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The map label for this gene is torA

Identifier: 29143989

GI number: 29143989

Start: 3810852

End: 3813404

Strand: Direct

Name: torA

Synonym: t3696

Alternate gene names: 29143989

Gene position: 3810852-3813404 (Clockwise)

Preceding gene: 29143988

Following gene: 29143990

Centisome position: 79.53

GC content: 56.05

Gene sequence:

>2553_bases
ATGAAAAATAAGGACTCGTTACACGTCTCTCGTCGACGTTTTCTGGCGCAGCTTGGCGGCTTGACGGTGGCAGGAATGCT
GGGGCCGTCACTACTGACGCCCCGTAGCGCCCGCGCAGCGGATGCCGTTGCGCCAGGCGCCGCGACGAAAGAGGGTATCC
TTACCGGTTCTCACTGGGGGGCGATTCGCGCCACGGTGGTTGACGGTCGATTTGTGGCGGCAAAACCGTTTGAACAGGAT
AAATACCCGTCCAAAATGATCGCCGGTCTGCCCGATCACGTCCACAACGCGGCGCGTATTCGCTATCCGATGGTGCGCGT
CGACTGGATGCGCAAAGGTCATCAAAGCGACACCTCGCAGCGCGGCGATAATCGTTTTGTGCGCGTCTCCTGGGATGAAG
CGCTGGATCTGTTCTATCAGGAACTGGAGCGGGTGCAAAAAACCTACGGGCCGAGCGCGTTACTGACGGCGAGCGGTTGG
CAATCTACCGGCATGTTCCATAACGCCTCCGGGATGCTGGCGCGCGCGATTGCGCTACATGGCAATAGCGTCAGCACGGG
AGGGGACTATTCGACCGGCGCGGCGCAGGTGATTCTGCCGCGTGTGGTGGGTTCAATGGAAGTGTACGAGCAGCAAACGT
CATGGCCTCTGGTTTTACAGAACAGTAAAACGATTGTGCTATGGGGTTCTGATATGGTGAAAAACCAGCAGGCAAACTGG
TGGTGCCCGGATCACGATGTCTATCAGTACTATGAACAATTAAAAGAGAAGGTTGCCAGCGGCGCTATCTCGGTCATCAG
CATCGACCCGGTCGTCACCTCCACGCACGATTATCTGGGGCGCGATAAGGTCAAACATATCGCCATTAACCCGCAGACGG
ATGTCCCGTTACAACTGGCGCTGGCGCATACCCTGTACAGCGAGAAACTGTACGATAAAAATTTCCTCGATAACTACTGC
GTCGGTTTTGACCAGTTCCTCCCCTATTTGCTGGGCGAGAAAGATGGACAGCCCAAAGATGCCGCCTGGGCGGAAAAACT
GTGCGGTATTGACGCCGACACCATCCGCGCGTTGGCGCGGCAGATGGCGGGCGACAGAACGCAAATCATCGCTGGCTGGT
GCGTACAACGTATGCAGCATGGCGAACAGTGGTCATGGATGGTCGTCGTGCTGGCGGCAATGCTGGGACAGATTGGTTTA
CCGGGCGGCGGCTTTGGTTTTGGCTGGCACTATAACGGCGCCGGGACGCCTGGTCGTAAAGGGATCATTTTAAGCGGCTT
TTCCGGTTCGACGACCGTTCCGCCAGTGCACGACAGCACGGATTACAAAGGCTACAGCAGCACCATTCCTATTGCGCGTT
TTATGGATGCCATTCTTGAACCGGGCAAGATCATTAACTGGAACGGGAAATCGGTTAAATTACCGCCGCTGAAGATGTGC
GTGTTCGCCGGGACCAACCCGTTCCACCGACACCAACAAATTAACCGCATAATTGAAGGCTGGCGCAAGCTGGAAACGGT
CATCGCTATTGATAACCAGTGGACGTCGACCTGCCGCTTTGCGGATATCGTTTTGCCGGCTACCACCCAATTTGAGCGTA
ACGACCTCGATCAGTTCGGCAACCACTCTAACCGCGGCATTATCGCCATGAAACAGGTGGTGTCGCCGCAGTTTGAAGCG
CGTAACGACTTTGATATTTTCCGCGATCTCTGCCGACGCTTTAACCGTGAAGCGGCATTCACGGAAGGTCTTGATGAAAT
GGGCTGGCTGAAACGCATCTGGCAGGAAGGGAGCCAGCAGGGAAAAGGTCGCGGTATCCACTTACCGACTTTCGAGGTGT
TCTGGAATCAACAGGAGTACATCGAGTTTGATCATCCGCAGATGTTTGTGCGCCATCAGGCTTTCCGTGAAGATCCGGAC
CTGGAGCCGTTGGGCACGCCAAGCGGTTTGATCGAGATTTACTCCAAAACGATCGCCGACATGCAATACGACGATTGTCA
GGGCCATCCCATGTGGTTCGAAAAAATCGAACGCTCGCATGGCGGGCCGGGATCGCAGCGCTGGCCGCTGCACTTACAGT
CCGTCCACCCTGATTTCCGTCTGCATTCCCAACTGTGCGAGTCGGAAACGCTGCGTCAGCAATATGCCGTTGGCGGCAAG
GAGCCGGTCTTTATTAACCCACAGGATGCCAGCGCGCGCGGGATCCGCAACGGTGACATCGTGCGGGTATTCAATGCACG
CGGGCAGGTACTGGCGGGAGCGGTAGTTTCCGATCGCTATGCGCCGGGCGTGGCGCGAATTCATGAAGGTGCCTGGTACG
ATCCTGATAAAGGCGGCGATCTCAACGCGTTATGTAAGTACGGCAACCCTAACGTATTAACGCTGGATACCGGTACATCA
CAGCTCGCGCAGGCGACCAGCGCGCATACGACGCTGGTGGAAATTGAAAAATATACCGGTCCTATGGATAACGTCACGGC
GTTTAACGGTCCGGCCGAGATGGTCGCGCAGTGTGAATATGTACCCGCATCGCAGGGGAATCCGCATGATTAA

Upstream 100 bases:

>100_bases
ACCAGTCTGGATAAGCGTGATGAACGTACCTTGTTGAAATATCTCCAGATGAATGCGTCTGATACCACCAACACGCCGCA
CAGCGATAAGGGAGAACACA

Downstream 100 bases:

>100_bases
GCAGCCAGCGCTTGCTCAGGAACAGTACGCCTGCGTATATGCATGGCTGGCGTTACTCTTTTTCCGGGAAGTGGATGATG
AAGGGTTAATACAATTACAG

Product: trimethylamine-N-oxide reductase

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase

Number of amino acids: Translated: 850; Mature: 850

Protein sequence:

>850_residues
MKNKDSLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAVAPGAATKEGILTGSHWGAIRATVVDGRFVAAKPFEQD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQRGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGW
QSTGMFHNASGMLARAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLALAHTLYSEKLYDKNFLDNYC
VGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALARQMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKIINWNGKSVKLPPLKMC
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFGNHSNRGIIAMKQVVSPQFEA
RNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQGKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESETLRQQYAVGGK
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGDLNALCKYGNPNVLTLDTGTS
QLAQATSAHTTLVEIEKYTGPMDNVTAFNGPAEMVAQCEYVPASQGNPHD

Sequences:

>Translated_850_residues
MKNKDSLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAVAPGAATKEGILTGSHWGAIRATVVDGRFVAAKPFEQD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQRGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGW
QSTGMFHNASGMLARAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLALAHTLYSEKLYDKNFLDNYC
VGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALARQMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKIINWNGKSVKLPPLKMC
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFGNHSNRGIIAMKQVVSPQFEA
RNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQGKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESETLRQQYAVGGK
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGDLNALCKYGNPNVLTLDTGTS
QLAQATSAHTTLVEIEKYTGPMDNVTAFNGPAEMVAQCEYVPASQGNPHD
>Mature_850_residues
MKNKDSLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAVAPGAATKEGILTGSHWGAIRATVVDGRFVAAKPFEQD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQRGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGW
QSTGMFHNASGMLARAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLALAHTLYSEKLYDKNFLDNYC
VGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALARQMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKIINWNGKSVKLPPLKMC
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFGNHSNRGIIAMKQVVSPQFEA
RNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQGKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESETLRQQYAVGGK
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGDLNALCKYGNPNVLTLDTGTS
QLAQATSAHTTLVEIEKYTGPMDNVTAFNGPAEMVAQCEYVPASQGNPHD

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787231, Length=845, Percent_Identity=89.8224852071006, Blast_Score=1587, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=834, Percent_Identity=43.5251798561151, Blast_Score=660, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=797, Percent_Identity=43.2873274780427, Blast_Score=623, Evalue=1e-179,
Organism=Escherichia coli, GI87081797, Length=861, Percent_Identity=30.7781649245064, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI1787870, Length=862, Percent_Identity=28.6542923433875, Blast_Score=268, Evalue=1e-72,
Organism=Escherichia coli, GI171474008, Length=750, Percent_Identity=29.3333333333333, Blast_Score=262, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TORA_SALTI (Q8Z2M4)

Other databases:

- EMBL:   AL627280
- EMBL:   AE014613
- RefSeq:   NP_458117.1
- RefSeq:   NP_807331.1
- ProteinModelPortal:   Q8Z2M4
- SMR:   Q8Z2M4
- GeneID:   1068717
- GeneID:   1250203
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t3696
- KEGG:   sty:STY3956
- HOGENOM:   HBG304064
- OMA:   QQYAVGG
- ProtClustDB:   PRK15102
- BioCyc:   SENT209261:T3696-MONOMER
- BioCyc:   SENT220341:STY3956-MONOMER
- BRENDA:   1.7.2.3
- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887
- Gene3D:   G3DSA:2.40.40.20
- TIGRFAMs:   TIGR00509
- TIGRFAMs:   TIGR01409
- TIGRFAMs:   TIGR02164

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: =1.7.2.3

Molecular weight: Translated: 94676; Mature: 94676

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1; PS00490 MOLYBDOPTERIN_PROK_2; PS00932 MOLYBDOPTERIN_PROK_3; PS51318 TAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKDSLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAVAPGAATKEGILTGSHWG
CCCCCHHHHHHHHHHHHHCCCEEEHHCCCHHCCCCCCCHHHHCCCCCCCCCCCEECCCCC
AIRATVVDGRFVAAKPFEQDKYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQ
EEEEEEECCEEEECCCCCCCCCCHHHHHCCCHHHCCHHHEECCCEEEHHHHCCCCCCCCC
RGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGWQSTGMFHNASGMLARAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCHHHHHHHHCC
GNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHCCCCCCC
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLA
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCEEECCHHHHCCCCEEEEEECCCCCCCHHHH
LAHTLYSEKLYDKNFLDNYCVGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALAR
HHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
QMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKIINWNGKSVKLPPLKMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCEEECCHHEEE
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFG
EEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVSPQFEARNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQ
CCCCCCEEEEHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCC
GKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCCCCCCCHHEEECCHHHEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESETLRQQYAVGGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGD
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
LNALCKYGNPNVLTLDTGTSQLAQATSAHTTLVEIEKYTGPMDNVTAFNGPAEMVAQCEY
HHHEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEHHHCCCCCCCEECCCHHHHHHHCCC
VPASQGNPHD
CCCCCCCCCC
>Mature Secondary Structure
MKNKDSLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAVAPGAATKEGILTGSHWG
CCCCCHHHHHHHHHHHHHCCCEEEHHCCCHHCCCCCCCHHHHCCCCCCCCCCCEECCCCC
AIRATVVDGRFVAAKPFEQDKYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQ
EEEEEEECCEEEECCCCCCCCCCHHHHHCCCHHHCCHHHEECCCEEEHHHHCCCCCCCCC
RGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGWQSTGMFHNASGMLARAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCHHHHHHHHCC
GNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHCCCCCCC
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLA
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCEEECCHHHHCCCCEEEEEECCCCCCCHHHH
LAHTLYSEKLYDKNFLDNYCVGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALAR
HHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
QMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKIINWNGKSVKLPPLKMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCEEECCHHEEE
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFG
EEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVSPQFEARNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQ
CCCCCCEEEEHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCC
GKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCCCCCCCHHEEECCHHHEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESETLRQQYAVGGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGD
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
LNALCKYGNPNVLTLDTGTSQLAQATSAHTTLVEIEKYTGPMDNVTAFNGPAEMVAQCEY
HHHEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEHHHCCCCCCCEECCCHHHHHHHCCC
VPASQGNPHD
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504