Click here to switch to the map view.

The map label for this gene is ywbI [H]

Identifier: 29144438

GI number: 29144438

Start: 4339161

End: 4340048

Strand: Reverse

Name: ywbI [H]

Synonym: t4176

Alternate gene names: 29144438

Gene position: 4340048-4339161 (Counterclockwise)

Preceding gene: 29144441

Following gene: 29144433

Centisome position: 90.57

GC content: 55.86

Gene sequence:

>888_bases
ATGGATATCAGAACGCTGCGTTATTTTGTCGAGGTGGTGCGCCAGCAAAGTTTCACCCGCGCAGCGGAGAAGTTATTTGT
CACCCAGCCCACCATTAGCAAGATGCTGAAAAATCTTGAAGATGAGCTTAACTGTACGCTACTGATCCGCGACGGACGTA
AGTTATTGCTGACCGATACCGGACGCGTGGTGTTTGAACGCGGTCTGGCGATCCTCGCTGAGTTTCGCCAGTTAGAGGCC
GAGTTGAGCGATATTAACCATCTCAATAAGGGCGTGCTGCGGCTGGGTATTCCCCCGATGGTCGGCATGTTGATGGCTGG
GCCAATCAGTTTGTTTCGACAACGCTACCCTGGCGTTGAACTCAAAATTTCGGAGTTTGGCGGCCTGACGGTACAGCAGG
CGGTAATGAATGGCGAGCTGGATGTTGCGATGACCGCGCTCCCGGTGGAAGAAGCGAGCGGGCTGACGACATTATCGCTG
TTCAGCCATCCGCTGTGCGTGCTGGTTCCCCGTTCCGGTCAGTGGACAACCTGCGACTCCATCGCGCCTGAAGCTCTGGC
GGAGCATCCTCTTCTTATCTATAACGAAGACTTTGCCCTGAGCCGCCAGTTGATGACCTTATTTAGCCAGCATGACGTAA
AACCACGGATTGCCGTGCGCAGCGGGCAATGGGATTTTCTCGCCGCCATGGTGCAAGCGGGCGTCGGCATCGCCATTTTG
CCGGAGCCGATTTGTCAGCGTCTGGATAAGGCCACGCTGCGCTGGCTACCGCTGGAAAGTGATCTCCGCTGGCAGTTGGG
CATGATTTGGCGCGAGGGCGTGTATCTGTCGCACAGCGCCCGGGCATGGTTAACCTGTTGCGAAGGGTTTTGGCTGAAAC
AACCGTAA

Upstream 100 bases:

>100_bases
GGAATGTCCTGAAAAATAATACGGAGCGCCAGTATAGAGAACCTCCGTCACGGGCAGAAATGAATTAAAATCATTGCAGG
CATAGTCGGAAGGAATAATC

Downstream 100 bases:

>100_bases
GCCATGGGTTAAAACCCTTGCCGGATGGCGGCGCAAGCACCTTACCGGGCCTACTTGTAGGCCCGATAAGCATGGCGCCA
CCGGGCCACAAGGACTACTG

Product: lysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDTGRVVFERGLAILAEFRQLEA
ELSDINHLNKGVLRLGIPPMVGMLMAGPISLFRQRYPGVELKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSL
FSHPLCVLVPRSGQWTTCDSIAPEALAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIAVRSGQWDFLAAMVQAGVGIAIL
PEPICQRLDKATLRWLPLESDLRWQLGMIWREGVYLSHSARAWLTCCEGFWLKQP

Sequences:

>Translated_295_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDTGRVVFERGLAILAEFRQLEA
ELSDINHLNKGVLRLGIPPMVGMLMAGPISLFRQRYPGVELKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSL
FSHPLCVLVPRSGQWTTCDSIAPEALAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIAVRSGQWDFLAAMVQAGVGIAIL
PEPICQRLDKATLRWLPLESDLRWQLGMIWREGVYLSHSARAWLTCCEGFWLKQP
>Mature_295_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDTGRVVFERGLAILAEFRQLEA
ELSDINHLNKGVLRLGIPPMVGMLMAGPISLFRQRYPGVELKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSL
FSHPLCVLVPRSGQWTTCDSIAPEALAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIAVRSGQWDFLAAMVQAGVGIAIL
PEPICQRLDKATLRWLPLESDLRWQLGMIWREGVYLSHSARAWLTCCEGFWLKQP

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=28.7769784172662, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=26.8041237113402, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=25.9109311740891, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788297, Length=263, Percent_Identity=26.615969581749, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788887, Length=276, Percent_Identity=25.7246376811594, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787530, Length=243, Percent_Identity=25.9259259259259, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI2367136, Length=262, Percent_Identity=25.5725190839695, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI145693105, Length=302, Percent_Identity=23.5099337748344, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789506, Length=278, Percent_Identity=21.5827338129496, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786401, Length=251, Percent_Identity=30.6772908366534, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788481, Length=292, Percent_Identity=24.3150684931507, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789173, Length=195, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=24.7967479674797, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=30.1369863013699, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788748, Length=289, Percent_Identity=25.2595155709343, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=263, Percent_Identity=22.4334600760456, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789639, Length=194, Percent_Identity=28.3505154639175, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787806, Length=277, Percent_Identity=21.6606498194946, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI145693193, Length=126, Percent_Identity=30.1587301587302, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33248; Mature: 33248

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEECC
GRVVFERGLAILAEFRQLEAELSDINHLNKGVLRLGIPPMVGMLMAGPISLFRQRYPGVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHCCCCE
LKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSLFSHPLCVLVPRSGQWTTCDS
EEECCCCCCHHHHHHHCCCCCEEEEEECHHHHCCCEEEHHHCCCEEEEEECCCCCCCHHC
IAPEALAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIAVRSGQWDFLAAMVQAGVGIAIL
CCHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEC
PEPICQRLDKATLRWLPLESDLRWQLGMIWREGVYLSHSARAWLTCCEGFWLKQP
CHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCEEEECCHHHHHHHHCCCEECCC
>Mature Secondary Structure
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEECC
GRVVFERGLAILAEFRQLEAELSDINHLNKGVLRLGIPPMVGMLMAGPISLFRQRYPGVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHCCCCE
LKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSLFSHPLCVLVPRSGQWTTCDS
EEECCCCCCHHHHHHHCCCCCEEEEEECHHHHCCCEEEHHHCCCEEEEEECCCCCCCHHC
IAPEALAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIAVRSGQWDFLAAMVQAGVGIAIL
CCHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEC
PEPICQRLDKATLRWLPLESDLRWQLGMIWREGVYLSHSARAWLTCCEGFWLKQP
CHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCEEEECCHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]