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The map label for this gene is glcC

Identifier: 30064328

GI number: 30064328

Start: 3104940

End: 3105710

Strand: Direct

Name: glcC

Synonym: S3220

Alternate gene names: 30064328

Gene position: 3104940-3105710 (Clockwise)

Preceding gene: 30064320

Following gene: 30064329

Centisome position: 67.51

GC content: 54.99

Gene sequence:

>771_bases
ATGAAAGATGAACGTCGCCCTATTTGCGAAGTGGTTGCAGAGAGTATCGAACGGTTAATTATCGACGGCGTACTGAAGGT
CGGTCAGCCGCTTCCCTCGGAACGTCGACTGTGTGAAAAGCTCGGCTTCTCACGCTCCGCACTGCGTGAAGGGCTGACCG
TGCTGCGCGGGCGCGGGATTATTGAAACGGCGCAGGGTCGCGATTCTCATGTCGCACGGCTTAATCGGGAGCAGGACACC
AGCCCGCTGATCCATCTGTTCAGTACGCAGCCGCGAACGCTGTACGATCTGCTCGACGTTCGCGCATTACTGGAGGGCGA
ATCGGCAAGGCTGGCGGCAACGCTGGGAACGCAGGCTGATTTTGTTGTGATAACCCGCTGTTATGAAAAAATGCTCGCCG
CCAGTGAGAACCACAAAGAGATTTCGCTGATCGAACATGCGCAGTTGGATCACGCTTTCCATCTCGCCATTTGTCAGGCT
TCTCACAATCAGGTGCTGGTGTTTACGCTGCAATCATTGACCGATCTGATGTTTAATTCAGTGTTTGCCAGCGTAAATGA
TCTCTACCATCGACCACAGCAAAAAAAGCAGATCGATCGCCAGCATGCGCGGATCTACAACGCGGTGTTGCAGCGGCTGC
CGCACGTCGCTCAGCGCGCAGCGCGCGATCATGTACGGACCGTGAAAAAGAATCTCCACGATATCGAGCTGGAAGGCCAC
CATTTGATTCGCTCGGCGGTGCCGCTGGAGATGAACAAGGTGGGAATGTGA

Upstream 100 bases:

>100_bases
ACTTAATGTTAAATTGATGTAACATAATCACTTGCGTGATGTGCGTGTTTTGCGAGTTAAGAACAGAAAAATTGGTCCTA
CCTGTGCACGAGGTCCGGGA

Downstream 100 bases:

>100_bases
GCAGAGTTTTACCCTATCCCCAAGGCGAGGGGACCGCCCCTGCACTTAACAGGATCTGGTGTTAAATCTGTTCATCTATA
CCCTCTCCCGAATGACCGCC

Product: DNA-binding transcriptional regulator GlcC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRDSHVARLNREQDT
SPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQADFVVITRCYEKMLAASENHKEISLIEHAQLDHAFHLAICQA
SHNQVLVFTLQSLTDLMFNSVFASVNDLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HLIRSAVPLEMNKVGM

Sequences:

>Translated_256_residues
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRDSHVARLNREQDT
SPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQADFVVITRCYEKMLAASENHKEISLIEHAQLDHAFHLAICQA
SHNQVLVFTLQSLTDLMFNSVFASVNDLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HLIRSAVPLEMNKVGM
>Mature_256_residues
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRDSHVARLNREQDT
SPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQADFVVITRCYEKMLAASENHKEISLIEHAQLDHAFHLAICQA
SHNQVLVFTLQSLTDLMFNSVFASVNDLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HLIRSAVPLEMNKVGM

Specific function: Activator for the glycolate oxidation locus [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789353, Length=252, Percent_Identity=98.4126984126984, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1786303, Length=231, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790032, Length=253, Percent_Identity=30.0395256916996, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790780, Length=251, Percent_Identity=29.8804780876494, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI48994955, Length=223, Percent_Identity=26.9058295964126, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082208, Length=232, Percent_Identity=24.5689655172414, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29077; Mature: 29077

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCC
IETAQGRDSHVARLNREQDTSPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQAD
EECCCCCHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCHHEEHHHCCCCC
FVVITRCYEKMLAASENHKEISLIEHAQLDHAFHLAICQASHNQVLVFTLQSLTDLMFNS
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHH
VFASVNDLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
HLIRSAVPLEMNKVGM
HHHHHCCCCCHHCCCC
>Mature Secondary Structure
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCC
IETAQGRDSHVARLNREQDTSPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQAD
EECCCCCHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCHHEEHHHCCCCC
FVVITRCYEKMLAASENHKEISLIEHAQLDHAFHLAICQASHNQVLVFTLQSLTDLMFNS
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHH
VFASVNDLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
HLIRSAVPLEMNKVGM
HHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]