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The map label for this gene is glpG [H]

Identifier: 29144257

GI number: 29144257

Start: 4133863

End: 4134693

Strand: Direct

Name: glpG [H]

Synonym: t3989

Alternate gene names: 29144257

Gene position: 4133863-4134693 (Clockwise)

Preceding gene: 29144256

Following gene: 29144258

Centisome position: 86.27

GC content: 54.51

Gene sequence:

>831_bases
ATGTTGATGATTACTTCCTTTGCGAATCCTCGCGTGGCGCAGGCATTTGTTGATTACATGGCCACCCAGGGCGTCATTCT
TACTATTCAGCAACATAATCAAAGCGATATCTGGCTGGCGGATGAATCGCAGGCCGAACGTGTGCGGGTCGAGCTGGCGC
GGTTTATAGAAAATCCCGGCGATCCGCGTTATCTGGCGGCTAGCTGGCAGTCCGGGCAGACTAACAGCGGGCTACGCTAC
CGCCGTTTTCCCTTTCTCGCCACGCTGCGTGAACGAGCCGGCCCTGTTACCTGGATCGTGATGCTCGCCTGCGTGGTGGT
CTATATCGCGATGAGTCTCATCGGCGATCAGACGGTGATGGTGTGGCTGGCGTGGCCGTTCGATCCGGTTTTAAAATTTG
AAGTCTGGCGCTACTTCACCCATATCTTTATGCACTTCTCACTGATGCATATTCTTTTTAACCTGCTGTGGTGGTGGTAT
CTCGGCGGGGCGGTAGAGAAGCGCCTGGGCAGCGGTAAATTAATCGTCATTACGGTGATAAGCGCGCTGCTAAGCGGCTA
TGTACAGCAGAAATTTAGCGGCCCGTGGTTTGGCGGGCTGTCCGGCGTCGTCTATGCGCTGATGGGGTACGTGTGGCTGC
GCGGAGAGCGCGATCCGCAAAGCGGAATTTACCTCCAGCGCGGCTTAATTATTTTTGCATTATTGTGGATAGTTGCTGGT
TGGTTTGACTGGTTTGGCATGTCTATGGCGAACGGCGCGCACATCGCCGGGCTTATCGTCGGTTTAGCGATGGCCTTTGT
TGATACGCTGAATGCGCGAAAACGAACGTGA

Upstream 100 bases:

>100_bases
TGCCGATGTCGCGAATGGCGCGTAATCCCATAAAGATGCAGCCTCCGACGAGAAGGGTATATATACTGTCTTCTTTTGTA
TGGACTAAGCGACAGCAATA

Downstream 100 bases:

>100_bases
GGCGTATCCGGCCTGTGGTCGAGATATTTTTCCAGGCCGGGTAGGGCGATGCCGCTATCCGGCGCAAGGTTGGTTACTTT
CAGAGATTATTCATGAAACA

Product: intramembrane serine protease GlpG

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRVELARFIENPGDPRYLAASWQSGQTNSGLRY
RRFPFLATLRERAGPVTWIVMLACVVVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWY
LGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAG
WFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT

Sequences:

>Translated_276_residues
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRVELARFIENPGDPRYLAASWQSGQTNSGLRY
RRFPFLATLRERAGPVTWIVMLACVVVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWY
LGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAG
WFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
>Mature_276_residues
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRVELARFIENPGDPRYLAASWQSGQTNSGLRY
RRFPFLATLRERAGPVTWIVMLACVVVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWY
LGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAG
WFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=276, Percent_Identity=89.1304347826087, Blast_Score=514, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 31427; Mature: 31427

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRVELARFIENPG
CEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCC
DPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVVVYIAMSLIGDQTVM
CCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEE
VWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
WFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRVELARFIENPG
CEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCC
DPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVVVYIAMSLIGDQTVM
CCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEE
VWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
WFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA