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The map label for this gene is lytT [H]

Identifier: 29349374

GI number: 29349374

Start: 5162880

End: 5163671

Strand: Reverse

Name: lytT [H]

Synonym: BT_3966

Alternate gene names: 29349374

Gene position: 5163671-5162880 (Counterclockwise)

Preceding gene: 29349375

Following gene: 29349350

Centisome position: 82.48

GC content: 44.07

Gene sequence:

>792_bases
ATGAAAACAGTTATTATTGAAGATGAAAAGGCAGCCGTACGCAATCTGACTTCACTGCTCAACGAAGTGAAACCGGAAGC
TGAAATCATTGCCATACTGGACAGCATCAATTCCACCATCGAATGGTTCGGCATCCACCCGATGCCGGAACTCGTTTTTA
TGGATATTCATCTGGCAGACGGTTCTGCCTTCGAAATATTCGATCATATCAGCATCACCTGCCCCATTATCTTCACCACG
GCTTACGACGAATATGCCCTGCGTGCCTTCAAAGTGAACAGTATCGACTATCTGCTGAAACCTATCGGCAAGGAGGACAT
CGAACATGCGTTTGAGAAATTGGACAACTTGCAGGATGCCATCCCCGAAAACGGAAGCAAGCGGGAAAATAAGGAAGAGG
AACTGCTTCATCTCATTCACTCGCTGAAAAAGCAGGAGAACTACAAGACACATTTCCTCATACCGATGAAAGGCGATAAG
CTGCTTCCTGTCTCAATCGACATGATTCAACTGTTCTACATCAAAGATTGTCAGGTAAAAGCTGTCTTAACGGACGGGAT
GGAATACAATTTTTCTCTTACGCTGGATGAATTGGTCGATTGTTTAAATCCTAGTCTCTTCTTCAGAGTCAACCGGCAGT
TTCTGATTTCAAGGGAGGCGATAAAGGATATTGATTTATGGTTCAACAGCCGGTTGTCCATTAATCTGCGTCACTCCAGA
ATGACAGAGAAGATATTGGTAAGCAAAGCACGGGTAGCGGAATTTAAGGAATGGTTTTCGAGCAAAAAGTAA

Upstream 100 bases:

>100_bases
GGCTATTATTCAAACAGGACATACAGATCACAGAGGACAAAGAATTCACCGTCTGCATTCCTCTCATTGATGAAGTACAA
TGAAGTAAGAACAATGAACC

Downstream 100 bases:

>100_bases
AACAAGCGGGACTATATTGAAATCCCGCTTATATGCATTCGTTCTTTATAAGTATCGGATATCAGTTCTAAAAAAAGGAT
GAAGCCCAGCCTCATCCTTT

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKTVIIEDEKAAVRNLTSLLNEVKPEAEIIAILDSINSTIEWFGIHPMPELVFMDIHLADGSAFEIFDHISITCPIIFTT
AYDEYALRAFKVNSIDYLLKPIGKEDIEHAFEKLDNLQDAIPENGSKRENKEEELLHLIHSLKKQENYKTHFLIPMKGDK
LLPVSIDMIQLFYIKDCQVKAVLTDGMEYNFSLTLDELVDCLNPSLFFRVNRQFLISREAIKDIDLWFNSRLSINLRHSR
MTEKILVSKARVAEFKEWFSSKK

Sequences:

>Translated_263_residues
MKTVIIEDEKAAVRNLTSLLNEVKPEAEIIAILDSINSTIEWFGIHPMPELVFMDIHLADGSAFEIFDHISITCPIIFTT
AYDEYALRAFKVNSIDYLLKPIGKEDIEHAFEKLDNLQDAIPENGSKRENKEEELLHLIHSLKKQENYKTHFLIPMKGDK
LLPVSIDMIQLFYIKDCQVKAVLTDGMEYNFSLTLDELVDCLNPSLFFRVNRQFLISREAIKDIDLWFNSRLSINLRHSR
MTEKILVSKARVAEFKEWFSSKK
>Mature_263_residues
MKTVIIEDEKAAVRNLTSLLNEVKPEAEIIAILDSINSTIEWFGIHPMPELVFMDIHLADGSAFEIFDHISITCPIIFTT
AYDEYALRAFKVNSIDYLLKPIGKEDIEHAFEKLDNLQDAIPENGSKRENKEEELLHLIHSLKKQENYKTHFLIPMKGDK
LLPVSIDMIQLFYIKDCQVKAVLTDGMEYNFSLTLDELVDCLNPSLFFRVNRQFLISREAIKDIDLWFNSRLSINLRHSR
MTEKILVSKARVAEFKEWFSSKK

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=264, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082052, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 30526; Mature: 30526

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVIIEDEKAAVRNLTSLLNEVKPEAEIIAILDSINSTIEWFGIHPMPELVFMDIHLAD
CCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECC
GSAFEIFDHISITCPIIFTTAYDEYALRAFKVNSIDYLLKPIGKEDIEHAFEKLDNLQDA
CCCEEHHHCCEEEEEEEEEECCHHHHHEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHH
IPENGSKRENKEEELLHLIHSLKKQENYKTHFLIPMKGDKLLPVSIDMIQLFYIKDCQVK
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEHHEEEEEEECCCEEE
AVLTDGMEYNFSLTLDELVDCLNPSLFFRVNRQFLISREAIKDIDLWFNSRLSINLRHSR
EEEECCCEEEEEEEHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHCCCEEEEEEHHHH
MTEKILVSKARVAEFKEWFSSKK
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKTVIIEDEKAAVRNLTSLLNEVKPEAEIIAILDSINSTIEWFGIHPMPELVFMDIHLAD
CCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECC
GSAFEIFDHISITCPIIFTTAYDEYALRAFKVNSIDYLLKPIGKEDIEHAFEKLDNLQDA
CCCEEHHHCCEEEEEEEEEECCHHHHHEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHH
IPENGSKRENKEEELLHLIHSLKKQENYKTHFLIPMKGDKLLPVSIDMIQLFYIKDCQVK
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEHHEEEEEEECCCEEE
AVLTDGMEYNFSLTLDELVDCLNPSLFFRVNRQFLISREAIKDIDLWFNSRLSINLRHSR
EEEECCCEEEEEEEHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHCCCEEEEEEHHHH
MTEKILVSKARVAEFKEWFSSKK
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]