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The map label for this gene is ydeV [H]

Identifier: 29143851

GI number: 29143851

Start: 3648892

End: 3650484

Strand: Direct

Name: ydeV [H]

Synonym: t3546

Alternate gene names: 29143851

Gene position: 3648892-3650484 (Clockwise)

Preceding gene: 29143850

Following gene: 29143852

Centisome position: 76.15

GC content: 54.99

Gene sequence:

>1593_bases
ATGGCTCGACTCTGTACCCATACTGAATCAGGACATTACCTGATGGCTCTTGACGCCGGTACCGGTAGCGTCAGAGCAGT
AATTTTTGATCTACAAGGAAAGCAAATAGCTGTCGGTCAAGCGGAATGGCAGCATCTGGCCGTGCCGGATGTGCCTGGTT
CGATGGAGTTTGATCTTGCCAAAAACTGGCAACTGGCTTGCCAGTGTATCCGTCAGGCACTACAGAAAGCCGCCATCCCT
GCAACGGCTATCGCTGCCGTATCGGCCTGTTCGATGCGTGAAGGCATTGTTATTTATGACAGTAACGGCGAACCCATTTG
GGCCTGCGCTAATGTTGACGCCCGCGCGGCGCACGAAGTCAGTGAATTAAAAGAGCTGCACGATAACACCTTTGAGGAGG
AAGTTTATCGTTGCTCCGGGCAAACGCTGGCGCTCAGCGCTATTCCGCGTCTGCTCTGGCTTGCCCACCATCGTCCGGAT
ATTTATCATCGCGCGTCAACCGTCACTATGATCAGCGACTGGATGGCCTTTATGCTCAGCGGCGAACTGGCGGTCGATCC
CTCCAACGCAGGCACGACGGGGTTATTGGATCTGGTGACCCGCAACTGGAAACGTAGTCTGTTACAGATGGCGGGCCTGC
GTTCTGACATTCTCTCGCCGGTAAAAGAAACCGGGACACTGCTCGGTCACATTTCACAGAAAGCGGCTGAACAGTGCGAC
CTGCAAGCGGGTACGCCGGTCATCGTTGGCGGCGGCGATGTGCAGTTAGGCTGTCTGGGGCTGGGCGTCGTACGCCCGGC
GCAAACGGCCGTGCTGGGCGGAACCTTCTGGCAACAGGTCGTCAATCTTCCCGCGCCGGTCACCGACCCAAACATGAACG
TTCGCATCAATCCTCATGTGATCCCCGGTATGGTACAAACCGAGTCTATTAGCTTTTTTACTGGGTTAACGATGCGTTGG
TTCCGCGACGCCTTTTGCGCCGAGGAAAAACTAATCGCTGAAAGGTTAGGTATTGATGCGTATTCCCTGCTGGAAGATAT
GGCCAGCCGGGTGCCTCCCGGCGCGCACGGTGTGATGCCCATCTTCTCTGACGTTATGCGTTTTAAACGCTGGTACCATG
CCGCGCCGTCGTTTATCAATCTGTCTATCGATCCTGAAAAATGTAATAAAGCGACCCTATTTCGCGCGCTGGAAGAGAAT
GCCGCCATTGTTTCCGCCTGCAATTTACAGCAAATTGCCGCGTTTTCCGGCGTACAGGCCGACTCGCTGGTTTTTGCCGG
CGGAGGATCTAAAGGCAAATTATGGAGCCAAATCCTTGCCGACGTTACGGGACTCACCGTTCACGTACCTGTCGTCAAAG
AAGCTACCGCGCTAGGGTGCGCTATTGCCGCAGGCGTTGGCGTGGGTATCTGGCCATCGCTGGCGGAAACGGGAGAAAAG
CTAGTGCGCTGGGATCGGGAGCATAAACCTAATCCTGAAAATTTCGCTGTCTATCAGCAGGCCAGAGAAAAATGGCAGGC
CGTTTATCAGGATCAACGCGCGCTGGTCGATGGTGGCTTAACGACATCCCTCTGGAAAGCGCCAGGCCTGTAA

Upstream 100 bases:

>100_bases
TTATTGAAAAATAAAAAATAAAATAACACTTACCTCAATTCAATAAACAATAACTGACAGGATTTTATGTAACGATGTAA
AAATAGCCGAGGGTAAAAAA

Downstream 100 bases:

>100_bases
CAGGAGAATAAGCATGCAAAAAACGAATGAGAAGAATCATGAATACCGCTTTAGTGATAATGGCCCTAAATACTTAATCC
GTGGGCCGGGCTGCGATATG

Product: autoinducer-2 (AI-2) kinase

Products: NA

Alternate protein names: AI-2 kinase [H]

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIP
ATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEVSELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPD
IYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCD
LQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRW
FRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAHGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEEN
AAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGIWPSLAETGEK
LVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL

Sequences:

>Translated_530_residues
MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIP
ATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEVSELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPD
IYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCD
LQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRW
FRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAHGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEEN
AAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGIWPSLAETGEK
LVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
>Mature_529_residues
ARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIPA
TAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEVSELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDI
YHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCDL
QAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRWF
RDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAHGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENA
AIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGIWPSLAETGEKL
VRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL

Specific function: Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787789, Length=530, Percent_Identity=83.0188679245283, Blast_Score=916, Evalue=0.0,
Organism=Escherichia coli, GI1790361, Length=496, Percent_Identity=26.6129032258064, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1790005, Length=499, Percent_Identity=22.8456913827655, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789138, Length=477, Percent_Identity=23.6897274633124, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789168, Length=505, Percent_Identity=23.960396039604, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1789987, Length=507, Percent_Identity=24.0631163708087, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=472, Percent_Identity=23.728813559322, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: NA

Molecular weight: Translated: 57402; Mature: 57271

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLA
CCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECCCCCCEEECCCCCCCCCCCCC
KNWQLACQCIRQALQKAAIPATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCHHHHHHH
SELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDIYHRASTVTMISDWMAFMLS
HHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
GELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCD
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHV
CCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
IPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAHGVMP
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHH
IFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLQQIAAFSGVQA
HHHHHHHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCC
DSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGIWPSLAETGEK
CCEEEECCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
ARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLA
CCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECCCCCCEEECCCCCCCCCCCCC
KNWQLACQCIRQALQKAAIPATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCHHHHHHH
SELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDIYHRASTVTMISDWMAFMLS
HHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
GELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCD
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHV
CCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
IPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAHGVMP
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHH
IFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLQQIAAFSGVQA
HHHHHHHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCC
DSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGIWPSLAETGEK
CCEEEECCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA