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The map label for this gene is gluP [H]

Identifier: 29349719

GI number: 29349719

Start: 5681519

End: 5682679

Strand: Reverse

Name: gluP [H]

Synonym: BT_4311

Alternate gene names: 29349719

Gene position: 5682679-5681519 (Counterclockwise)

Preceding gene: 29349720

Following gene: 29349718

Centisome position: 90.77

GC content: 44.44

Gene sequence:

>1161_bases
ATGTTCTTTTCACTGGGCTTCGCCCTTGGTATCAACTCAGTATTAGTCCCCGTATTGAAGGGATCACTGGAAATCAGTTC
GGCCGAATCATATCTGATCATTGCCGCCACTTTCATCCCGTTCCTTATTTTTGGTTATCCGGCAGGCCTTACAATCAAAA
AAATCGGATACAAACGAACAATGGTCCTTTCATTCCTTATGTTTGCCATAGCCTTCGGACTTTTCATACCATCGGCAAGT
TATGAAAGTTTTCCTCTGTTTTTATTGGCTTCCTTTATCAGCGGAAGTGCCAACGCTTATCTGCAAGCTGCTGTAAACCC
GTATATCACGATTCTGGGACCGATAGACAGTGCTGCCAAACGTATCAGCATTATGGGTATATGCAACAAACTCGCATGGC
CGATTCCTCCTTTATTCCTGGCTTTCCTAATCGGAAAAGAAGTGACCGATATTACAGTAGCTGACCTGTTTCTGCCATTC
TACGTTATTATCGCCGCATTCATCGCACTAGGTATTATCGCATACATGGCTCCCCTACCGGAAGTCAAAGCCGTCGGTGA
AGACGACAGCGAAGAGGCAGCCGAAGCCTGTCCGTACGCCGCAAAGAAAACCTCCATCTGGCAATTCCCGCATTTATTAT
TAGGATGTCTTGCTCTCTTCTTATATGTAGGTGTAGAAACCGTATCACTGGGTACATTAGTAGATTATGCCACCAGCCTT
CATTTGGAAAATGCAGCAATGTATGCCTGGATTGCCCCGATAGGCATTGTGATCGGTTACATCTGCGGCATCATCTTCAT
CCCTAAATATATGAGCCAGGCTACAGCACTGAAGATTTGTTCAGTGCTGGCTATCATCGGTTCCGTACTAGTAGTACTTA
CACCTGCCGATATATCCATCTATTTCATCTCATTTATGGCATTGGGATGTTCTTTAATGTGGCCTGCCCTATGGCCTTTG
GCTATGGCAGATTTAGGAAAGTTCACCAAATCCGGTTCATCTCTTCTGATCATGGCAATGGCAGGCGGTGCTGTTATTCC
GACCTTATTTGGCTATCTGAAAGACATTTCCGATATTCAGAAAGCATATTGGATTTGCCTTCCCTGCTTCCTGTTTATTC
TATATTATGGGGTAGCCGGATACAAAATCAGAACGAAATAA

Upstream 100 bases:

>100_bases
CTGCCCCTTACAGGAGTTTCCTTTATTAACCTTTAACACATTTACCCCCATGACAAAAAACACAAAAAGTTTCGTATTGC
CATTGGCATTCATTGGCGTT

Downstream 100 bases:

>100_bases
ATAAAGATATTCACATGGATATGGAAAGTCACTCATCAAAAGAGTGACTTTTCTTTTTATATTTCGTAAATAAGCCGTAT
CTTTGCCGAAATTTATAACA

Product: glucose/galactose transporter

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MFFSLGFALGINSVLVPVLKGSLEISSAESYLIIAATFIPFLIFGYPAGLTIKKIGYKRTMVLSFLMFAIAFGLFIPSAS
YESFPLFLLASFISGSANAYLQAAVNPYITILGPIDSAAKRISIMGICNKLAWPIPPLFLAFLIGKEVTDITVADLFLPF
YVIIAAFIALGIIAYMAPLPEVKAVGEDDSEEAAEACPYAAKKTSIWQFPHLLLGCLALFLYVGVETVSLGTLVDYATSL
HLENAAMYAWIAPIGIVIGYICGIIFIPKYMSQATALKICSVLAIIGSVLVVLTPADISIYFISFMALGCSLMWPALWPL
AMADLGKFTKSGSSLLIMAMAGGAVIPTLFGYLKDISDIQKAYWICLPCFLFILYYGVAGYKIRTK

Sequences:

>Translated_386_residues
MFFSLGFALGINSVLVPVLKGSLEISSAESYLIIAATFIPFLIFGYPAGLTIKKIGYKRTMVLSFLMFAIAFGLFIPSAS
YESFPLFLLASFISGSANAYLQAAVNPYITILGPIDSAAKRISIMGICNKLAWPIPPLFLAFLIGKEVTDITVADLFLPF
YVIIAAFIALGIIAYMAPLPEVKAVGEDDSEEAAEACPYAAKKTSIWQFPHLLLGCLALFLYVGVETVSLGTLVDYATSL
HLENAAMYAWIAPIGIVIGYICGIIFIPKYMSQATALKICSVLAIIGSVLVVLTPADISIYFISFMALGCSLMWPALWPL
AMADLGKFTKSGSSLLIMAMAGGAVIPTLFGYLKDISDIQKAYWICLPCFLFILYYGVAGYKIRTK
>Mature_386_residues
MFFSLGFALGINSVLVPVLKGSLEISSAESYLIIAATFIPFLIFGYPAGLTIKKIGYKRTMVLSFLMFAIAFGLFIPSAS
YESFPLFLLASFISGSANAYLQAAVNPYITILGPIDSAAKRISIMGICNKLAWPIPPLFLAFLIGKEVTDITVADLFLPF
YVIIAAFIALGIIAYMAPLPEVKAVGEDDSEEAAEACPYAAKKTSIWQFPHLLLGCLALFLYVGVETVSLGTLVDYATSL
HLENAAMYAWIAPIGIVIGYICGIIFIPKYMSQATALKICSVLAIIGSVLVVLTPADISIYFISFMALGCSLMWPALWPL
AMADLGKFTKSGSSLLIMAMAGGAVIPTLFGYLKDISDIQKAYWICLPCFLFILYYGVAGYKIRTK

Specific function: Intake of glucose and galactose (Potential) [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=412, Percent_Identity=23.3009708737864, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005964
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41722; Mature: 41722

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFSLGFALGINSVLVPVLKGSLEISSAESYLIIAATFIPFLIFGYPAGLTIKKIGYKRT
CEEEHHHHHHHHHHHHHHHHCCCEECCCCCCEEHHHHHHHHHHHCCCCCCEEEHHCHHHH
MVLSFLMFAIAFGLFIPSASYESFPLFLLASFISGSANAYLQAAVNPYITILGPIDSAAK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHEEECCCEEEEEECCHHHHH
RISIMGICNKLAWPIPPLFLAFLIGKEVTDITVADLFLPFYVIIAAFIALGIIAYMAPLP
HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EVKAVGEDDSEEAAEACPYAAKKTSIWQFPHLLLGCLALFLYVGVETVSLGTLVDYATSL
CHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLENAAMYAWIAPIGIVIGYICGIIFIPKYMSQATALKICSVLAIIGSVLVVLTPADISI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
YFISFMALGCSLMWPALWPLAMADLGKFTKSGSSLLIMAMAGGAVIPTLFGYLKDISDIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
KAYWICLPCFLFILYYGVAGYKIRTK
HHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MFFSLGFALGINSVLVPVLKGSLEISSAESYLIIAATFIPFLIFGYPAGLTIKKIGYKRT
CEEEHHHHHHHHHHHHHHHHCCCEECCCCCCEEHHHHHHHHHHHCCCCCCEEEHHCHHHH
MVLSFLMFAIAFGLFIPSASYESFPLFLLASFISGSANAYLQAAVNPYITILGPIDSAAK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHEEECCCEEEEEECCHHHHH
RISIMGICNKLAWPIPPLFLAFLIGKEVTDITVADLFLPFYVIIAAFIALGIIAYMAPLP
HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EVKAVGEDDSEEAAEACPYAAKKTSIWQFPHLLLGCLALFLYVGVETVSLGTLVDYATSL
CHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLENAAMYAWIAPIGIVIGYICGIIFIPKYMSQATALKICSVLAIIGSVLVVLTPADISI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
YFISFMALGCSLMWPALWPLAMADLGKFTKSGSSLLIMAMAGGAVIPTLFGYLKDISDIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
KAYWICLPCFLFILYYGVAGYKIRTK
HHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168605 [H]