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The map label for this gene is dmsC [H]

Identifier: 29144474

GI number: 29144474

Start: 4384707

End: 4385480

Strand: Direct

Name: dmsC [H]

Synonym: t4214

Alternate gene names: 29144474

Gene position: 4384707-4385480 (Clockwise)

Preceding gene: 29144468

Following gene: 29144475

Centisome position: 91.5

GC content: 60.59

Gene sequence:

>774_bases
ATGCATGAGTTACCGCTGGTCTTTTTTACGGTCTTTACCCAGAGCGCGGTCGGCGCGTTTATTCTGCTGCTGATTGGCGG
CGCAATGGGGCTGGTCGCGCCGCGGCGTAAGGCTATCGGTCTGTTCTCGGTGATGTGCCTGTTTGGGATTGGCGTCGTTG
TCGGTACCTTCCACGTCGGGCAACCGTTGCGTGCGCTGAATATGCTGCTGCGCGTCGGACATTCGCCGATGAGTAACGAG
ATTGTCTTGTCGGCGGCTTTTGTGGCGCTCGGCGGTCTGGGGGCGCTCGGTTTATTGCTGAACCGTGCGACGCCGCTGTG
TAACGCGTTGGTCTGGTTGGCGGCGATAGTCGGGGTGGTCTTCTTATACGCCGTTCCGCAGATTTACCAACTGCCGACGG
TGGCGACCTGGCGTTCATCTTACACCACGGCAATGATGATATTGACGCCGTTGATTGGCGGCGGCGCGTTGGCGGCATTG
TTTGGCGTGCGCCGTCTGGGGCTACTGGTCAGCGTGTTGGCGATTTTGGTGAGCTTTTGTCTGCGCCCGGGCTATATGGC
GACGCTGATGAGCGCCGATAGCGCTCTGACCGCCGCGCAGCATAGCTGGTTTACCGCCCAGGCGGTATTGCTGGCGGCGG
GCGTGGTCGGGGTGGTGGTCTGCGCGCGCCTGAAATCGAGTGCTACGGTGCTGGCCATGACGGCTGTGGTGGTTATCGCG
GCGGAGTTGGCGGGTAGGATTGCGTTTTACAATCTGTGGACGCTGCCAATGTAG

Upstream 100 bases:

>100_bases
GCGTCGTTCACCCATCCTAACCTCATTATTAAACCGCATCCGAAAGCGAGACCCACGGGCGATACGGAAGGCGCAATCAT
GAACATTCGGGAGGTGCGCC

Downstream 100 bases:

>100_bases
TTTTTGCCCGGCTTGTGCCATGTAAGCCTGATAAGCGTAGCGTCATCAGGCGAAATATTTCAGGAGCTATTGCTATGCCT
TCCCGTGCTGTTTTGCCGCG

Product: dimethyl sulfoxide reductase subunit C

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MHELPLVFFTVFTQSAVGAFILLLIGGAMGLVAPRRKAIGLFSVMCLFGIGVVVGTFHVGQPLRALNMLLRVGHSPMSNE
IVLSAAFVALGGLGALGLLLNRATPLCNALVWLAAIVGVVFLYAVPQIYQLPTVATWRSSYTTAMMILTPLIGGGALAAL
FGVRRLGLLVSVLAILVSFCLRPGYMATLMSADSALTAAQHSWFTAQAVLLAAGVVGVVVCARLKSSATVLAMTAVVVIA
AELAGRIAFYNLWTLPM

Sequences:

>Translated_257_residues
MHELPLVFFTVFTQSAVGAFILLLIGGAMGLVAPRRKAIGLFSVMCLFGIGVVVGTFHVGQPLRALNMLLRVGHSPMSNE
IVLSAAFVALGGLGALGLLLNRATPLCNALVWLAAIVGVVFLYAVPQIYQLPTVATWRSSYTTAMMILTPLIGGGALAAL
FGVRRLGLLVSVLAILVSFCLRPGYMATLMSADSALTAAQHSWFTAQAVLLAAGVVGVVVCARLKSSATVLAMTAVVVIA
AELAGRIAFYNLWTLPM
>Mature_257_residues
MHELPLVFFTVFTQSAVGAFILLLIGGAMGLVAPRRKAIGLFSVMCLFGIGVVVGTFHVGQPLRALNMLLRVGHSPMSNE
IVLSAAFVALGGLGALGLLLNRATPLCNALVWLAAIVGVVFLYAVPQIYQLPTVATWRSSYTTAMMILTPLIGGGALAAL
FGVRRLGLLVSVLAILVSFCLRPGYMATLMSADSALTAAQHSWFTAQAVLLAAGVVGVVVCARLKSSATVLAMTAVVVIA
AELAGRIAFYNLWTLPM

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ynfH [H]

Homologues:

Organism=Escherichia coli, GI1787123, Length=281, Percent_Identity=32.0284697508897, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787873, Length=271, Percent_Identity=32.4723247232472, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 26886; Mature: 26886

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHEECCCC
>Mature Secondary Structure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HHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 8429002; 2170332 [H]