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The map label for this gene is glpR [H]

Identifier: 29144258

GI number: 29144258

Start: 4134786

End: 4135544

Strand: Direct

Name: glpR [H]

Synonym: t3990

Alternate gene names: 29144258

Gene position: 4134786-4135544 (Clockwise)

Preceding gene: 29144257

Following gene: 29144260

Centisome position: 86.29

GC content: 53.62

Gene sequence:

>759_bases
ATGAAACAAACACAACGGCATGACGCGATCATTGAACTGGTGAAAAAACAGGGGTACGTCAGTACGGAAGAGCTGGTGGA
GCATTTTTCTGTCAGCCCGCAAACCATTCGTCGGGATCTTAACGATCTGGCGGAACAGAATATGATTTTGCGCCACCACG
GCGGCGCGGCGTTGCCCTCCAGCTCGGTGAACACGCCGTGGCACGATCGTAAGGCGACGCAAACGGAAGAAAAAGAGCGC
ATCGCTCGCAAAGTCGCGGCCCAGATCCCCAATGGTTCAACGCTGTTTATTGATATCGGCACGACGCCGGAAGCCGTAGC
GCACACCCTGTTAGGGCACAGTAATTTGCGGATCGTGACCAACAATTTGAACGTAGCGAACACGCTAATGGCGAAAGAGG
ATTTTCGTATTATCCTCGCCGGCGGCGAACTCCGTAGCCGCGACGGCGGCATTATTGGCGAAGCGACGCAGGACTTTATC
GCCCAGTTCCGTCTCGATTTCGGCATTCTCGGTATTAGCGGTATTGATAGCGACGGCTCATTGCTGGAATTTGACTACCA
TGAGGTACGCACCAAGCGCGCGATTATCGAAAATTCGCGCCACGTGATGCTGGTGGTGGATCACTCTAAATTTGGCCGTA
ACGCGATGGTAAACATGGGCAGCATTAGTATGGTCGATGCGGTCTACACCGATACCCTACCACCGCCGGGCGTGATGCAG
GTGATTGCCGACCACCATATTCAATTAGAGCTGTGCTAA

Upstream 100 bases:

>100_bases
GAACGTGAGGCGTATCCGGCCTGTGGTCGAGATATTTTTCCAGGCCGGGTAGGGCGATGCCGCTATCCGGCGCAAGGTTG
GTTACTTTCAGAGATTATTC

Downstream 100 bases:

>100_bases
AAAGACTGTCTTATCAGGCCTACACTCTGCGCGCGATGGTAGGCCTGATAAGCGAAGCGCCATCAGGCACACGTTAAACC
CCATACCCCATCATCTTCAG

Product: DNA-binding transcriptional repressor GlpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKQTQRHDAIIELVKKQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNMILRHHGGAALPSSSVNTPWHDRKATQTEEKER
IARKVAAQIPNGSTLFIDIGTTPEAVAHTLLGHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATQDFI
AQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDTLPPPGVMQ
VIADHHIQLELC

Sequences:

>Translated_252_residues
MKQTQRHDAIIELVKKQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNMILRHHGGAALPSSSVNTPWHDRKATQTEEKER
IARKVAAQIPNGSTLFIDIGTTPEAVAHTLLGHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATQDFI
AQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDTLPPPGVMQ
VIADHHIQLELC
>Mature_252_residues
MKQTQRHDAIIELVKKQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNMILRHHGGAALPSSSVNTPWHDRKATQTEEKER
IARKVAAQIPNGSTLFIDIGTTPEAVAHTLLGHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATQDFI
AQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDTLPPPGVMQ
VIADHHIQLELC

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=93.2539682539683, Blast_Score=486, Evalue=1e-139,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=44.3089430894309, Blast_Score=227, Evalue=5e-61,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=29.8804780876494, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=30.2788844621514, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1789519, Length=240, Percent_Identity=27.9166666666667, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI226510968, Length=250, Percent_Identity=29.6, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=29.2576419213974, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787063, Length=250, Percent_Identity=26, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790635, Length=245, Percent_Identity=24.8979591836735, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787540, Length=229, Percent_Identity=28.3842794759825, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790753, Length=253, Percent_Identity=24.5059288537549, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27937; Mature: 27937

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTQRHDAIIELVKKQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNMILRHHGGAALPS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCC
SSVNTPWHDRKATQTEEKERIARKVAAQIPNGSTLFIDIGTTPEAVAHTLLGHSNLRIVT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATQDFIAQFRLDFGILGISGIDSDGS
CCCCHHHHHHCCCCCEEEEECCCEECCCCCEECHHHHHHHHHHHHHHEEEEEECCCCCCC
LLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDTLPPPGVMQ
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCCHHHHHHHHHCCCCCCHHHH
VIADHHIQLELC
HHHCCCEEEEEC
>Mature Secondary Structure
MKQTQRHDAIIELVKKQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNMILRHHGGAALPS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCC
SSVNTPWHDRKATQTEEKERIARKVAAQIPNGSTLFIDIGTTPEAVAHTLLGHSNLRIVT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATQDFIAQFRLDFGILGISGIDSDGS
CCCCHHHHHHCCCCCEEEEECCCEECCCCCEECHHHHHHHHHHHHHHEEEEEECCCCCCC
LLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDTLPPPGVMQ
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCCHHHHHHHHHCCCCCCHHHH
VIADHHIQLELC
HHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]