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The map label for this gene is ybbS

Identifier: 30061996

GI number: 30061996

Start: 460827

End: 461753

Strand: Reverse

Name: ybbS

Synonym: S0450

Alternate gene names: 30061996

Gene position: 461753-460827 (Counterclockwise)

Preceding gene: 30062001

Following gene: 30061995

Centisome position: 10.04

GC content: 51.67

Gene sequence:

>927_bases
ATGTTCGATCCAGAAACCTTGCGGACTTTCATTGCGGTTGCTGAAACAGGAAGTTTTTCAAAAGCGGCAGAACGATTATG
TAAAACCACGGCGACGATCAGTTATCGCATTAAACTTCTGGAAGAGAATACCGGAGTAGCGCTGTTTTTCCGTACGACTC
GTAGCGTAACGTTGACAGCGGCTGGCGAGCATCTACTTTCCCAGGCCAGAGACTGGCTGAGCTGGCTGGAAAGTATGCCC
AGCGAGCTGCAACAGGTGAATGATGGCGTGGAACGCCAGGTGAATATTGTCATCAACAACCTGCTCTATAACCCCCAGGC
CGTCGCCCAGTTGCTGGCGTGGCTGAATGAGCGTTACCCCTTTACCCAGTTTCACATCTCCCGACAAATCTATATGGGCG
TCTGGGACTCGCTATTGTACGAAGGTTTTTCGCTGGCTATCGGGGTCACGGGAACTGAGGCGCTGGCAAATACCTTTAGT
CTTGATCCCTTAGGATCGGTGCAATGGCGATTTGTCATGGCGGCGGATCATCCGCTGGCGAACGTTGAAGAGCCGCTAAC
AGAAGCGCAGTTGCGTCGCTTTCCGGCGGTCAATATTGAAGACAGCGCCGGCACCTTAACCAAACGCGTCGCCTGGCGAT
TGCCGGGGCAAAAAGAGATTATTGTTCCCGATATGGAAACGAAAATCGCCGCCCATCTGGCGGGTGTTGGCATTGGTTTT
TTGCCAAAATCACTTTGCCAGTCAATGATCGATAATCAACAACTGGTCAGCCGGGTAATCCCAACGATGCGCCCTCCTTC
GCCATTGAGTCTGGCATGGCGCAAATTTGGCAGCTGCAAAGCGGTAGAAGATATTGTGACCTTGTTTACCCAACACAGGC
CGGAAATCAGCGGATTTTTAGAAATTTTCGGCACCCCACGCAGTTAA

Upstream 100 bases:

>100_bases
TTTAGTCCACAAATTGAACAGGATTATCATGTAAAAATACTGATAAATCAGAGGATAAGAAAATCACGCAACTTGCGGAT
TTAAAAGGGGATACCTGAAG

Downstream 100 bases:

>100_bases
AAATCAAGTTTCCTTGCGCGTTGGCGCGTAAAATAGCGCGCAAGCTGATTTGAGGTTCACTTTTAACTATGCAAGAGAGA
CACACGGAACAGGACTATCG

Product: DNA-binding transcriptional activator AllS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMP
SELQQVNDGVERQVNIVINNLLYNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSAGTLTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGF
LPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKFGSCKAVEDIVTLFTQHRPEISGFLEIFGTPRS

Sequences:

>Translated_308_residues
MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMP
SELQQVNDGVERQVNIVINNLLYNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSAGTLTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGF
LPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKFGSCKAVEDIVTLFTQHRPEISGFLEIFGTPRS
>Mature_308_residues
MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMP
SELQQVNDGVERQVNIVINNLLYNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSAGTLTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGF
LPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKFGSCKAVEDIVTLFTQHRPEISGFLEIFGTPRS

Specific function: Positive regulator essential for the expression of AllD operon. Binds to the AllD promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786713, Length=308, Percent_Identity=98.7012987012987, Blast_Score=622, Evalue=1e-180,
Organism=Escherichia coli, GI1786508, Length=272, Percent_Identity=39.7058823529412, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1787949, Length=275, Percent_Identity=30.5454545454545, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI87082024, Length=271, Percent_Identity=24.7232472324723, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1789492, Length=293, Percent_Identity=26.2798634812287, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=249, Percent_Identity=30.1204819277108, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787879, Length=258, Percent_Identity=28.2945736434109, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=32.5, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787128, Length=305, Percent_Identity=26.8852459016393, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI157672245, Length=175, Percent_Identity=29.1428571428571, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34427; Mature: 34427

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRTTRSVTLTA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEEEECCCCEEEEEEECCCEEEEH
AGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLLYNPQAVAQLLAWLNERYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
FTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFSLDPLGSVQWRFVMAADHPLA
CHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCCCEEEEEEECCCCCC
NVEEPLTEAQLRRFPAVNIEDSAGTLTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGF
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCHHH
LPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKFGSCKAVEDIVTLFTQHRPEISGFL
HHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH
EIFGTPRS
HHHCCCCC
>Mature Secondary Structure
MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRTTRSVTLTA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEEEECCCCEEEEEEECCCEEEEH
AGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLLYNPQAVAQLLAWLNERYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
FTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFSLDPLGSVQWRFVMAADHPLA
CHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCCCEEEEEEECCCCCC
NVEEPLTEAQLRRFPAVNIEDSAGTLTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGF
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCHHH
LPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKFGSCKAVEDIVTLFTQHRPEISGFL
HHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH
EIFGTPRS
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]