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The map label for this gene is vexA

Identifier: 29144599

GI number: 29144599

Start: 4499011

End: 4500078

Strand: Reverse

Name: vexA

Synonym: t4348

Alternate gene names: 29144599

Gene position: 4500078-4499011 (Counterclockwise)

Preceding gene: 29144600

Following gene: 29144598

Centisome position: 93.91

GC content: 48.22

Gene sequence:

>1068_bases
ATGAAAAAAATCATCATATTACTAACGACATTTTTCCTGCTTTCGGGATGCACTATTCCCAGGGCGGTATTTAAATCCAG
CCTTATTAATCAGGACGATCCTCGTTATAATCTGGTCGAAGTCACGCCGACATTAAAACTAAGCGCTCCCGATACTGTGC
CGAAAACTATTGTCGATCCGGTTTTTGCCGCAAATAACTGGCACTGGACATCTTTGGCTAAAGGCGATGTGCTGCATATC
ACTATTTTATCCTCGGGCGGGGCTGGATATTTATCCAATAACGCGAGCGGCGACCGTGCGGATTTTGAAAATATTCTTGT
GACTGACAGTAATACCGTTCAGGTGCCTTATGCCGGGACAATCCCGGTTTCTGGATTGGATGTGACGCAACTGGCTGATG
AGATCAAAAAGCGACTTTCGCGCGTTGTCCTGAATCCTCAGGTGATTGTGACACTTACCGCCCGCACCGGAGCCATGGTG
ACGGTCGAGGGCAGCGGGAAAACGGGTCGATACCCTCTCGAACAGAGTATGAATCGTCTGAGTCATCTTTTGGCAACGGC
AGTGGCAGTAGAAAATACCAGCACAGATATGATGGAAGTTCACGTGACGCGCCAGCAGCATTATTTCACTGCGCGACTGT
CAGATATTTATCAGTATCCCGGATTGGATATTGCCTTACAGCCGGATGACCGTATCACTCTGCGTCAAGTGACCGAGTAT
GTTAATGTGCTCGGCGCAGCAGGTGTTCAGGGGAAACATGCTCTGGTTCAGCGTCATTCCAGCGTCGTGGATGCTTTGGC
GCTCGCGAAAGGATTAAATGACAATCTTGCCGATCCGCAAGCGATTTTTCTGTACAAGCATAACGAAGCGGAACAGGCGA
AACAGCAGATGCGTAAGCTGAATATCTATCATGTCGATATGAGCCAACCTAACTCGGTGTTTTTAGCGCAGGCCATACGA
GTGGACAACGGCGATGTTATCTATATCTCGAACGCCTCTTTGACTGATTTCGCTAAGGTGAAAGCCGCATTCGATAGCTT
TTTGACCCGCGGCACTAATTCTTTCTAA

Upstream 100 bases:

>100_bases
CCGTGGAACATATGGTGGGAACGTTTGTAAAAACCATTGCCTCTCAGCCTCGTTAATTAATGGGCATCATTTTTCAGCTA
TTTCATTTATAAAATAAGTT

Downstream 100 bases:

>100_bases
TGTCGCCATATGAATATTTTGAAAAATAATTCTTATTATTTTATGAAACTCATTACCGTCTGTGAGTTAATTATTTTATT
GATGTCACGCGATATCAAAA

Product: VI polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKKIIILLTTFFLLSGCTIPRAVFKSSLINQDDPRYNLVEVTPTLKLSAPDTVPKTIVDPVFAANNWHWTSLAKGDVLHI
TILSSGGAGYLSNNASGDRADFENILVTDSNTVQVPYAGTIPVSGLDVTQLADEIKKRLSRVVLNPQVIVTLTARTGAMV
TVEGSGKTGRYPLEQSMNRLSHLLATAVAVENTSTDMMEVHVTRQQHYFTARLSDIYQYPGLDIALQPDDRITLRQVTEY
VNVLGAAGVQGKHALVQRHSSVVDALALAKGLNDNLADPQAIFLYKHNEAEQAKQQMRKLNIYHVDMSQPNSVFLAQAIR
VDNGDVIYISNASLTDFAKVKAAFDSFLTRGTNSF

Sequences:

>Translated_355_residues
MKKIIILLTTFFLLSGCTIPRAVFKSSLINQDDPRYNLVEVTPTLKLSAPDTVPKTIVDPVFAANNWHWTSLAKGDVLHI
TILSSGGAGYLSNNASGDRADFENILVTDSNTVQVPYAGTIPVSGLDVTQLADEIKKRLSRVVLNPQVIVTLTARTGAMV
TVEGSGKTGRYPLEQSMNRLSHLLATAVAVENTSTDMMEVHVTRQQHYFTARLSDIYQYPGLDIALQPDDRITLRQVTEY
VNVLGAAGVQGKHALVQRHSSVVDALALAKGLNDNLADPQAIFLYKHNEAEQAKQQMRKLNIYHVDMSQPNSVFLAQAIR
VDNGDVIYISNASLTDFAKVKAAFDSFLTRGTNSF
>Mature_355_residues
MKKIIILLTTFFLLSGCTIPRAVFKSSLINQDDPRYNLVEVTPTLKLSAPDTVPKTIVDPVFAANNWHWTSLAKGDVLHI
TILSSGGAGYLSNNASGDRADFENILVTDSNTVQVPYAGTIPVSGLDVTQLADEIKKRLSRVVLNPQVIVTLTARTGAMV
TVEGSGKTGRYPLEQSMNRLSHLLATAVAVENTSTDMMEVHVTRQQHYFTARLSDIYQYPGLDIALQPDDRITLRQVTEY
VNVLGAAGVQGKHALVQRHSSVVDALALAKGLNDNLADPQAIFLYKHNEAEQAKQQMRKLNIYHVDMSQPNSVFLAQAIR
VDNGDVIYISNASLTDFAKVKAAFDSFLTRGTNSF

Specific function: May form an ATP-driven capsule polysaccharide export apparatus, in association with the vexB, vexC and vexD proteins. May function as a membrane anchor for the polysaccharide. Possible porin properties

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family

Homologues:

Organism=Escherichia coli, GI1787218, Length=282, Percent_Identity=25.886524822695, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VEXA_SALTI (Q04976)

Other databases:

- EMBL:   D14156
- EMBL:   X67785
- EMBL:   AL627283
- EMBL:   AE014613
- PIR:   F36892
- RefSeq:   NP_458734.1
- RefSeq:   NP_807941.1
- ProteinModelPortal:   Q04976
- GeneID:   1068167
- GeneID:   1250856
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t4348
- KEGG:   sty:STY4655
- HOGENOM:   HBG675565
- OMA:   YVTEAPF
- ProtClustDB:   PRK15175
- BioCyc:   SENT209261:T4348-MONOMER
- BioCyc:   SENT220341:STY4655-MONOMER
- InterPro:   IPR003715

Pfam domain/function: PF02563 Poly_export

EC number: NA

Molecular weight: Translated: 38902; Mature: 38902

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIILLTTFFLLSGCTIPRAVFKSSLINQDDPRYNLVEVTPTLKLSAPDTVPKTIVDP
CCEEEEHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCCCHHHHCH
VFAANNWHWTSLAKGDVLHITILSSGGAGYLSNNASGDRADFENILVTDSNTVQVPYAGT
HHCCCCEEEEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCEEEEECCCEEEEECCCC
IPVSGLDVTQLADEIKKRLSRVVLNPQVIVTLTARTGAMVTVEGSGKTGRYPLEQSMNRL
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHH
SHLLATAVAVENTSTDMMEVHVTRQQHYFTARLSDIYQYPGLDIALQPDDRITLRQVTEY
HHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHH
VNVLGAAGVQGKHALVQRHSSVVDALALAKGLNDNLADPQAIFLYKHNEAEQAKQQMRKL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHC
NIYHVDMSQPNSVFLAQAIRVDNGDVIYISNASLTDFAKVKAAFDSFLTRGTNSF
EEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKIIILLTTFFLLSGCTIPRAVFKSSLINQDDPRYNLVEVTPTLKLSAPDTVPKTIVDP
CCEEEEHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCCCHHHHCH
VFAANNWHWTSLAKGDVLHITILSSGGAGYLSNNASGDRADFENILVTDSNTVQVPYAGT
HHCCCCEEEEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCEEEEECCCEEEEECCCC
IPVSGLDVTQLADEIKKRLSRVVLNPQVIVTLTARTGAMVTVEGSGKTGRYPLEQSMNRL
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHH
SHLLATAVAVENTSTDMMEVHVTRQQHYFTARLSDIYQYPGLDIALQPDDRITLRQVTEY
HHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHH
VNVLGAAGVQGKHALVQRHSSVVDALALAKGLNDNLADPQAIFLYKHNEAEQAKQQMRKL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHC
NIYHVDMSQPNSVFLAQAIRVDNGDVIYISNASLTDFAKVKAAFDSFLTRGTNSF
EEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8331073; 8248629; 11677608; 12644504