAACGCCGCGGATGCTATTAGCGGGGCCGTAGA
GCGCCAGCCAACGAACTGGCAGGCGATTATTATGTTCCTGATTTTCGTCGTGTTTACGCTCGGCATTACCTACTGGGCAT
CAAAACGCGTACGTTCTCGTAGCGACTACTACACCGCAGGCGGCAATATCACTGGCTTCCAGAACGGGCTGGCGATTGCC
GGGGACTATATGTCCGCCGCCTCATTCTTGGGGATCTCCGCGCTGGTGTTTACCTCCGGCTATGACGGGCTGATCTACTC
GTTGGGCTTCCTGGTGGGCTGGCCAATCATTCTGTTTCTGATTGCCGAACGTCTGCGTAACCTGGGACGCTACACCTCTG
CCGATGTGGCCTCTTATCGTCTGAAACAAGGGCCGATTCGTATTCTTTCGGCCTGTGGTTCTCTGGTAGTGGTGGCGCTT
TACCTTATCGCTCAGATGGTAGGCGCAGGTAAACTGATCGAGCTGCTGTTTGGCCTTAACTATCACATTGCGGTGGTGCT
GGTCGGCGTGCTGATGATGATGTACGTCCTGTTCGGCGGCATGCTGGCGACCACCTGGGTACAAATTATCAAAGCTGTGC
TGTTGCTGTTCGGTGCCAGCTTTATGGCCTTTATGGTGATGAAACACGTCGGCTTTAGCTTCAACAATCTGTTCAGCGAA
GCGATGGCGGTACACCCGAAAGGTGTCGACATCATGAAACCGGGCGGACTGGTGAAAGATCCGATCTCCGCGCTCTCTCT
GGGGCTGGGACTGATGTTTGGTACGGCGGGCTTGCCGCACATTCTGATGCGCTTCTTTACAGTCAGCGATGCCCGCGAAG
CACGTAAGAGCGTGTTCTACGCCACCGGATTTATGGGCTACTTCTATATTCTGACCTTTATTATCGGCTTCGGCGCGATC
ATGCTTGTTGGTGCGAATCCGGAATATAAAGACGCGGCGGGCCATCTGATTGGTGGTAACAACATGGCGGCCGTTCACCT
GGCGAATGCAGTGGGCGGCAACCTATTCCTCGGTTTTATTTCAGCGGTTGCTTTCGCCACTATCCTCGCGGTGGTTGCGG
ATCTGACGCTGGCGGGCGCATCGGCGGTTTCGCATGACTTGTACGCTAACGTCTTCAAAAAAGGCGCGACCGAACGTGAA
GAGCTGCGGGTATCAAAAATCACCGTACTGATCCTCGGCGTGATTGCGATTATCCTCGGCGTGCTGTTTGAGAATCAGAA
CATCGCCTTTATGGTAGGCCTTGCGTTTGCCATCGCGGCGAGCTGTAACTTCCCGATCATTCTGCTTTCCATGTACTGGT
CGAAACTGACTACCCGTGGCGCGATGCTGGGCGGCTGGCTGGGGCTGATTACCGCAGTGGTGCTGATGATCCTCGGCCCG
ACTATTTGGGTACAGATCCTCGGTCACGAAAAAGCCATCTTCCCGTATGAATACCCGGCGCTGTTCTCTATCAGCGTGGC
ATTCCTCGGCATCTGGTTCTTCTCGGCAACCGATAACTCAGCGGAAGGGGCGCGCGAGCGTGAACTGTTCCGCGCGCAGT
TTATCCGCTCCCAGACCGGCTTTGGCGTTGAGCAAGGCCGCGCACATTAA

Upstream 100 bases:

>100_bases
TGATTGTGATCTCCTTTGTTCTCACCGGTATCTACATCTGGCGGGCGAACGGCGAATTCGACCGTCTTAATAATGAAGTC
CTGCATGAGGTACAAGCATC

Downstream 100 bases:

>100_bases
TCTCTCCCCTTCCCCGGTCGCCTGACCGGGGAATACGCTTCCTCTCCAACATGCATCACCTTTTCCCATAATATTAAACA
AATAAACTCATTAAAAAATG

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTSADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVADLTLAGASAVSHDLYANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH

Sequences:

>Translated_549_residues
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTSADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVADLTLAGASAVSHDLYANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
>Mature_549_residues
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTSADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVADLTLAGASAVSHDLYANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=469, Percent_Identity=26.4392324093817, Blast_Score=126, Evalue=5e-29,
Organism=Escherichia coli, GI1790503, Length=549, Percent_Identity=99.2714025500911, Blast_Score=1084, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=460, Percent_Identity=26.7391304347826, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59164; Mature: 59164

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCC
>Mature Secondary Structure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CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA