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The map label for this gene is tdcG [H]

Identifier: 30064455

GI number: 30064455

Start: 3240909

End: 3242273

Strand: Reverse

Name: tdcG [H]

Synonym: S3363

Alternate gene names: 30064455

Gene position: 3242273-3240909 (Counterclockwise)

Preceding gene: 30064456

Following gene: 30064454

Centisome position: 70.49

GC content: 53.41

Gene sequence:

>1365_bases
ATGATTAGTGCATTCGATATTTTCAAAATTGGGATTGGTCCCTCCAGTTCGCATACCGTGGGGCCAATGAATGCCGGAAA
AAGTTTTATTGATCGGCTGGAAAGTAGCGGCTTATTAACCGCGACGAGCCATATTGTGGTCGATCTGTACGGGTCGTTGT
CACTGACGGGCAAAGGCCATGCCACGGATGTCGCCATTATCATGGGACTGGCAGGAAACAGTCCGCAGGATGTTGTCATT
GATGAGATCCCTGCATTTATAGAGTTAGTAACGCGCAGCGGGCGGCTGCCAGTGGCATCTGGTGCGCATATTGTTGATTT
TCCTGTAGCAAAGAACATTATCTTCCATCCCGAAATGTTGCCTCGCCATGAGAACGGAATGCGGATCACTGCCTGGAAGG
GACAGGAAGCGCTATTAAGTAAAACCTATTACTCTGTCGGCGGCGGGTTTATTGTCGAAGAAGAACACTTCGGCCTGTCG
CACGATGTCGAAACGTCCGTACCTTACGATTTCCACTCAGCAGGTGAACTGCTGAAAATGTGTGATTACAACGGCCTGTC
TATATCTGGCCTGATGATGCACAACGAGCTGGCGCTGCGCAGCAAAGCGGAAATTGACGCAGGGTTTGCCCGTATCTGGC
AAGTGATGCATGACGGTATTGAACGCGGGATGAACACTGAAGGCGTGCTGCCTGGTCCGCTCAATGTGCCGTGTCGTGCC
GTAGCGCTGCGTCGTCAGCTGGTTTCTAGCGATAACATCTCTAACGATCCGATGAATGTCATCGACTGGATCAACATGTA
CGCGCTGGCGGTTAGTGAAGAAAACGCAGCTGGCGGGCGCGTGGTAACGGCACCGACTAACGGTGCGTGCGGCATTATTC
CGGCAGTGCTGGCTTATTACGATAAGTTCCGTCGTCCGGTAAACGAGCGGTCAATTGCCCGCTATTTTCTGGCAGCGGGG
GCTATTGGCGCGCTGTATAAAATGAACGCCTCCATCTCTGGCGCGGAGGTCGGCTGTCAGGGGGAGATTGGCGTGGCCTG
TTCAATGGCAGCGGCAGGGTTAACTGAACTACTGGGCGGCAGTCCGGCGCAGGTATGCAATGCGGCGGAAATCGCGATGG
AGCATAACCTTGGGCTGACCTGCGATCCGGTTGCCGGACAGGTACAAATCCCGTGCATTGAACGTAATGCCATTAATGCC
GTGAAAGCAGTAAACGCCGCGCGGATGGCGATGCGCCGCACCTCGGCACCGCGTGTTTCACTCGATAAAGTGATCGAGAC
GATGTATGAAACCGGCAAAGATATGAACGATAAATACCGCGAAACATCACGCGGAGGACTGGCCATTAAAGTGGTCTGCG
GCTGA

Upstream 100 bases:

>100_bases
TTGAAGCTATCGCAGTACGTAGTGCGTAAAGCCTCGTGAGCGGGACGGTCGCAAGGTCGTTCCGCTCCACTTCACTGAAC
GGCAATCCGAGGGTGTGGAT

Downstream 100 bases:

>100_bases
CATTGCTGTCAGCTTTCATCCTTGGGTGCACAAATGTGCACCTTTTTTTTGTGATCTGCCGCAAATAGAGAATGAATATT
CTCTTGTGATTAATTTAGTA

Product: putative L-serine deaminase

Products: NA

Alternate protein names: SDH; L-serine deaminase [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVI
DEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS
HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPCRA
VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAG
AIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA
VKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG

Sequences:

>Translated_454_residues
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVI
DEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS
HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPCRA
VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAG
AIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA
VKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>Mature_454_residues
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVI
DEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS
HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPCRA
VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAG
AIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA
VKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=454, Percent_Identity=99.5594713656388, Blast_Score=927, Evalue=0.0,
Organism=Escherichia coli, GI1788116, Length=453, Percent_Identity=73.7306843267108, Blast_Score=677, Evalue=0.0,
Organism=Escherichia coli, GI1789161, Length=452, Percent_Identity=72.5663716814159, Blast_Score=668, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48411; Mature: 48411

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGH
CCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCEEEEEEECCEEECCCCC
ATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEML
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEECCCCC
PRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKM
CCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
CDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPCRA
HCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYY
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHH
DKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGG
HHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVS
CHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
LDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGH
CCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEECCEEEEEEECCEEECCCCC
ATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEML
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEECCCCC
PRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKM
CCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
CDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPCRA
HCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYY
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHH
DKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGG
HHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVS
CHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
LDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9484901 [H]