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The map label for this gene is yhaR

Identifier: 30064456

GI number: 30064456

Start: 3242345

End: 3242734

Strand: Reverse

Name: yhaR

Synonym: S3365

Alternate gene names: 30064456

Gene position: 3242734-3242345 (Counterclockwise)

Preceding gene: 30064457

Following gene: 30064455

Centisome position: 70.5

GC content: 52.56

Gene sequence:

>390_bases
ATGAAAAAGATTATCGAAACGCAACGTGCCCCAGGCGCAATCGGCCCTTATGTTCAGGGCGTTGATTTAGGCAGCATGGT
CTTCACCTCCGGGCAAATTCCGGTTTGCCCGCAGACCGGTGAGATCCCGGCTGATGTGCAAGATCAGGCGCGTTTAAGCC
TCGAAAACGTCAAAGCGATCGTGGTTGCTGCCGGGCTGAGCGTGGGCGATATCATCAAGATGACCGTGTTCATCACCGAT
CTGAATGATTTTGCCACCATCAATGAAGTCTATAAGCAGTTCTTCGATGAGCATCAGGCGACCTACCCGACCCGGAGCTG
TGTGCAGGTTGCGCGTTTGCCGAAAGATGTGAAGCTGGAAATTGAAGCTATCGCAGTACGTAGTGCGTAA

Upstream 100 bases:

>100_bases
GTCTCTGGCTACGCCGTGCGCTTCAACGCACTGACCCGTGAACAGCAACAGGATGTTATTTCACGTACTTTTACCCAGGC
GCTCTGACGCCGGAGGATGT

Downstream 100 bases:

>100_bases
AGCCTCGTGAGCGGGACGGTCGCAAGGTCGTTCCGCTCCACTTCACTGAACGGCAATCCGAGGGTGTGGATATGATTAGT
GCATTCGATATTTTCAAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITD
LNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA

Sequences:

>Translated_129_residues
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITD
LNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>Mature_129_residues
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITD
LNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0251

COG function: function code J; Putative translation initiation inhibitor, yjgF family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RutC family

Homologues:

Organism=Homo sapiens, GI5032215, Length=128, Percent_Identity=41.40625, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87082213, Length=129, Percent_Identity=100, Blast_Score=263, Evalue=2e-72,
Organism=Escherichia coli, GI87082396, Length=127, Percent_Identity=74.0157480314961, Blast_Score=200, Evalue=3e-53,
Organism=Escherichia coli, GI1787245, Length=125, Percent_Identity=29.6, Blast_Score=63, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71982075, Length=125, Percent_Identity=42.4, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25148896, Length=125, Percent_Identity=42.4, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71982068, Length=125, Percent_Identity=42.4, Blast_Score=112, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6322138, Length=122, Percent_Identity=38.5245901639344, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320899, Length=103, Percent_Identity=38.8349514563107, Blast_Score=89, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921376, Length=127, Percent_Identity=41.7322834645669, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TDCF_ECOL6 (P0AGL3)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_755738.1
- ProteinModelPortal:   P0AGL3
- SMR:   P0AGL3
- EnsemblBacteria:   EBESCT00000041583
- GeneID:   1040096
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c3871
- GeneTree:   EBGT00050000009258
- HOGENOM:   HBG695954
- OMA:   EGIVEQT
- ProtClustDB:   PRK11401
- InterPro:   IPR013813
- InterPro:   IPR006175
- InterPro:   IPR006056
- InterPro:   IPR019897
- Gene3D:   G3DSA:3.30.1330.40
- PANTHER:   PTHR11803
- TIGRFAMs:   TIGR00004

Pfam domain/function: PF01042 Ribonuc_L-PSP; SSF55298 YjgF/chorismate_mutase-like

EC number: NA

Molecular weight: Translated: 14007; Mature: 14007

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01094 UPF0076

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAI
CCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHEEE
VVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLE
EEECCCCHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEE
IEAIAVRSA
EEEEEEECC
>Mature Secondary Structure
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAI
CCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHEEE
VVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLE
EEECCCCHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEE
IEAIAVRSA
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157