Click here to switch to the map view.

The map label for this gene is mokC [H]

Identifier: 30063429

GI number: 30063429

Start: 2039294

End: 2039506

Strand: Reverse

Name: mokC [H]

Synonym: S2143

Alternate gene names: 30063429

Gene position: 2039506-2039294 (Counterclockwise)

Preceding gene: 30063430

Following gene: 30063427

Centisome position: 44.34

GC content: 51.17

Gene sequence:

>213_bases
ATGCTGAACACATGTAGGTTAGCCTCTTACGTGCCGAAAGGCAAGGAGAAGCAGGCTATGAAGCAGCAAAAGGCGATGTT
AATCGCCCTTATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAAAGACCTCTGCGAGGTACGAATCC
GAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Upstream 100 bases:

>100_bases
TATCTGTCTCAGGCATGAACACCAAAAGGCAGATAGAGAAAAGCCCCAGTTAACATTACGCGTCCTGCAAGACGCTTAAC
ATTAATCTGAGGCTCAATCC

Downstream 100 bases:

>100_bases
GAGACCCGGCGGGGGAGAAATCCCTCGCCACCGCTGATGTGTCAGGCATCCTCAACGCACCCGCACTTAACCCGCTTCGG
CGGGTTTTGTTTTTTCTGGT

Product: putative cell killing protein of prophage

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 70; Mature: 70

Protein sequence:

>70_residues
MLNTCRLASYVPKGKEKQAMKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEPEE

Sequences:

>Translated_70_residues
MLNTCRLASYVPKGKEKQAMKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEPEE
>Mature_70_residues
MLNTCRLASYVPKGKEKQAMKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEPEE

Specific function: Overlapping regulatory peptide whose translation enables hokC expression (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family [H]

Homologues:

Organism=Escherichia coli, GI1786200, Length=69, Percent_Identity=75.3623188405797, Blast_Score=104, Evalue=1e-24,
Organism=Escherichia coli, GI1787845, Length=51, Percent_Identity=100, Blast_Score=101, Evalue=1e-23,
Organism=Escherichia coli, GI48994874, Length=50, Percent_Identity=82, Blast_Score=87, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000021
- InterPro:   IPR018084
- ProDom:   PD005979 [H]

Pfam domain/function: PF01848 HOK_GEF [H]

EC number: NA

Molecular weight: Translated: 7857; Mature: 7857

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTCRLASYVPKGKEKQAMKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEV
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AVFTAYEPEE
EEEECCCCCC
>Mature Secondary Structure
MLNTCRLASYVPKGKEKQAMKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEV
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AVFTAYEPEE
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1943701; 9278503; 10361310 [H]