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The map label for this gene is gatC [H]

Identifier: 29144027

GI number: 29144027

Start: 3850698

End: 3852056

Strand: Direct

Name: gatC [H]

Synonym: t3736

Alternate gene names: 29144027

Gene position: 3850698-3852056 (Clockwise)

Preceding gene: 29144026

Following gene: 29144028

Centisome position: 80.36

GC content: 47.17

Gene sequence:

>1359_bases
ATGAATGATATAGCACATACTCTCTATACCGTTGTGCAATATGTCCTGGGATTTGGCCCAACGGTTTTATTGCCGCTGGT
CCTTTTTTTCCTGGCATTGTTCTTCAAAGTAAAACCCGCTAAAGCACTTCGCTCATCGTTAATTGTCGGAATAGGGTTTG
TCGGAATTTATGCCATCTTTGACATACTTACCAGCAACGTAGGCCCGGCTGCACAGGCAATGGTTGAGCGAACTGGTATT
AGTCTTCCTGTTGTCGATTTAGGCTGGCCACCATTGGCCGCAATTACCTGGGGCTCACCAATCGCCCCCTTTGTCATTCC
GCTGACGATGCTGATTAATGTCGCCATGCTGGCCCTGAATAAGACACGTACTGTTGATGTCGACATGTGGAACTACTGGC
ACTTTGCCCTGGCGGGAACGCTGGTTTACTACAGCACAGGGAGTTTTGTTTTGGGTCTGTCCGCAGCCGCTATTGCCGCG
ATCGTGGTTCTCAAACTGGCGGACTGGTCAGCGCCATTAGTGGCAAAGTACTTCGGTCTGGAAGGTATTTCACTTCCGAC
CCTGTCATCTGTCGTCTTCTTTCCAATTGGATTGCTGTTCGACAAAATTATCGACAAGATCCCGGGTGTTAACCGTATTC
ATATTGATCCGGAAAACGTTCAGAAAAAAATGGGAATCTTCGGCGAGCCTATGATGGTGGGTACTATTCTGGGGGTCTTG
TTGGGCATCATTGCCGGGTATGACTTTAAACATATCCTGTTGCTGGGGATCAGCATTGGCGGTGTCATGTTCATTCTTCC
GCGTATGGTACGAATTTTGATGGAAGGTTTATTACCTCTGTCTGAAGCCATTAAGAAATATTTGAATGCCAAATATCCTG
GCCGTGATGATCTCTTTATCGGACTGGATATCGCGGTAGCAGTAGGTAACCCAGCCATTATCTCTACAGCACTGATTCTG
ACACCCATCTCTGTCTTCATTGCATTCCTTCTTCCTGGCAATAAAGTCCTGCCACTCGGAGACCTTGCGAACCTGGCAGT
CATGGCTTCCATGATTGTACTGGCATGTCGTGGCAATATTTTCCGGGCTGTGATAACCGCAATTCCTGTTATTATCGCCG
ACTTGTGGATTGCGACCAAAATTGCGCCATTTATTACCGGTATGGCTAAAGATGTCAATTTCAAAATGGCTGAGGGGTCA
AGTGGTCAGGTATCAAGCTTCCTTGATGGCGGTAACCCCTTCCGTTTCTGGCTGCTTGAAATTTTCAACGGAAATATTAT
TGCTATCGGGCTGATTCCTGTGCTTGCGCTGGTTATTTATGGTGTTTTTCGCCTGACAAAAGGAACGGTCTATGCCTGA

Upstream 100 bases:

>100_bases
TTCAATCCTTAAAGGCCAAGCCTGATTTCATAAATAAAAAACAGATAAATTACCCAGGCGCTAACGCGAGGTCTGGTCAC
ATCTGAATAAGAGGTCGGAT

Downstream 100 bases:

>100_bases
TTACCACGCAGCGCTTGTCATTGACATTGGTACAACTAACTGCAAAGTCAGCTGCTATTCCTGTCATGACGTGTCAGTTC
TGGAAGTCCGCAAGTTTCCG

Product: PTS system transporter subunit IIC

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALRSSLIVGIGFVGIYAIFDILTSNVGPAAQAMVERTGI
SLPVVDLGWPPLAAITWGSPIAPFVIPLTMLINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSFVLGLSAAAIAA
IVVLKLADWSAPLVAKYFGLEGISLPTLSSVVFFPIGLLFDKIIDKIPGVNRIHIDPENVQKKMGIFGEPMMVGTILGVL
LGIIAGYDFKHILLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPGRDDLFIGLDIAVAVGNPAIISTALIL
TPISVFIAFLLPGNKVLPLGDLANLAVMASMIVLACRGNIFRAVITAIPVIIADLWIATKIAPFITGMAKDVNFKMAEGS
SGQVSSFLDGGNPFRFWLLEIFNGNIIAIGLIPVLALVIYGVFRLTKGTVYA

Sequences:

>Translated_452_residues
MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALRSSLIVGIGFVGIYAIFDILTSNVGPAAQAMVERTGI
SLPVVDLGWPPLAAITWGSPIAPFVIPLTMLINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSFVLGLSAAAIAA
IVVLKLADWSAPLVAKYFGLEGISLPTLSSVVFFPIGLLFDKIIDKIPGVNRIHIDPENVQKKMGIFGEPMMVGTILGVL
LGIIAGYDFKHILLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPGRDDLFIGLDIAVAVGNPAIISTALIL
TPISVFIAFLLPGNKVLPLGDLANLAVMASMIVLACRGNIFRAVITAIPVIIADLWIATKIAPFITGMAKDVNFKMAEGS
SGQVSSFLDGGNPFRFWLLEIFNGNIIAIGLIPVLALVIYGVFRLTKGTVYA
>Mature_452_residues
MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALRSSLIVGIGFVGIYAIFDILTSNVGPAAQAMVERTGI
SLPVVDLGWPPLAAITWGSPIAPFVIPLTMLINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSFVLGLSAAAIAA
IVVLKLADWSAPLVAKYFGLEGISLPTLSSVVFFPIGLLFDKIIDKIPGVNRIHIDPENVQKKMGIFGEPMMVGTILGVL
LGIIAGYDFKHILLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPGRDDLFIGLDIAVAVGNPAIISTALIL
TPISVFIAFLLPGNKVLPLGDLANLAVMASMIVLACRGNIFRAVITAIPVIIADLWIATKIAPFITGMAKDVNFKMAEGS
SGQVSSFLDGGNPFRFWLLEIFNGNIIAIGLIPVLALVIYGVFRLTKGTVYA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=441, Percent_Identity=39.9092970521542, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI1790758, Length=411, Percent_Identity=38.1995133819951, Blast_Score=284, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 48562; Mature: 48562

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALRSSLIVGIGFVGIYAIF
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
DILTSNVGPAAQAMVERTGISLPVVDLGWPPLAAITWGSPIAPFVIPLTMLINVAMLALN
HHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHC
KTRTVDVDMWNYWHFALAGTLVYYSTGSFVLGLSAAAIAAIVVLKLADWSAPLVAKYFGL
CCCEEEEEHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
EGISLPTLSSVVFFPIGLLFDKIIDKIPGVNRIHIDPENVQKKMGIFGEPMMVGTILGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHH
LGIIAGYDFKHILLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPGRDDLFI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEE
GLDIAVAVGNPAIISTALILTPISVFIAFLLPGNKVLPLGDLANLAVMASMIVLACRGNI
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCHH
FRAVITAIPVIIADLWIATKIAPFITGMAKDVNFKMAEGSSGQVSSFLDGGNPFRFWLLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHCCCCHHHHHHHH
IFNGNIIAIGLIPVLALVIYGVFRLTKGTVYA
HHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALRSSLIVGIGFVGIYAIF
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
DILTSNVGPAAQAMVERTGISLPVVDLGWPPLAAITWGSPIAPFVIPLTMLINVAMLALN
HHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHC
KTRTVDVDMWNYWHFALAGTLVYYSTGSFVLGLSAAAIAAIVVLKLADWSAPLVAKYFGL
CCCEEEEEHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
EGISLPTLSSVVFFPIGLLFDKIIDKIPGVNRIHIDPENVQKKMGIFGEPMMVGTILGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHH
LGIIAGYDFKHILLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPGRDDLFI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEE
GLDIAVAVGNPAIISTALILTPISVFIAFLLPGNKVLPLGDLANLAVMASMIVLACRGNI
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCHH
FRAVITAIPVIIADLWIATKIAPFITGMAKDVNFKMAEGSSGQVSSFLDGGNPFRFWLLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHCCCCHHHHHHHH
IFNGNIIAIGLIPVLALVIYGVFRLTKGTVYA
HHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]