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The map label for this gene is actP [H]

Identifier: 29144441

GI number: 29144441

Start: 4341283

End: 4342932

Strand: Reverse

Name: actP [H]

Synonym: t4179

Alternate gene names: 29144441

Gene position: 4342932-4341283 (Counterclockwise)

Preceding gene: 29144442

Following gene: 29144438

Centisome position: 90.63

GC content: 55.94

Gene sequence:

>1650_bases
ATGAAGAGAGTTCTGACGGCGCTCGCCGCCGCACTCCCCTTCGCCGCTCATGCGGCGGATGCCATTAGCGGCGCGGTTGA
ACGCCAGCCCACCAACTGGCAGGCGATTATCATGTTTTTGATTTTCGTCGTGTTTACGCTCGGTATTACCTACTGGGCCT
CTAAACGCGTACGTTCCCGTAGCGACTACTACACGGCTGGCGGCAATATCACCGGGTTCCAGAACGGGCTGGCGATTGCC
GGCGACTATATGTCCGCCGCGTCATTTCTCGGCATTTCCGCGCTGGTGTTTACCTCCGGTTATGACGGGCTGATCTATTC
GCTGGGCTTCCTTGTCGGCTGGCCAATTATCCTGTTTTTGATTGCCGAGCGCCTGCGTAATCTGGGACGTTATACTTTTG
CTGACGTTGCCTCTTATCGCCTGAAACAGGGGCCAATCCGTATTCTTTCGGCCTGTGGCTCCCTGGTAGTGGTGGCGCTT
TATCTCATCGCCCAAATGGTCGGCGCCGGTAAACTGATTGAACTGCTGTTCGGCCTCAACTATCACATCGCCGTAGTGCT
GGTCGGCGTGCTGATGATGATGTACGTGCTGTTCGGCGGGATGCTGGCGACAACGTGGGTGCAAATTATCAAAGCCGTCC
TGTTGCTGTTTGGCGCCAGTTTTATGGCCTTTATGGTGATGAAACACGTCGGCTTTAGCTTCAATAATCTGTTTACCGAA
GCCATGGCGGTACACCCGAAAGGCACGGCGATTATGAGCCCAGGAGGATTGGTGCAAGATCCGATTTCGGCATTGTCGTT
GGGTCTGGGACTGATATTCGGCACCGCCGGTTTGCCGCATATTCTGATGCGTTTCTTTACGGTCAGCGATGCCCGCGAAG
CGCGCAAGAGCGTGTTCTACGCCACCGGTTTTATGGGCTATTTCTACATTCTGACCTTTATTATCGGCTTCGGCGCTATC
ATGCTGGTGGGGGCGAATCCCGCCTATAAAGATGCCGCAGGCGCGCTGATTGGCGGCAATAACATGGCGGCGGTGCATCT
GGCCAACGCGGTAGGCGGCAACCTGTTCCTCGGCTTTATTTCGGCAGTGGCGTTTGCCACCATTCTGGCGGTGGTCGCAG
GTCTGACGCTGGCGGGCGCATCGGCGGTGTCGCATGACTTGTACGCCAACGTGTTCCGCAAAGGCGCAACCGAACGTGAA
GAGCTGAAGGTGTCGAAAATCACCGTCCTGGTGCTGGACGTGATCGCCATTATCCTCGGCGTCCTGTTTGAAAATCAGAA
CATCGCCTTTATGGTGGGCCTGGCATTTGCTATCGCCGCGAGCTGCAACTTCCCCATCATTCTGCTTTCCATGTACTGGT
CAAAACTGACCACGCGCGGCGCTATGCTGGGCGGCTGGTTAGGTTTACTGACAGCGGTGGTGCTGATGATTCTTGGCCCT
ACCATTTGGGTGCAGATCCTCGGCCACGAAAAAGCGATCTTCCCGTATGAGTATCCGGCGCTGTTCTCTATCAGCGTGGC
GTTCCTGGGGATCTGGTTCTTCTCGGCCACCGATAACTCGGCAGAAGGCAACCGTGAACGTGAGCAGTTCCGCGCTCAGT
TTATCCGCTCCCAAACGGGATTCGGCGTACAACAAGGGCGTGCGCATTAA

Upstream 100 bases:

>100_bases
TGATTGTGATTTCTTTTGTGTTGACCGGAATTTATATCTGGCGGGCGAATGGCGAATTCGATCGTCTTAATAACGCCGTA
CTGCATGAGGTGAAAGCATT

Downstream 100 bases:

>100_bases
TCTTACCGTTTCCTCCGGCCCTGTGGGTCGGAGGAAAATCAGAACATCACCCTCGCCACCAGCGGGGCTGCCAGCACCAT
CACCACGCCGGACAGCATCA

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTE
AMAVHPKGTAIMSPGGLVQDPISALSLGLGLIFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPAYKDAAGALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATERE
ELKVSKITVLVLDVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH

Sequences:

>Translated_549_residues
MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTE
AMAVHPKGTAIMSPGGLVQDPISALSLGLGLIFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPAYKDAAGALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATERE
ELKVSKITVLVLDVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH
>Mature_549_residues
MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTE
AMAVHPKGTAIMSPGGLVQDPISALSLGLGLIFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPAYKDAAGALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATERE
ELKVSKITVLVLDVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=470, Percent_Identity=26.1702127659574, Blast_Score=115, Evalue=8e-26,
Organism=Escherichia coli, GI1790503, Length=549, Percent_Identity=96.3570127504554, Blast_Score=1056, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=451, Percent_Identity=27.2727272727273, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59049; Mature: 59049

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCC
>Mature Secondary Structure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CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA