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The map label for this gene is yajO [H]

Identifier: 29346525

GI number: 29346525

Start: 1401639

End: 1402793

Strand: Reverse

Name: yajO [H]

Synonym: BT_1115

Alternate gene names: 29346525

Gene position: 1402793-1401639 (Counterclockwise)

Preceding gene: 29346526

Following gene: 29346524

Centisome position: 22.41

GC content: 51.08

Gene sequence:

>1155_bases
ATGAGCCGCCGGAGATTCCTTAAAATGGCGGCATTGACAGGAGCTGCCATGTGTGTCGGGCCTACCTTGAACAAGGTAAC
GGCAGCAGAACGGGTATGGATGGGGAAACAACAAGTTGCAAACAACATCCCTGCAGGCATGGCGGCGGTGCGCACTCGGC
GAACATTGGGACACGGAAATACGGCATTCACTGTTTCTGCAATGGGATATGGCTGTATGGGCTTGAACCATAACCGCAGC
CAGTACCCGAGCAGGGAAAAAGAAATCGCCCTGGTGCATGAAGCTGTTGAACGTGGGGTGACCCTTTTCGATACAGCCGA
AAGCTACGGCTACCACATCAATGAAAAATTGGTCGGCGAAGCCTTGAAAGGATATACCGACCGGGTATTTGTGTCATCGA
AGTTCGGACATAAGTTTGTAAACGGTGTGCAGATTAAAACCGAAGAGGACAGCACTCCGGCCAACATCCGCCGGGTTTGT
GAAAACTCGTTGCGCAATCTCGGAGTTGAAACATTGGGCATGTTCTACCAGCACCGCATAGACCCGAACACACCGATTGA
AGCGGTGGCTGAAACATGCAGCAAACTCATCAAGGAAGGTAAAATCCTGCATTGGGGCATGTGTGAAGTAAACGTTGATA
CCATCCGCCGTGCGCACAAGATATGTCCGGTTACGGCAATCCAAAGCGAATATCACTTGATGCACCGCATGGTAGAGACG
AACGGAGTGTTGGAGCTGTGCGAGGATTTGGGCATCGGTTTCGTTCCATACAGTCCGCTGAACCGTGGTTTTTTGGGCGG
TATGATCAATGAATATACCAAGTTTGATGTTACCAACGACAACCGGCAGACCTTGCCACGCTTCCAGCCCGAAGCCATAC
GCGCCAACTATCGTATTGTGGAAGTTCTTAACGCTTTCGGCCGTACAAGAGGCATTACCCCGGCACAGATAGCTTTGGCC
TGGCTGATGAACAAGAAGCCTTTTATCGTGCCTATTCCGGGCACCACCAAACTCTCTCATCTAGAAGAGAACCTTCGTGC
CTGCGACATCCGTTTCACGGCAGAAGAGATAGAAGAACTGGAAACAGCCGTAGCTGCCATTCCTGTGGTGGGTAGCCGCT
ACGATGCCTTGCAGGAGTCTAAAATCCCAAAATAA

Upstream 100 bases:

>100_bases
GCTTAGATGATATATATCAAAAAAAGTTTATCAATTCTGTCACGTTAACTTTGCAACAGAAATAATTTAAAGACTATCAA
ATATGGATAAAGACAAGGAT

Downstream 100 bases:

>100_bases
TCCGTGTATGAAGAAACAGATATTTTACATGACGTTCATCGCTTTACTGTCGGGCTGTAATTGTTACAAAGGGAATATTC
TGCAAATAGAGGAACAAGGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSRRRFLKMAALTGAAMCVGPTLNKVTAAERVWMGKQQVANNIPAGMAAVRTRRTLGHGNTAFTVSAMGYGCMGLNHNRS
QYPSREKEIALVHEAVERGVTLFDTAESYGYHINEKLVGEALKGYTDRVFVSSKFGHKFVNGVQIKTEEDSTPANIRRVC
ENSLRNLGVETLGMFYQHRIDPNTPIEAVAETCSKLIKEGKILHWGMCEVNVDTIRRAHKICPVTAIQSEYHLMHRMVET
NGVLELCEDLGIGFVPYSPLNRGFLGGMINEYTKFDVTNDNRQTLPRFQPEAIRANYRIVEVLNAFGRTRGITPAQIALA
WLMNKKPFIVPIPGTTKLSHLEENLRACDIRFTAEEIEELETAVAAIPVVGSRYDALQESKIPK

Sequences:

>Translated_384_residues
MSRRRFLKMAALTGAAMCVGPTLNKVTAAERVWMGKQQVANNIPAGMAAVRTRRTLGHGNTAFTVSAMGYGCMGLNHNRS
QYPSREKEIALVHEAVERGVTLFDTAESYGYHINEKLVGEALKGYTDRVFVSSKFGHKFVNGVQIKTEEDSTPANIRRVC
ENSLRNLGVETLGMFYQHRIDPNTPIEAVAETCSKLIKEGKILHWGMCEVNVDTIRRAHKICPVTAIQSEYHLMHRMVET
NGVLELCEDLGIGFVPYSPLNRGFLGGMINEYTKFDVTNDNRQTLPRFQPEAIRANYRIVEVLNAFGRTRGITPAQIALA
WLMNKKPFIVPIPGTTKLSHLEENLRACDIRFTAEEIEELETAVAAIPVVGSRYDALQESKIPK
>Mature_383_residues
SRRRFLKMAALTGAAMCVGPTLNKVTAAERVWMGKQQVANNIPAGMAAVRTRRTLGHGNTAFTVSAMGYGCMGLNHNRSQ
YPSREKEIALVHEAVERGVTLFDTAESYGYHINEKLVGEALKGYTDRVFVSSKFGHKFVNGVQIKTEEDSTPANIRRVCE
NSLRNLGVETLGMFYQHRIDPNTPIEAVAETCSKLIKEGKILHWGMCEVNVDTIRRAHKICPVTAIQSEYHLMHRMVETN
GVLELCEDLGIGFVPYSPLNRGFLGGMINEYTKFDVTNDNRQTLPRFQPEAIRANYRIVEVLNAFGRTRGITPAQIALAW
LMNKKPFIVPIPGTTKLSHLEENLRACDIRFTAEEIEELETAVAAIPVVGSRYDALQESKIPK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=342, Percent_Identity=25.1461988304094, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI27436964, Length=328, Percent_Identity=25.3048780487805, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436966, Length=328, Percent_Identity=25.3048780487805, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436969, Length=331, Percent_Identity=25.0755287009063, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4504825, Length=331, Percent_Identity=25.0755287009063, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI27436971, Length=348, Percent_Identity=25.2873563218391, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=32.3076923076923, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1789375, Length=311, Percent_Identity=25.7234726688103, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787674, Length=306, Percent_Identity=27.1241830065359, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788070, Length=308, Percent_Identity=28.8961038961039, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788081, Length=314, Percent_Identity=26.4331210191083, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325384, Length=340, Percent_Identity=28.2352941176471, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323998, Length=296, Percent_Identity=23.9864864864865, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=22.6351351351351, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=333, Percent_Identity=20.7207207207207, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322615, Length=212, Percent_Identity=23.5849056603774, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640980, Length=347, Percent_Identity=23.342939481268, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45549126, Length=347, Percent_Identity=23.342939481268, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42884; Mature: 42753

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRRFLKMAALTGAAMCVGPTLNKVTAAERVWMGKQQVANNIPAGMAAVRTRRTLGHGN
CCHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCC
TAFTVSAMGYGCMGLNHNRSQYPSREKEIALVHEAVERGVTLFDTAESYGYHINEKLVGE
CEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCCCCCHHHHHH
ALKGYTDRVFVSSKFGHKFVNGVQIKTEEDSTPANIRRVCENSLRNLGVETLGMFYQHRI
HHHCCCCEEEEECHHCHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DPNTPIEAVAETCSKLIKEGKILHWGMCEVNVDTIRRAHKICPVTAIQSEYHLMHRMVET
CCCCCHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NGVLELCEDLGIGFVPYSPLNRGFLGGMINEYTKFDVTNDNRQTLPRFQPEAIRANYRIV
CCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCHHCCCCCCCHHHHCCHHHH
EVLNAFGRTRGITPAQIALAWLMNKKPFIVPIPGTTKLSHLEENLRACDIRFTAEEIEEL
HHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHEEEEECHHHHHHH
ETAVAAIPVVGSRYDALQESKIPK
HHHHHHHCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
SRRRFLKMAALTGAAMCVGPTLNKVTAAERVWMGKQQVANNIPAGMAAVRTRRTLGHGN
CHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCC
TAFTVSAMGYGCMGLNHNRSQYPSREKEIALVHEAVERGVTLFDTAESYGYHINEKLVGE
CEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCCCCCHHHHHH
ALKGYTDRVFVSSKFGHKFVNGVQIKTEEDSTPANIRRVCENSLRNLGVETLGMFYQHRI
HHHCCCCEEEEECHHCHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DPNTPIEAVAETCSKLIKEGKILHWGMCEVNVDTIRRAHKICPVTAIQSEYHLMHRMVET
CCCCCHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NGVLELCEDLGIGFVPYSPLNRGFLGGMINEYTKFDVTNDNRQTLPRFQPEAIRANYRIV
CCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCHHCCCCCCCHHHHCCHHHH
EVLNAFGRTRGITPAQIALAWLMNKKPFIVPIPGTTKLSHLEENLRACDIRFTAEEIEEL
HHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHEEEEECHHHHHHH
ETAVAAIPVVGSRYDALQESKIPK
HHHHHHHCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]