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The map label for this gene is comEB [H]

Identifier: 29349668

GI number: 29349668

Start: 5610663

End: 5611112

Strand: Reverse

Name: comEB [H]

Synonym: BT_4260

Alternate gene names: 29349668

Gene position: 5611112-5610663 (Counterclockwise)

Preceding gene: 29349669

Following gene: 29349667

Centisome position: 89.63

GC content: 45.11

Gene sequence:

>450_bases
ATGGACACGGAAAAGAAACAATTGGAACTGGACAAACGTTACATACGTATGGCAAGCATCTGGGCGGAAAACTCTTATTG
CCAGCGCCGTAAGGTAGGAGCGTTGATCGTCAAAGACAAAATGATTATCTCCGACGGATACAATGGTACTCCTTCGGGCT
TCGAAAACGTATGCGAGGACGAGAATAACCTGACAAAACCTTATGTTCTCCATGCGGAAGCAAACGCTATCACCAAGATA
GCACGCTCGAACAACAGCAGCGACGGTGCCACGATGTACGTCACCGCCTCACCTTGTATCGAATGTGCAAAGTTAATCAT
ACAGGCAGGAATCAAACGGGTAGTCTACTCCGAACATTACCGCCTCGAAGATGGAATAGAACTATTAAAACGGGCAGGAA
TCGAAGTTATCTATACAGAAATGAACGAAGATTCTTCTCCAAACAAATAA

Upstream 100 bases:

>100_bases
ACGGAGGAGATGAGCGAAATCTATACCTTTACTATAAACCTTCCGGTAGCCAGCAGACACTTTCTTTAGTTTTTCACGTT
GTAAAATAAAAGACACTCTC

Downstream 100 bases:

>100_bases
TAAAACGAACGTTTTAAAAAAAGGAATAGACATGAGTACAAGAAACTCTTCACGTTTTACGCCTATCATCATAGCTATCA
GCGTGGTGGCCGGTATTCTT

Product: deoxycytidylate deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MDTEKKQLELDKRYIRMASIWAENSYCQRRKVGALIVKDKMIISDGYNGTPSGFENVCEDENNLTKPYVLHAEANAITKI
ARSNNSSDGATMYVTASPCIECAKLIIQAGIKRVVYSEHYRLEDGIELLKRAGIEVIYTEMNEDSSPNK

Sequences:

>Translated_149_residues
MDTEKKQLELDKRYIRMASIWAENSYCQRRKVGALIVKDKMIISDGYNGTPSGFENVCEDENNLTKPYVLHAEANAITKI
ARSNNSSDGATMYVTASPCIECAKLIIQAGIKRVVYSEHYRLEDGIELLKRAGIEVIYTEMNEDSSPNK
>Mature_149_residues
MDTEKKQLELDKRYIRMASIWAENSYCQRRKVGALIVKDKMIISDGYNGTPSGFENVCEDENNLTKPYVLHAEANAITKI
ARSNNSSDGATMYVTASPCIECAKLIIQAGIKRVVYSEHYRLEDGIELLKRAGIEVIYTEMNEDSSPNK

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742821, Length=128, Percent_Identity=40.625, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI61742819, Length=128, Percent_Identity=40.625, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17557019, Length=132, Percent_Identity=37.1212121212121, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321938, Length=152, Percent_Identity=36.1842105263158, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 16800; Mature: 16800

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTEKKQLELDKRYIRMASIWAENSYCQRRKVGALIVKDKMIISDGYNGTPSGFENVCED
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECEEEEECCCCCCCHHHHHHHCC
ENNLTKPYVLHAEANAITKIARSNNSSDGATMYVTASPCIECAKLIIQAGIKRVVYSEHY
CCCCCCCEEEEECHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
RLEDGIELLKRAGIEVIYTEMNEDSSPNK
CCHHHHHHHHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MDTEKKQLELDKRYIRMASIWAENSYCQRRKVGALIVKDKMIISDGYNGTPSGFENVCED
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECEEEEECCCCCCCHHHHHHHCC
ENNLTKPYVLHAEANAITKIARSNNSSDGATMYVTASPCIECAKLIIQAGIKRVVYSEHY
CCCCCCCEEEEECHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
RLEDGIELLKRAGIEVIYTEMNEDSSPNK
CCHHHHHHHHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]