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The map label for this gene is cheM [H]

Identifier: 29143476

GI number: 29143476

Start: 3223797

End: 3225365

Strand: Reverse

Name: cheM [H]

Synonym: t3136

Alternate gene names: 29143476

Gene position: 3225365-3223797 (Counterclockwise)

Preceding gene: 29143477

Following gene: 29143474

Centisome position: 67.31

GC content: 50.1

Gene sequence:

>1569_bases
ATGTTTTTGCATAACATTAAAATACGTTCAAAATTATTTATGGCCTTTGGCTTATTCATTGTTCTCATGGTGGTGAGTTC
CGCTCTGTCTTTGTTTAGCCTTGATCGGGCTAATACGGGTATGCAGGACATTATTACCAATGATTATCCCACCACGGTAA
AAGCCAATCTGTTAATCGATAATTTTAATGATTTCATCATCGCGCAGCAGCTCATGTTACTGGATGAAGAGGGGCGCTGG
AGCCAGAGCTCGCAGAAAGAACTCAGTGAGATAAGCCAGCGCATTTCGGCGTTACTGGATGAGCTTTCCAGGGAAAATAG
TCACGATGCGGATTCACAGAAAATCATTAATGAAATCCGTGAAGCGCGCCAGCAATACCTGGAGTCCAGATTCCGTATTT
TGAAAGATATTCAAAGCAATAATCGTCAGGCGGCCATTCAGGAGATGATGACCAGAACGGTGCAGGTGCAAAAAGTCTAT
AAGGACAAAGTCCAGGAACTTATCGCTGTTCAGGACGCGCTGATGCATGAAGCGAGCGTGCAGGTCAAAGAGGATTTTAA
AAATAATCGGACGTTGTTAATCACTTTGGCGCTGATAAGCATCGCCGCCGGAGGCGTAATAGGATGGTATATTGTGCGTT
CTATTACCCGACCGCTTGATGACGCGGTACGCTTTGCCGAGGCGATTGCCGATGGCGATCTGACTCGCCATATCACCACC
GACTATAAAGATGAAACAGGCGTACTACTGCAAGCGTTAATGGCGATGAAAACGCGTCTGCTGGATATCGTACAGGAAGT
GCAAAACGGTTCGGAGAGTATCTCCACGGCGGCGGCGCAAATTGTCGCCGGTAACCAGGATTTGGCGGCGCGTACGGAAG
AGCAGGCCAGCTCGGTTGAAGAAACGGCGGCGTCGATGGAACAGATTACCGCCACGGTTAAAAACACAGCCGATCATACC
AGTGAAGCGACCAAACTCTCTGCTGGCGCCGCCAGCGTAGTGAAAAACAATGGGGAGATGATGAATCAAGTGACGCAGAA
AATGCGCGTCATTAACGATACGGCAAATCGTATGTCGGATATCATCAATATCATTGATTCCATTGCCTTTCAGACCAATA
TTCTGGCGCTGAACGCGGCGGTTGAAGCGGCGCGCGCGGGCGAACATGGGCGCGGTTTTGCCGTTGTCGCCGGAGAGGTT
CGCCAGTTGGCGCAAAAGAGCGCCTCGTCGGCCAGTGAAATCCGTAATTTGATTGAAGATTCAACCAGTCAGACTCAGGA
AGGGATGCACCTGGTGGAGAAAGCCAGCGCCCTGATTAATGGCATGGTGGACAACGTCGAAGAGATGGATGTGATATTAC
GTGAGATTGGGCAGGCCAGCCGCGAGCAAACTGACGGTATTTCGCAGATTAACAGCGCGATTGGCCTGATTGACGCCGCC
ACGCAACAAAACTCCTGCCTTGTGGAAGAGTCTGTTGCCGCCGCAGCGTCGCTGAACGAACAGGCGTTACATTTAAAAGA
GCTGGTTAACGTGTTCCGCGTCCGCGAAGAGGACACGCAGCCCGCTTAA

Upstream 100 bases:

>100_bases
AATAATGTTCCGAAATAAAAAGCGATCAATATCATAAAGTTAGTAACATTATTGCCGATAAATCTTCCTGTATGAGGATA
TGCGATCCCAGGGAGAAAAT

Downstream 100 bases:

>100_bases
TCCAGTTCGGCGATTTCCAGCGCCGCGCGATCAATCACGCCGATAATGCGTTTGATTTGCGCGTCGTTGATATCGCTGTG
GTTTATCCGCAGATCCAGCA

Product: methyl-accepting chemotaxis protein II

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MFLHNIKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQDIITNDYPTTVKANLLIDNFNDFIIAQQLMLLDEEGRW
SQSSQKELSEISQRISALLDELSRENSHDADSQKIINEIREARQQYLESRFRILKDIQSNNRQAAIQEMMTRTVQVQKVY
KDKVQELIAVQDALMHEASVQVKEDFKNNRTLLITLALISIAAGGVIGWYIVRSITRPLDDAVRFAEAIADGDLTRHITT
DYKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQIVAGNQDLAARTEEQASSVEETAASMEQITATVKNTADHT
SEATKLSAGAASVVKNNGEMMNQVTQKMRVINDTANRMSDIINIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAGEV
RQLAQKSASSASEIRNLIEDSTSQTQEGMHLVEKASALINGMVDNVEEMDVILREIGQASREQTDGISQINSAIGLIDAA
TQQNSCLVEESVAAAASLNEQALHLKELVNVFRVREEDTQPA

Sequences:

>Translated_522_residues
MFLHNIKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQDIITNDYPTTVKANLLIDNFNDFIIAQQLMLLDEEGRW
SQSSQKELSEISQRISALLDELSRENSHDADSQKIINEIREARQQYLESRFRILKDIQSNNRQAAIQEMMTRTVQVQKVY
KDKVQELIAVQDALMHEASVQVKEDFKNNRTLLITLALISIAAGGVIGWYIVRSITRPLDDAVRFAEAIADGDLTRHITT
DYKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQIVAGNQDLAARTEEQASSVEETAASMEQITATVKNTADHT
SEATKLSAGAASVVKNNGEMMNQVTQKMRVINDTANRMSDIINIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAGEV
RQLAQKSASSASEIRNLIEDSTSQTQEGMHLVEKASALINGMVDNVEEMDVILREIGQASREQTDGISQINSAIGLIDAA
TQQNSCLVEESVAAAASLNEQALHLKELVNVFRVREEDTQPA
>Mature_522_residues
MFLHNIKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQDIITNDYPTTVKANLLIDNFNDFIIAQQLMLLDEEGRW
SQSSQKELSEISQRISALLDELSRENSHDADSQKIINEIREARQQYLESRFRILKDIQSNNRQAAIQEMMTRTVQVQKVY
KDKVQELIAVQDALMHEASVQVKEDFKNNRTLLITLALISIAAGGVIGWYIVRSITRPLDDAVRFAEAIADGDLTRHITT
DYKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQIVAGNQDLAARTEEQASSVEETAASMEQITATVKNTADHT
SEATKLSAGAASVVKNNGEMMNQVTQKMRVINDTANRMSDIINIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAGEV
RQLAQKSASSASEIRNLIEDSTSQTQEGMHLVEKASALINGMVDNVEEMDVILREIGQASREQTDGISQINSAIGLIDAA
TQQNSCLVEESVAAAASLNEQALHLKELVNVFRVREEDTQPA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=533, Percent_Identity=35.4596622889306, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1788194, Length=345, Percent_Identity=41.7391304347826, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1788195, Length=307, Percent_Identity=49.185667752443, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI2367378, Length=310, Percent_Identity=48.3870967741936, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789453, Length=327, Percent_Identity=37.0030581039755, Blast_Score=181, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57412; Mature: 57412

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLHNIKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQDIITNDYPTTVKANLLID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEE
NFNDFIIAQQLMLLDEEGRWSQSSQKELSEISQRISALLDELSRENSHDADSQKIINEIR
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
EARQQYLESRFRILKDIQSNNRQAAIQEMMTRTVQVQKVYKDKVQELIAVQDALMHEASV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVKEDFKNNRTLLITLALISIAAGGVIGWYIVRSITRPLDDAVRFAEAIADGDLTRHITT
HHHHHHCCCCEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
DYKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQIVAGNQDLAARTEEQASSVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ETAASMEQITATVKNTADHTSEATKLSAGAASVVKNNGEMMNQVTQKMRVINDTANRMSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IINIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAGEVRQLAQKSASSASEIRNLIED
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHC
STSQTQEGMHLVEKASALINGMVDNVEEMDVILREIGQASREQTDGISQINSAIGLIDAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TQQNSCLVEESVAAAASLNEQALHLKELVNVFRVREEDTQPA
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFLHNIKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQDIITNDYPTTVKANLLID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEE
NFNDFIIAQQLMLLDEEGRWSQSSQKELSEISQRISALLDELSRENSHDADSQKIINEIR
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
EARQQYLESRFRILKDIQSNNRQAAIQEMMTRTVQVQKVYKDKVQELIAVQDALMHEASV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVKEDFKNNRTLLITLALISIAAGGVIGWYIVRSITRPLDDAVRFAEAIADGDLTRHITT
HHHHHHCCCCEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
DYKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQIVAGNQDLAARTEEQASSVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ETAASMEQITATVKNTADHTSEATKLSAGAASVVKNNGEMMNQVTQKMRVINDTANRMSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IINIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAGEVRQLAQKSASSASEIRNLIED
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHC
STSQTQEGMHLVEKASALINGMVDNVEEMDVILREIGQASREQTDGISQINSAIGLIDAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TQQNSCLVEESVAAAASLNEQALHLKELVNVFRVREEDTQPA
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]