| Definition | Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome. |
|---|---|
| Accession | NC_004631 |
| Length | 4,791,961 |
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The map label for this gene is selA
Identifier: 29144115
GI number: 29144115
Start: 3959511
End: 3960902
Strand: Direct
Name: selA
Synonym: t3836
Alternate gene names: 29144115
Gene position: 3959511-3960902 (Clockwise)
Preceding gene: 29144114
Following gene: 29144116
Centisome position: 82.63
GC content: 59.34
Gene sequence:
>1392_bases ATGACAAGCGAAACGCGTACACTCTACAGCCAGCTTCCTGCTATCGATCGTTTATTGCACGATAGCGCCTTTCTTTCTCT GCGCGATCGGTATGGCCATACCCAGGTGGTTGATCTGCTTAGGCGGATGCTTGACGACGCGCGCGACGTCATACGGAATA CGCAAACGCTTCCCGACTGGTACGCAGACTGGGCGCAAGAGGCGAAACTCCGGCTGGAAAATGCGGCGCAAAGCGCGCTG CGCCCGGTGATTAACCTGACGGGGACGGTGCTGCACACCAATCTTGGCCGCGCATTGCAGGCGCAAGAAGCGATTGAGGC GGTAACGCAGGCGATGCGCGCGCCGGTGACGCTGGAATACGATTTAGATGGCGCCGGGCGGGGGCATCGCGACCGGGCGC TGGCGACGCTGTTATGCCGTATCACCGGGGCGGAGGACGCCTGTATCGTCAATAACAATGCGGCGGCGGTATTGCTGATG CTGGCGGCGACCGCCAGCGGCAAAGAGGTGGTGGTTTCGCGTGGCGAACTGGTCGAAATCGGCGGCGCGTTTCGTATTCC GGATGTTATGCGCCAGGCGGGCTGTACGCTGCATGAAGTGGGCACCACCAACCGGACGCACGCGAAAGATTACCGTCAGG CGGTAAATGAAAATACCGGGCTGTTGATGAAGGTGCATACCAGTAATTACAGCATTGAGGGCTTTACCAAAACGGTAGAG GAAGCGGAACTGGCGGAAATCGGGCGAGAGCTGGATATTCCGGTGGTGGCGGATCTGGGCAGCGGTTCGCTGGTGGATTT AAGCCAATATGGCTTACCCAAAGAGCCGATGCCGCAACAGCTCATTGCCGCAGGCGTCAGCCTGGTAAGCTTCTCCGGCG ATAAGTTGTTGGGCGGGCCGCAGGCCGGGATCATCGTCGGCAAAAAAGCGATGATTGCCCAACTGCAAAGCCATCCGCTG AAACGCGCTCTGCGCGCGGATAAAATGACGCTGGCGGCGCTGGAGGCAACGTTACGTCTGTATCTGCACCCGGAAGCGTT GGCGGAGAAATTACCCACCCTGCGTCTGTTAACCCGCAGTGAAGCGTCGATTCGCGAACAAGCGCAGCGGTTACAGGCGC GGTTGGCGGCACGTTACGGCGATGAATTTGCGCTGGAGGTTAAACCCTGTCTGTCGCAAATCGGCAGCGGTTCATTACCG GTAGACCGCCTCCCCAGCGCCGCCATGACCTTTACCCCGCACGACGGGCGCGGTAGTCGGCTGGAGGCGCTGGCGGCCCG CTGGCGCACGCTGCCTGTACCGGTCATTGGCCGAATTTATGATGGCCGTTTATGGCTGGATATGCGCTGTCTTGAAGACG AAAGCCGGTTTATGGAGATGATGCTGAAATGA
Upstream 100 bases:
>100_bases GACGCGCATTATGTCCGCCTGAGCAAACTCACGTTACAATCCCCCTTATGTCGATATCCCTCTCCCGCCAGGAGAGGGCC ACCAACAGCCAGGCATTTTC
Downstream 100 bases:
>100_bases TTATTGCAACTGCCGGACACGTAGACCACGGTAAAACGACGTTGCTCCAGGCGATTACCGGCATTAATGCCGATCGCCTG CCGGAAGAGAAAAAACGCGG
Product: selenocysteine synthase
Products: NA
Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase
Number of amino acids: Translated: 463; Mature: 462
Protein sequence:
>463_residues MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSAL RPVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLM LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVE EAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPL KRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLP VDRLPSAAMTFTPHDGRGSRLEALAARWRTLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK
Sequences:
>Translated_463_residues MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSAL RPVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLM LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVE EAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPL KRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLP VDRLPSAAMTFTPHDGRGSRLEALAARWRTLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK >Mature_462_residues TSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALR PVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLML AATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVEE AELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLK RALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPV DRLPSAAMTFTPHDGRGSRLEALAARWRTLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK
Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
COG id: COG1921
COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]
Gene ontology:
Cell location: Cytoplasm
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the selA family
Homologues:
Organism=Escherichia coli, GI2367248, Length=463, Percent_Identity=86.1771058315335, Blast_Score=777, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): SELA_SALA4 (B5EX94)
Other databases:
- EMBL: CP001138 - RefSeq: YP_002148612.1 - ProteinModelPortal: B5EX94 - GeneID: 6795307 - GenomeReviews: CP001138_GR - KEGG: sea:SeAg_B3897 - HOGENOM: HBG564950 - OMA: KRGDRDD - ProtClustDB: PRK04311 - GO: GO:0005737 - HAMAP: MF_00423 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR018319 - InterPro: IPR004534 - Gene3D: G3DSA:3.40.640.10 - TIGRFAMs: TIGR00474
Pfam domain/function: PF03841 SelA; SSF53383 PyrdxlP-dep_Trfase_major
EC number: =2.9.1.1
Molecular weight: Translated: 50829; Mature: 50698
Theoretical pI: Translated: 7.06; Mature: 7.06
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDW CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH YADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEY HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE DLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEI CCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEECCCEEEE GGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVE CCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEECHHHHHHH EAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGP HHHHHHCCCCCCCCEEEECCCCCEEEHHHCCCCCCCCHHHHHHHCHHHEEECCCCCCCCC QAGIIVGKKAMIAQLQSHPLKRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRS CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHCCHHHHHHCC EASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPVDRLPSAAMTFTPHDGRGSR HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCCCHHHCCCCEEEECCCCCCCHH LEALAARWRTLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK HHHHHHHHCCCCCCHHCEEECCEEEEEEHHHHHHHHHHHHHCC >Mature Secondary Structure TSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDW CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH YADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEY HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE DLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEI CCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEECCCEEEE GGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVE CCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEECHHHHHHH EAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGP HHHHHHCCCCCCCCEEEECCCCCEEEHHHCCCCCCCCHHHHHHHCHHHEEECCCCCCCCC QAGIIVGKKAMIAQLQSHPLKRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRS CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHCCHHHHHHCC EASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPVDRLPSAAMTFTPHDGRGSR HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCCCHHHCCCCEEEECCCCCCCHH LEALAARWRTLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK HHHHHHHHCCCCCCHHCEEECCEEEEEEHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA