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The map label for this gene is adi [H]

Identifier: 29144465

GI number: 29144465

Start: 4368464

End: 4370734

Strand: Reverse

Name: adi [H]

Synonym: t4203

Alternate gene names: 29144465

Gene position: 4370734-4368464 (Counterclockwise)

Preceding gene: 29144466

Following gene: 29144464

Centisome position: 91.21

GC content: 54.16

Gene sequence:

>2271_bases
ATGATGAAAGTATTAATTGTTGAAAGTGAGTTTCTGCATCAGGACACCTGGGTTGGCAACGCGGTTGAGCGTCTGGCGGA
TGCCTTGAGCCAACAAAATGTTACCGTCATTAAATCGACATCCTTCGATGACGGCTATGCCATCTTGTCCGCGAACGAAG
CCATTGACTGTCTGATGTTTAGCTACCAAATGGAACAACCGGATGAGCACCTGAGCGTCAGGCAATTGATCGGTAAGCTT
CACGAGCGTCAGCAAAACGTGCCCGTTTTCCTGTTAGGCGACAGGGAAAAAGCGACGGCATCGCTGGACCGCGACCTGCT
GGAGCTTGTCGATGAATTCGCCTGGATTCTGGAAGACACCGCTGACTTTATCGCCGGACGCGCCGTTGCCGCCATGACCC
GGTATCGCCAGCAACTGTTACCGCCGCTGTTTAACGCGTTGATGAAATACAGCGACATTCATGAATATTCATGGGCGGCG
CCGGGACACCAGGGCGGCGTCGGTTTCACTAAAACGCCTGCCGGTCGCTTTTATCACGATTATTATGGCGAAAACCTGTT
CCGCAGCGATATGGGGATTGAGCGTACCACGCTCGGTTCACTCCTCGACCATACCGGCGCGTTTGGCGAAAGCGAGAAAA
ACGCCGCCCGCGTATTCGGTGCTGACCGCTCCTGGTCCGTGGTTGTCGGGACCTCAGGTTCTAACCGTACTATTATGCAG
GCCTGTATGACGGATAATGATGTCGTTGTACTGGATCGTAACTGCCATAAATCCATCGAACAGGGGCTGATCCTCACTGG
GGCCAAACCGGTATATATGGTGCCAAGCCGTAACCGTTACGGCATTATCGGGCCAATCTACCCGCAGGAAATGCAGCCTG
AAACCTTGCAGAAAAAAATCAGCGCCAGCCCGCTGACCAAAACCAAAGCCGGACAGAAACCGTCTTACAGCGTGGTGACC
AACTGTACCTATGACGGCGTATGCTATAACGCCAAAGAGGCGCAGGATCTGCTGGCAAAAACCAGCGATCGCATTCACTT
CGACGAAGCATGGTACGGCTATGCGCGCTTCAACCCGATTTATTGCGATCACTACGCGATGCGCGGCGAGCCAGGCGACC
ATAACGGTCCGACCGTGTTTGCCACCCACTCCACGCACAAATTACTGAACGCGCTTTCACAAGCTTCCTACATTCACGTC
CGTGAAGGCCGTGGCGCGGTGAATTTCTCCCGCTTCAACCAGGCCTATATGATGCATGCCACCACCTCTCCGTTATATGC
CATCTGCGCATCCAACGATGTGGCGGTATCGATGATGGACGGTAACAGCGGCCTGTCCCTGACTCAAGAGGTGATTGACG
AAGCGGTTGATTTCCGTCAGGCGATGGCGCGTCTTTATAAAGAGTTTACCGATGAAGGCGACTGGTTCTTTAAACCGTGG
AATAAAGACGTCGTCACCGATCCACAAACCGGTAAAACGTATGACTTCGCCGACGCGCCGGCAAAACTGCTGGCAACCGA
CCAGAACTGCTGGGTCATGCGCCCCGGGGAAACCTGGCACGGCTTTAAAGACCTGCCGGATAACTGGAGTATGCTGGACC
CGATTAAAGTCAGTATCCTGGCGCCGGGTATGGGCGACGATGGCGAACTGGAAGCATCCGGCGTACCTGCTGCGCTGGTC
ACAGCATGGCTTGGCCGCCACGGTATCGTGCCGACCCGCACCACCGACTTCCAGATTATGTTCCTGTTCTCCATGGGGGT
AACTCGCGGGAAATGGGGAACGCTGATCAACACGCTGTGCTCCTTCAAACATCATTACGACGCGAATACGCCGCTGGCGC
AGGTGATGCCGGAACTGGTGCAGGATTATCCTGACACTTACGCGAACATGGGTATTCATGACCTGGGCGATAAAATGTTT
GCCTGGCTACGTGAAAATAACCCGGGCGCCCGTCTCAATGCCGCCTATTCCACCCTGCCGGTTGCGGAGATTACCCCGCG
CGACGCCTACAACGCGATCGTGAACAACAATATTGAAATGGTGGCGATTGAAAATCTACCGGGTCGCATTGCGGCGAACT
CCGTTATTCCTTACCCGCCAGGCATCCCGATGCTGCTCTCCGGTGAAAACTTTGGCGATGAAAACAGTCCGCAGGTGGGT
TACTTACGCTCACTGCAATCCTGGGATCATCACTTCCCTGGCTTTGAGCATGAAACCGAAGGCACGGAAATTATTGATGG
CGTATATCACGTTATGTGCGTGAAAGCCTAA

Upstream 100 bases:

>100_bases
CTTTACACCCCCTATTTGACGGGGTAATACTTGCCCACGTCACATTCATACGGCGGGTCGGCAAGGCGTAAATTGCACGG
CCTCCACAACCGGGTAAAAG

Downstream 100 bases:

>100_bases
TCACAAAGAGTCTTTTTTTGAGGATGGCATGTATTCCCTGAGTATTGCTGCAAAACAATAATACTGTCATACCTTTTTGC
GCGGGCCCCATCCCGCGCTT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MMKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGYAILSANEAIDCLMFSYQMEQPDEHLSVRQLIGKL
HERQQNVPVFLLGDREKATASLDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFNALMKYSDIHEYSWAA
PGHQGGVGFTKTPAGRFYHDYYGENLFRSDMGIERTTLGSLLDHTGAFGESEKNAARVFGADRSWSVVVGTSGSNRTIMQ
ACMTDNDVVVLDRNCHKSIEQGLILTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISASPLTKTKAGQKPSYSVVT
NCTYDGVCYNAKEAQDLLAKTSDRIHFDEAWYGYARFNPIYCDHYAMRGEPGDHNGPTVFATHSTHKLLNALSQASYIHV
REGRGAVNFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTDEGDWFFKPW
NKDVVTDPQTGKTYDFADAPAKLLATDQNCWVMRPGETWHGFKDLPDNWSMLDPIKVSILAPGMGDDGELEASGVPAALV
TAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLINTLCSFKHHYDANTPLAQVMPELVQDYPDTYANMGIHDLGDKMF
AWLRENNPGARLNAAYSTLPVAEITPRDAYNAIVNNNIEMVAIENLPGRIAANSVIPYPPGIPMLLSGENFGDENSPQVG
YLRSLQSWDHHFPGFEHETEGTEIIDGVYHVMCVKA

Sequences:

>Translated_756_residues
MMKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGYAILSANEAIDCLMFSYQMEQPDEHLSVRQLIGKL
HERQQNVPVFLLGDREKATASLDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFNALMKYSDIHEYSWAA
PGHQGGVGFTKTPAGRFYHDYYGENLFRSDMGIERTTLGSLLDHTGAFGESEKNAARVFGADRSWSVVVGTSGSNRTIMQ
ACMTDNDVVVLDRNCHKSIEQGLILTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISASPLTKTKAGQKPSYSVVT
NCTYDGVCYNAKEAQDLLAKTSDRIHFDEAWYGYARFNPIYCDHYAMRGEPGDHNGPTVFATHSTHKLLNALSQASYIHV
REGRGAVNFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTDEGDWFFKPW
NKDVVTDPQTGKTYDFADAPAKLLATDQNCWVMRPGETWHGFKDLPDNWSMLDPIKVSILAPGMGDDGELEASGVPAALV
TAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLINTLCSFKHHYDANTPLAQVMPELVQDYPDTYANMGIHDLGDKMF
AWLRENNPGARLNAAYSTLPVAEITPRDAYNAIVNNNIEMVAIENLPGRIAANSVIPYPPGIPMLLSGENFGDENSPQVG
YLRSLQSWDHHFPGFEHETEGTEIIDGVYHVMCVKA
>Mature_756_residues
MMKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGYAILSANEAIDCLMFSYQMEQPDEHLSVRQLIGKL
HERQQNVPVFLLGDREKATASLDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFNALMKYSDIHEYSWAA
PGHQGGVGFTKTPAGRFYHDYYGENLFRSDMGIERTTLGSLLDHTGAFGESEKNAARVFGADRSWSVVVGTSGSNRTIMQ
ACMTDNDVVVLDRNCHKSIEQGLILTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISASPLTKTKAGQKPSYSVVT
NCTYDGVCYNAKEAQDLLAKTSDRIHFDEAWYGYARFNPIYCDHYAMRGEPGDHNGPTVFATHSTHKLLNALSQASYIHV
REGRGAVNFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTDEGDWFFKPW
NKDVVTDPQTGKTYDFADAPAKLLATDQNCWVMRPGETWHGFKDLPDNWSMLDPIKVSILAPGMGDDGELEASGVPAALV
TAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLINTLCSFKHHYDANTPLAQVMPELVQDYPDTYANMGIHDLGDKMF
AWLRENNPGARLNAAYSTLPVAEITPRDAYNAIVNNNIEMVAIENLPGRIAANSVIPYPPGIPMLLSGENFGDENSPQVG
YLRSLQSWDHHFPGFEHETEGTEIIDGVYHVMCVKA

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=755, Percent_Identity=93.112582781457, Blast_Score=1501, Evalue=0.0,
Organism=Escherichia coli, GI1790573, Length=740, Percent_Identity=35.4054054054054, Blast_Score=467, Evalue=1e-132,
Organism=Escherichia coli, GI1786384, Length=737, Percent_Identity=34.8710990502035, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI87082193, Length=622, Percent_Identity=33.7620578778135, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1786909, Length=681, Percent_Identity=30.6901615271659, Blast_Score=333, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 84306; Mature: 84306

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGYAILSANEAIDCLMF
CEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCHHHHHHH
SYQMEQPDEHLSVRQLIGKLHERQQNVPVFLLGDREKATASLDRDLLELVDEFAWILEDT
HHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADFIAGRAVAAMTRYRQQLLPPLFNALMKYSDIHEYSWAAPGHQGGVGFTKTPAGRFYHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
YYGENLFRSDMGIERTTLGSLLDHTGAFGESEKNAARVFGADRSWSVVVGTSGSNRTIMQ
HHCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHEECCCCCEEEEEECCCCCCHHHH
ACMTDNDVVVLDRNCHKSIEQGLILTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKI
HHCCCCCEEEECCCHHHHHHCCEEEECCCCEEECCCCCCCEEECCCCCCCCCHHHHHHHH
SASPLTKTKAGQKPSYSVVTNCTYDGVCYNAKEAQDLLAKTSDRIHFDEAWYGYARFNPI
CCCCCCCCCCCCCCCCEEEECCEECCEEECHHHHHHHHHHCCCCEEECCCEECEEECCCE
YCDHYAMRGEPGDHNGPTVFATHSTHKLLNALSQASYIHVREGRGAVNFSRFNQAYMMHA
EECCEEECCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEECCCCCEEHHHHCCEEEEEE
TTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTDEGDWFFKPW
CCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
NKDVVTDPQTGKTYDFADAPAKLLATDQNCWVMRPGETWHGFKDLPDNWSMLDPIKVSIL
CCCCCCCCCCCCCCCCCCCCHHHEECCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEE
APGMGDDGELEASGVPAALVTAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLINTLC
ECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH
SFKHHYDANTPLAQVMPELVQDYPDTYANMGIHDLGDKMFAWLRENNPGARLNAAYSTLP
HHHHCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEHHHHCC
VAEITPRDAYNAIVNNNIEMVAIENLPGRIAANSVIPYPPGIPMLLSGENFGDENSPQVG
CHHCCCCHHHHHHHCCCEEEEEEECCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCHH
YLRSLQSWDHHFPGFEHETEGTEIIDGVYHVMCVKA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECC
>Mature Secondary Structure
MMKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGYAILSANEAIDCLMF
CEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCHHHHHHH
SYQMEQPDEHLSVRQLIGKLHERQQNVPVFLLGDREKATASLDRDLLELVDEFAWILEDT
HHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADFIAGRAVAAMTRYRQQLLPPLFNALMKYSDIHEYSWAAPGHQGGVGFTKTPAGRFYHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
YYGENLFRSDMGIERTTLGSLLDHTGAFGESEKNAARVFGADRSWSVVVGTSGSNRTIMQ
HHCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHEECCCCCEEEEEECCCCCCHHHH
ACMTDNDVVVLDRNCHKSIEQGLILTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKI
HHCCCCCEEEECCCHHHHHHCCEEEECCCCEEECCCCCCCEEECCCCCCCCCHHHHHHHH
SASPLTKTKAGQKPSYSVVTNCTYDGVCYNAKEAQDLLAKTSDRIHFDEAWYGYARFNPI
CCCCCCCCCCCCCCCCEEEECCEECCEEECHHHHHHHHHHCCCCEEECCCEECEEECCCE
YCDHYAMRGEPGDHNGPTVFATHSTHKLLNALSQASYIHVREGRGAVNFSRFNQAYMMHA
EECCEEECCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEECCCCCEEHHHHCCEEEEEE
TTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTDEGDWFFKPW
CCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
NKDVVTDPQTGKTYDFADAPAKLLATDQNCWVMRPGETWHGFKDLPDNWSMLDPIKVSIL
CCCCCCCCCCCCCCCCCCCCHHHEECCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEE
APGMGDDGELEASGVPAALVTAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLINTLC
ECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH
SFKHHYDANTPLAQVMPELVQDYPDTYANMGIHDLGDKMFAWLRENNPGARLNAAYSTLP
HHHHCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEHHHHCC
VAEITPRDAYNAIVNNNIEMVAIENLPGRIAANSVIPYPPGIPMLLSGENFGDENSPQVG
CHHCCCCHHHHHHHCCCEEEEEEECCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCHH
YLRSLQSWDHHFPGFEHETEGTEIIDGVYHVMCVKA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]