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The map label for this gene is atpA [H]

Identifier: 29346709

GI number: 29346709

Start: 1619403

End: 1621160

Strand: Reverse

Name: atpA [H]

Synonym: BT_1299

Alternate gene names: 29346709

Gene position: 1621160-1619403 (Counterclockwise)

Preceding gene: 29346710

Following gene: 29346708

Centisome position: 25.9

GC content: 44.77

Gene sequence:

>1758_bases
ATGGCAACAAAAGGAACTGTTAGTGGCGTTATTGCCAACATGGTGACCCTCGTCGTTGACGGCCCGGTAGCTCAGAATGA
GATTTGTTATATCTCTACCGGTGGCGATAGATTGATGGCGGAGGTGATTAAGGTTGTAGGTTCGCATGTGTATGTTCAGG
TGTTCGAAAGCACACGTGGACTGAAGGTGGGCGCCGAAGCCGAATTTACAGGACACATGCTTGAAGTGACCTTGGGTCCG
GGTATGTTATCGAAAAACTATGACGGTCTGCAAAACGACCTTGACAAGATGGACGGTGTTTTCCTGAAAAGAGGACAATA
TACATATCCGTTGGATAAAGAACGTATATGGCATTTTGTTCCGATGGTGAGCGCCGGTGATAAAGTGGTGGCTTCCGCAT
GGCTGGGACAAGTGGATGAAAACTTCCAGCCGCTGAAAATTATGGCTCCGTTTACTATGAATGGAACGGCTACCGTAAAA
ACGATTATGCCCGAAGGGGATTATAAAATAGAAGATACAATTGCTATTCTGACAGACGAGGAAGGAAATGACATTCCGGT
GACTATGATTCAGAAATGGCCGGTGAAACGGGCTATGACGAATTATAAAGAAAAACCGCGTCCTTTCAAATTGTTGGAGA
CCGGTGTACGTGTTATTGATACGCTGAACCCGATTGTAGAAGGTGGTACAGGATTTATCCCCGGTCCGTTCGGTACAGGC
AAGACAGTGCTTCAGCATGCTATTTCCAAACAGGCAGAAGCGGATATCGTAATTATCGCGGCTTGTGGTGAACGTGCCAA
CGAGGTAGTGGAAATCTTTACAGAATTCCCGGAATTGGTGGACCCGCATACAGGACGCAAATTGATGGAGCGTACCATTA
TTATTGCAAATACTTCAAACATGCCGGTAGCCGCCCGTGAAGCATCTGTATATACAGCAATGTCTTTGGCTGAGTATTAC
CGTTCGATGGGACTGAAGGTATTGCTGATGGCCGACTCTACTTCCCGTTGGGCACAGGCATTGCGTGAAATGTCCAACCG
TATGGAAGAATTGCCCGGACCGGATGCGTTCCCAATGGATATTTCTGCTATTATTTCTAACTTCTATGGCCGTGCAGGTT
ATGTAAAACTGAATAACGACGAGACCGGCTCAATTACTTTTATCGGTACGGTGTCACCTGCCGGAGGTAACTTGAAGGAG
CCTGTAACGGAAAACACAAAGAAGGTAGCCCGTTGTTTCTACGCACTGGAACAGGACCGTGCCGACAAGAAACGTTATCC
GGCTGTGAATCCGATTGACTCATATTCCAAATATATCGAATATCCGGAATTTGAAGAATATATCAAAGATCATATCAATG
ATGAATGGATCGGTAAAGTGAATGAGCTTAAAACCCGTTTGCAGCGTGGTAAAGAAATTGCCGAACAAATCAACATTCTG
GGTGATGACGGTGTACCTGTAGAATACCATGTTATCTTCTGGAAATCTGAACTGATCGACTTCGTAATCCTGCAGCAGGA
TGCCTTTGATGAGGTGGACTCGGTAACTCCGATGGAACGTCAGGAAGCTATCCTGAATATGATCATAGATATCTGTCATA
CAGAATTTGAATTTGAAAACTTCAATGAAGTAATGGATTACTTCAAGAAAATGATCAATGTCTGTAAGCAGATGAACTAC
TCGAAGTTCAAATCAGAGCAGTACGAAGGGTTCCAGCAGCAATTAAAAGAACTGATTGCCGAAAGAAGCGTTAAATAG

Upstream 100 bases:

>100_bases
ATAAGGAAAGAGGAAATCAATTGTTCCGAAGCATTATTGAATCGCTGAAGAATGAGGTACAGATTCCCGCAGAATTCAGA
TAATAAATTAAAAAAAATAT

Downstream 100 bases:

>100_bases
TAAATTGTAAATAGCTAAATCGTAAATATATAGATGGCAACAAAAGCTTTTCAAAAGATATATACCAAGATTACTCAGAT
TACCAAGGCTACTTGTTCGC

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MATKGTVSGVIANMVTLVVDGPVAQNEICYISTGGDRLMAEVIKVVGSHVYVQVFESTRGLKVGAEAEFTGHMLEVTLGP
GMLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERIWHFVPMVSAGDKVVASAWLGQVDENFQPLKIMAPFTMNGTATVK
TIMPEGDYKIEDTIAILTDEEGNDIPVTMIQKWPVKRAMTNYKEKPRPFKLLETGVRVIDTLNPIVEGGTGFIPGPFGTG
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMSLAEYY
RSMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMDISAIISNFYGRAGYVKLNNDETGSITFIGTVSPAGGNLKE
PVTENTKKVARCFYALEQDRADKKRYPAVNPIDSYSKYIEYPEFEEYIKDHINDEWIGKVNELKTRLQRGKEIAEQINIL
GDDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEAILNMIIDICHTEFEFENFNEVMDYFKKMINVCKQMNY
SKFKSEQYEGFQQQLKELIAERSVK

Sequences:

>Translated_585_residues
MATKGTVSGVIANMVTLVVDGPVAQNEICYISTGGDRLMAEVIKVVGSHVYVQVFESTRGLKVGAEAEFTGHMLEVTLGP
GMLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERIWHFVPMVSAGDKVVASAWLGQVDENFQPLKIMAPFTMNGTATVK
TIMPEGDYKIEDTIAILTDEEGNDIPVTMIQKWPVKRAMTNYKEKPRPFKLLETGVRVIDTLNPIVEGGTGFIPGPFGTG
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMSLAEYY
RSMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMDISAIISNFYGRAGYVKLNNDETGSITFIGTVSPAGGNLKE
PVTENTKKVARCFYALEQDRADKKRYPAVNPIDSYSKYIEYPEFEEYIKDHINDEWIGKVNELKTRLQRGKEIAEQINIL
GDDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEAILNMIIDICHTEFEFENFNEVMDYFKKMINVCKQMNY
SKFKSEQYEGFQQQLKELIAERSVK
>Mature_584_residues
ATKGTVSGVIANMVTLVVDGPVAQNEICYISTGGDRLMAEVIKVVGSHVYVQVFESTRGLKVGAEAEFTGHMLEVTLGPG
MLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERIWHFVPMVSAGDKVVASAWLGQVDENFQPLKIMAPFTMNGTATVKT
IMPEGDYKIEDTIAILTDEEGNDIPVTMIQKWPVKRAMTNYKEKPRPFKLLETGVRVIDTLNPIVEGGTGFIPGPFGTGK
TVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMSLAEYYR
SMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMDISAIISNFYGRAGYVKLNNDETGSITFIGTVSPAGGNLKEP
VTENTKKVARCFYALEQDRADKKRYPAVNPIDSYSKYIEYPEFEEYIKDHINDEWIGKVNELKTRLQRGKEIAEQINILG
DDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEAILNMIIDICHTEFEFENFNEVMDYFKKMINVCKQMNYS
KFKSEQYEGFQQQLKELIAERSVK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=539, Percent_Identity=37.4768089053803, Blast_Score=335, Evalue=6e-92,
Organism=Homo sapiens, GI32189394, Length=330, Percent_Identity=25.1515151515152, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI50345984, Length=230, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4757810, Length=230, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790170, Length=330, Percent_Identity=25.7575757575758, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790172, Length=238, Percent_Identity=26.890756302521, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788251, Length=227, Percent_Identity=28.1938325991189, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=539, Percent_Identity=37.4768089053803, Blast_Score=331, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI25144756, Length=285, Percent_Identity=25.6140350877193, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17510931, Length=306, Percent_Identity=23.8562091503268, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988080, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988063, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71988074, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320016, Length=278, Percent_Identity=38.8489208633094, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6322581, Length=356, Percent_Identity=25, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319603, Length=322, Percent_Identity=25.4658385093168, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319370, Length=230, Percent_Identity=25.2173913043478, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24583992, Length=534, Percent_Identity=36.7041198501873, Blast_Score=336, Evalue=3e-92,
Organism=Drosophila melanogaster, GI24583988, Length=534, Percent_Identity=35.7677902621723, Blast_Score=328, Evalue=7e-90,
Organism=Drosophila melanogaster, GI24583986, Length=534, Percent_Identity=35.7677902621723, Blast_Score=328, Evalue=7e-90,
Organism=Drosophila melanogaster, GI24583984, Length=534, Percent_Identity=35.7677902621723, Blast_Score=328, Evalue=7e-90,
Organism=Drosophila melanogaster, GI20129479, Length=541, Percent_Identity=35.1201478743068, Blast_Score=314, Evalue=9e-86,
Organism=Drosophila melanogaster, GI28574560, Length=295, Percent_Identity=28.135593220339, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24638766, Length=283, Percent_Identity=26.1484098939929, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 65803; Mature: 65672

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKGTVSGVIANMVTLVVDGPVAQNEICYISTGGDRLMAEVIKVVGSHVYVQVFESTRG
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHEEEEECCCCC
LKVGAEAEFTGHMLEVTLGPGMLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERIWHFV
EEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHH
PMVSAGDKVVASAWLGQVDENFQPLKIMAPFTMNGTATVKTIMPEGDYKIEDTIAILTDE
CCCCCCCHHHHHHHHHHHCCCCCCEEEEECEECCCCEEEEEECCCCCCEEECEEEEEECC
EGNDIPVTMIQKWPVKRAMTNYKEKPRPFKLLETGVRVIDTLNPIVEGGTGFIPGPFGTG
CCCCCCEEHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSN
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCEEEEEECCC
MPVAAREASVYTAMSLAEYYRSMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMD
CCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
ISAIISNFYGRAGYVKLNNDETGSITFIGTVSPAGGNLKEPVTENTKKVARCFYALEQDR
HHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHC
ADKKRYPAVNPIDSYSKYIEYPEFEEYIKDHINDEWIGKVNELKTRLQRGKEIAEQINIL
CHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCC
GDDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEAILNMIIDICHTEFEFEN
CCCCCCEEEEEEEEHHHHHHHHEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
FNEVMDYFKKMINVCKQMNYSKFKSEQYEGFQQQLKELIAERSVK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATKGTVSGVIANMVTLVVDGPVAQNEICYISTGGDRLMAEVIKVVGSHVYVQVFESTRG
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHEEEEECCCCC
LKVGAEAEFTGHMLEVTLGPGMLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERIWHFV
EEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHH
PMVSAGDKVVASAWLGQVDENFQPLKIMAPFTMNGTATVKTIMPEGDYKIEDTIAILTDE
CCCCCCCHHHHHHHHHHHCCCCCCEEEEECEECCCCEEEEEECCCCCCEEECEEEEEECC
EGNDIPVTMIQKWPVKRAMTNYKEKPRPFKLLETGVRVIDTLNPIVEGGTGFIPGPFGTG
CCCCCCEEHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSN
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCEEEEEECCC
MPVAAREASVYTAMSLAEYYRSMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMD
CCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
ISAIISNFYGRAGYVKLNNDETGSITFIGTVSPAGGNLKEPVTENTKKVARCFYALEQDR
HHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHC
ADKKRYPAVNPIDSYSKYIEYPEFEEYIKDHINDEWIGKVNELKTRLQRGKEIAEQINIL
CHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCC
GDDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEAILNMIIDICHTEFEFEN
CCCCCCEEEEEEEEHHHHHHHHEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
FNEVMDYFKKMINVCKQMNYSKFKSEQYEGFQQQLKELIAERSVK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA