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The map label for this gene is torC [H]

Identifier: 29143988

GI number: 29143988

Start: 3809678

End: 3810862

Strand: Direct

Name: torC [H]

Synonym: t3695

Alternate gene names: 29143988

Gene position: 3809678-3810862 (Clockwise)

Preceding gene: 29143987

Following gene: 29143989

Centisome position: 79.5

GC content: 52.83

Gene sequence:

>1185_bases
ATGCGAAAACTCTGGAGAGCGTTACTCAGGCCAAGCACCCGTTGGTCGATACTGGCGCTGGTCATTGTCGGGATTGTGAT
CGGCGTTGCGCTGATCGTGTTACCTCACGTCGGTATCAAACTGACCAGTACGACAGAGTTTTGCGTCAGCTGCCATAGTG
TGCAGCCGGTGTATCAGGAATATAAACAGTCCGTACATTTCCAGAACGCTTCCGGCGTACGCGCGGAATGCCACGATTGC
CATATCCCCCCCGATATTCCAGGCATGGTGAAACGTAAGCTGGAAGCCAGCAACGATCTTTACCAGACATTTATCGCCCA
CTCGATTGATACCCCGGAAAAATTTGAAGCTAAACGCGCCGAGCTTGCCGAGCGAGAATGGGCGCGCATGAAAGAGAATA
ACTCCGCGACCTGTCGTTCCTGCCATAACTACGATGCGATGGATCACGCGAAACAGAACCCGGAAGCGGCGCGGCAAATG
AAAATCGCCGCGAAAGAAAATCAATCCTGCATCGACTGCCATAAAGGGATTGCCCACCAGCTACCGGATATGAGCAGCGG
TTTCCGCAAACAGTTTGATGAACTGCGCGCCAGCGCCAGTACGCATAATGACGGCGATACGCTCTATTCGCTGGATATCA
AGCCGATTTACGCCGCTAAAGGCGATAAAGAACCGGCAGGTTCGCTGTTGCCTGCTTCTGAAGTGAAAGTCCTTAAACGG
GACGGTGACTGGCTGCAAGTGCAAATCGAAGGCTGGACGGAGACGGACGGTCGCCAGCGCGTGCTGACGCAGTTGCCCGG
TAAACGTATTTTTGTCGCCTCGATTCGCGGCGATGTGCAACAGCATGTGAAAACGCTGGAAGAGACCACCGTCGCGGCGA
CCAATACTCAGTGGAGCAAATTACAGGCAACCGCGTGGATGCAAAAAGGTGACATGGTAAATGACATTAAACCGATTTGG
GCCTATGCCGACTCCCTCTATAACGGCACCTGTAATCAGTGTCACGGTGCGCCGGACAAAGCGCACTTTGACGCTAACGG
CTGGATCGGCACGCTCAACGGCATGATCGGTTTCACCAGTCTGGATAAGCGTGATGAACGTACCTTGTTGAAATATCTCC
AGATGAATGCGTCTGATACCACCAACACGCCGCACAGCGATAAGGGAGAACACAATGAAAAATAA

Upstream 100 bases:

>100_bases
TGTTCATATATTGCCGTATCCCGTTCATCCTGACCAGTGACGCTGTTCATATTTGCGGAATAAGATCTGCGCATTAAACC
ATATAATTACAGGGGCTATT

Downstream 100 bases:

>100_bases
GGACTCGTTACACGTCTCTCGTCGACGTTTTCTGGCGCAGCTTGGCGGCTTGACGGTGGCAGGAATGCTGGGGCCGTCAC
TACTGACGCCCCGTAGCGCC

Product: hypothetical protein

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRKLWRALLRPSTRWSILALVIVGIVIGVALIVLPHVGIKLTSTTEFCVSCHSVQPVYQEYKQSVHFQNASGVRAECHDC
HIPPDIPGMVKRKLEASNDLYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQNPEAARQM
KIAAKENQSCIDCHKGIAHQLPDMSSGFRKQFDELRASASTHNDGDTLYSLDIKPIYAAKGDKEPAGSLLPASEVKVLKR
DGDWLQVQIEGWTETDGRQRVLTQLPGKRIFVASIRGDVQQHVKTLEETTVAATNTQWSKLQATAWMQKGDMVNDIKPIW
AYADSLYNGTCNQCHGAPDKAHFDANGWIGTLNGMIGFTSLDKRDERTLLKYLQMNASDTTNTPHSDKGEHNEK

Sequences:

>Translated_394_residues
MRKLWRALLRPSTRWSILALVIVGIVIGVALIVLPHVGIKLTSTTEFCVSCHSVQPVYQEYKQSVHFQNASGVRAECHDC
HIPPDIPGMVKRKLEASNDLYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQNPEAARQM
KIAAKENQSCIDCHKGIAHQLPDMSSGFRKQFDELRASASTHNDGDTLYSLDIKPIYAAKGDKEPAGSLLPASEVKVLKR
DGDWLQVQIEGWTETDGRQRVLTQLPGKRIFVASIRGDVQQHVKTLEETTVAATNTQWSKLQATAWMQKGDMVNDIKPIW
AYADSLYNGTCNQCHGAPDKAHFDANGWIGTLNGMIGFTSLDKRDERTLLKYLQMNASDTTNTPHSDKGEHNEK
>Mature_394_residues
MRKLWRALLRPSTRWSILALVIVGIVIGVALIVLPHVGIKLTSTTEFCVSCHSVQPVYQEYKQSVHFQNASGVRAECHDC
HIPPDIPGMVKRKLEASNDLYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQNPEAARQM
KIAAKENQSCIDCHKGIAHQLPDMSSGFRKQFDELRASASTHNDGDTLYSLDIKPIYAAKGDKEPAGSLLPASEVKVLKR
DGDWLQVQIEGWTETDGRQRVLTQLPGKRIFVASIRGDVQQHVKTLEETTVAATNTQWSKLQATAWMQKGDMVNDIKPIW
AYADSLYNGTCNQCHGAPDKAHFDANGWIGTLNGMIGFTSLDKRDERTLLKYLQMNASDTTNTPHSDKGEHNEK

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=390, Percent_Identity=89.2307692307692, Blast_Score=744, Evalue=0.0,
Organism=Escherichia coli, GI1788181, Length=373, Percent_Identity=32.7077747989276, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1788530, Length=186, Percent_Identity=48.3870967741936, Blast_Score=181, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 44183; Mature: 44183

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLWRALLRPSTRWSILALVIVGIVIGVALIVLPHVGIKLTSTTEFCVSCHSVQPVYQE
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCHHHHH
YKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDLYQTFIAHSIDTPEKFEAKRA
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHH
ELAEREWARMKENNSATCRSCHNYDAMDHAKQNPEAARQMKIAAKENQSCIDCHKGIAHQ
HHHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
LPDMSSGFRKQFDELRASASTHNDGDTLYSLDIKPIYAAKGDKEPAGSLLPASEVKVLKR
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHHHEEC
DGDWLQVQIEGWTETDGRQRVLTQLPGKRIFVASIRGDVQQHVKTLEETTVAATNTQWSK
CCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHEECCCHHHH
LQATAWMQKGDMVNDIKPIWAYADSLYNGTCNQCHGAPDKAHFDANGWIGTLNGMIGFTS
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEECCCCCEEECCCCEECCC
LDKRDERTLLKYLQMNASDTTNTPHSDKGEHNEK
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRKLWRALLRPSTRWSILALVIVGIVIGVALIVLPHVGIKLTSTTEFCVSCHSVQPVYQE
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCCHHHHH
YKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDLYQTFIAHSIDTPEKFEAKRA
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHH
ELAEREWARMKENNSATCRSCHNYDAMDHAKQNPEAARQMKIAAKENQSCIDCHKGIAHQ
HHHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
LPDMSSGFRKQFDELRASASTHNDGDTLYSLDIKPIYAAKGDKEPAGSLLPASEVKVLKR
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHHHEEC
DGDWLQVQIEGWTETDGRQRVLTQLPGKRIFVASIRGDVQQHVKTLEETTVAATNTQWSK
CCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHEECCCHHHH
LQATAWMQKGDMVNDIKPIWAYADSLYNGTCNQCHGAPDKAHFDANGWIGTLNGMIGFTS
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEECCCCCEEECCCCEECCC
LDKRDERTLLKYLQMNASDTTNTPHSDKGEHNEK
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]