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The map label for this gene is uppP

Identifier: 30064405

GI number: 30064405

Start: 3181079

End: 3181900

Strand: Reverse

Name: uppP

Synonym: S3303

Alternate gene names: 30064405

Gene position: 3181900-3181079 (Counterclockwise)

Preceding gene: 30064406

Following gene: 30064402

Centisome position: 69.18

GC content: 52.55

Gene sequence:

>822_bases
ATGAGCGATATGCACTCGCTGCTGATAGCGGCAATATTGGGTGTGGTCGAAGGATTGACAGAATTTCTGCCGGTATCCAG
CACGGGCCATATGATTATTGTCGGTCACTTGTTGGGGTTTGAGGGCGACACGGCGAAAACCTTTGAAGTTGTGATCCAGT
TAGGATCAATTCTGGCGGTAGTAGTGATGTTCTGGCGGCGTCTGTTTGGCCTGATTGGCATCCACTTTGGCCGCCCGTTG
CAGCACGAAGGTGAAAGCAAAGGTCGTTTAACGCTGATCCACATTTTGCTGGGGATGATTCCGGCGGTGGTACTGGGGCT
ATTATTCCACGACACGATTAAGTCATTGTTTAACCCGATAAATGTGATGTATGCGCTGGTCGTTGGCGGTTTGTTGCTGA
TTGCCGCCGAATGCCTGAAGCCGAAAGAGCCGCGTGCGCCGGGTCTTGATGATATGACCTATCGTCAGGCGTTTATGATT
GGCTGTTTCCAGTGTCTGGCGCTGTGGCCGGGTTTCTCCCGTTCCGGGGCGACCATTTCAGGTGGGATGCTGATGGGCGT
GAGCCGTTACGCTGCTTCCGAGTTCTCGTTCCTGCTGGCGGTACCGATGATGATGGGCGCAACGGCGCTCGATCTCTACA
AAAGCTGGGGCTTCCTGACAACCGGCGATATCCCGATGTTTGCCGTTGGGTTTATCACCGCTTTTGTGGTGGCGCTGATA
GCGATTAAAACCTTCCTGCAATTGATTAAGCGCATTTCGTTTATCCCGTTCGCCATTTATCGCTTTATTGTGGCGGCTGC
GGTGTATGTCGTGTTCTTTTGA

Upstream 100 bases:

>100_bases
AAATAATTAATTTTACAGCTGTTAAACCAAACGGTTATAACCTGGTCATACTGCAGTAGTTCGGACAAGCGGTACATTTT
AATAATTTAGGGGTTTATTG

Downstream 100 bases:

>100_bases
TTGAGAAAAGGTTCGGGAGCAGGCCGGGTTTTCTCCCTCGCTCTGTAGGGAGAGGGCCGGGGTGGGGGTGATTGTTCGCA
CCGGTGCTGGTCTGTTCCCC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPL
QHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALI
AIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF

Sequences:

>Translated_273_residues
MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPL
QHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALI
AIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
>Mature_272_residues
SDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQ
HEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIG
CFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIA
IKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=273, Percent_Identity=99.6336996336996, Blast_Score=543, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_ECO24 (A7ZRT8)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001464517.1
- STRING:   A7ZRT8
- EnsemblBacteria:   EBESCT00000019197
- GeneID:   5589698
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_3520
- eggNOG:   COG1968
- GeneTree:   EBGT00050000011219
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- ProtClustDB:   PRK00281
- BioCyc:   ECOL331111:ECE24377A_3520-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29773; Mature: 29642

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14fe9c0c)-; HASH(0x14d93e04)-; HASH(0x14dfcdd8)-; HASH(0x14d93fe4)-; HASH(0x14e3b140)-; HASH(0x14ea96cc)-; HASH(0x14e2b578)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHH
VVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
GGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
AIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA