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The map label for this gene is hdfR

Identifier: 29143768

GI number: 29143768

Start: 3537240

End: 3538076

Strand: Direct

Name: hdfR

Synonym: t3449

Alternate gene names: 29143768

Gene position: 3537240-3538076 (Clockwise)

Preceding gene: 29143766

Following gene: 29143769

Centisome position: 73.82

GC content: 51.49

Gene sequence:

>837_bases
GTGGATACGGAATTGTTAAAAACTTTCCTGGAAGTTAGCCGGACACGCCATTTCGGGCGGGCCGCAGAAGCACTTTACCT
GACGCAATCCGCGGTGAGCTTTCGTATCAGGCAACTGGAGAATCAACTGGGCGTAAACCTTTTTACGCGGCACAGAAACA
ATATCCGTTTAACCACGGCTGGCGAAAAACTTTTACCGTATGCGGAAACGCTGATGAATACGTGGCAGGCGGCACGTAAA
GAGGTGGCGCATACCTCACGCCATAACGAGTTTTCCATCGGCGCCAGCGCGTCTTTATGGGAGTGTATGCTTAACGCCTG
GCTGGGTCGACTGTACCAACTACAGGAGCCGCAAAGCGGCCTGCAGTTCGAAGCCAGAATCGCTCAACGGCAATCGCTTG
TGAAGCAACTTCATGAACGCCAGCTTGATCTCCTCATTACTACCGAAGCGCCCAAAATGGATGAGTTCAGCAGTCAGCTG
TTAGGGCACTTCACTTTGGCGTTATATTGCAGCAGCCCTGCCCGTAAGAAATCAGAACTCAATTATCTGCGGCTGGAGTG
GGGACCAGACTTCCAACAGCATGAAACAGGGCTGATCGCAGCAGATGAAGTACCGGTATTAACAACCAGCTCAGCCGAAC
TCGCCCGACAGCAGCTTAGCGCATTAAATGGCTGTAGCTGGCTTCCTGTAAACTGGGCAAATGAAAAGGGCGGATTACAT
ACCGTTGCCGACAGCGCAACGCTTTCACGGCCGCTATACGCCATTTGGCTGCAAAACAGCGATAAATACTCGCTGATCTG
CGATCTGTTAAAAACGGATGTGCTGGATGAACAATGA

Upstream 100 bases:

>100_bases
TTTGTCTGAGCTATTTATGGCGCGGAGTATTAGTTACGCTTGACAGAGTGTAAAACAAAACATTTAAATCATAACGACAA
ATAATTTTGTGGAGAGCACA

Downstream 100 bases:

>100_bases
AAATGATGAAAAGAAAAAGAAGGGAACTTACGATTACCTGATCAGATAATCAGGTAATTTCAGGCAAAAAAAAATCCTTA
GCAGATGCTAAGGATTATTT

Product: transcriptional regulator HdfR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARK
EVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWANEKGGLH
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDEQ

Sequences:

>Translated_278_residues
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARK
EVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWANEKGGLH
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDEQ
>Mature_278_residues
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARK
EVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWANEKGGLH
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDEQ

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI48994962, Length=277, Percent_Identity=87.3646209386281, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1787601, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788626, Length=151, Percent_Identity=31.1258278145695, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=64, Percent_Identity=48.4375, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=68, Percent_Identity=45.5882352941176, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HDFR_SALA4 (B5EZ22)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002148826.1
- ProteinModelPortal:   B5EZ22
- PRIDE:   B5EZ22
- GeneID:   6794943
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B4123
- HOGENOM:   HBG536341
- OMA:   LHVGLPG
- ProtClustDB:   PRK03601
- HAMAP:   MF_01233
- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 31604; Mature: 31604

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
GEKLLPYAETLMNTWQAARKEVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
LQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGHFTLALYCSSPARKKSEL
CHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCC
NYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWANEKGGLH
CEEEEECCCCHHHHCCCEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDEQ
EEECCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
GEKLLPYAETLMNTWQAARKEVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
LQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGHFTLALYCSSPARKKSEL
CHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCC
NYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWANEKGGLH
CEEEEECCCCHHHHCCCEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDEQ
EEECCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA