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The map label for this gene is tehB

Identifier: 30062901

GI number: 30062901

Start: 1455972

End: 1456565

Strand: Direct

Name: tehB

Synonym: S1494

Alternate gene names: 30062901

Gene position: 1455972-1456565 (Clockwise)

Preceding gene: 30062900

Following gene: 30062902

Centisome position: 31.66

GC content: 45.96

Gene sequence:

>594_bases
ATGATCATTCGTGACGAAAACTATTTTACTGATAAATATGAATTAACCCGCACACACTCTGAAGTACTGGAAGCGGTGAA
AGTGGTTAAACCGGGTAAAACGCTGGATCTGGGCTGTGGCAATGGTCGTAACAGTCTTTACCTGGCAGCCAATGGTTATG
ATGTTGACGCATGGGATAAAAATGCCATGAGTATCGCCAACGTCGAGCGCATTAAATCCATTGAAAATCTGGATAATTTA
CACACCCGGGTCGTTGATCTGAATAACCTCACATTTGATGGACAGTACGATTTTATTCTTTCGACTGTGGTGCTGATGTT
CCTTGAGGCTAAAACCATCCCAGGGTTGATTGCCAATATGCAACGTTGCACTAAACCTGGTGGTTACAACCTGATTGTGG
CGGCGATGGATACCGCTGATTATCCATGTACCGTCGGCTTCACGTTTGCCTTCAAAGAGGGAGAATTACGTCGATATTAC
GAAGGCTGGGAGAGGGTGAAATACAATGAAGACGTCGGCGAGCTGCACCGCACCGACGCCAACGGTAATCGTATTAAACT
GCGTTTCGCCACGATGCTGGCACGTAAAAAATGA

Upstream 100 bases:

>100_bases
TTATTGCAATACTGCTCATCCGTACTTTTGCGCTTCTGATGCAGGGAAAATTGTTAGTCAGAACCGAGCGCGCCGTTTTA
ATGAAAGCAGAGGACAAAGA

Downstream 100 bases:

>100_bases
CCCGGTAAGCACAAAACGCGTGAAAATTCCCCACGCTGAGATGATTTACTGTTCTTCTTTTCGGTAAGCATATTTTTTAT
CGAAGGGATGTGAAATTAAT

Product: tellurite resistance protein TehB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNL
HTRVVDLNNLTFDGQYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFTFAFKEGELRRYY
EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK

Sequences:

>Translated_197_residues
MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNL
HTRVVDLNNLTFDGQYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFTFAFKEGELRRYY
EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK
>Mature_197_residues
MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNL
HTRVVDLNNLTFDGQYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFTFAFKEGELRRYY
EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK

Specific function: Probable S-adenosyl-L-methionine dependent methyltransferase that is responsible for tellurite resistance when present in high copy number. Binds tellurite and S-adenosyl- L-methionine [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable). Note=Probably a peripheral membrane protein that interacts with TehA [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TehB family [H]

Homologues:

Organism=Escherichia coli, GI1787700, Length=197, Percent_Identity=98.9847715736041, Blast_Score=403, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004537
- InterPro:   IPR015985 [H]

Pfam domain/function: PF03848 TehB [H]

EC number: NA

Molecular weight: Translated: 22436; Mature: 22436

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDK
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCC
NAMSIANVERIKSIENLDNLHTRVVDLNNLTFDGQYDFILSTVVLMFLEAKTIPGLIANM
CCHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHH
QRCTKPGGYNLIVAAMDTADYPCTVGFTFAFKEGELRRYYEGWERVKYNEDVGELHRTDA
HHHCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHEECCCCHHHHHCCCC
NGNRIKLRFATMLARKK
CCCEEEEEEEHHHHCCC
>Mature Secondary Structure
MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDK
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCC
NAMSIANVERIKSIENLDNLHTRVVDLNNLTFDGQYDFILSTVVLMFLEAKTIPGLIANM
CCHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHH
QRCTKPGGYNLIVAAMDTADYPCTVGFTFAFKEGELRRYYEGWERVKYNEDVGELHRTDA
HHHCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHEECCCCHHHHHCCCC
NGNRIKLRFATMLARKK
CCCEEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2060788; 9097039; 9278503; 8169225 [H]