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The map label for this gene is qseB

Identifier: 29143440

GI number: 29143440

Start: 3183796

End: 3184455

Strand: Direct

Name: qseB

Synonym: t3098

Alternate gene names: 29143440

Gene position: 3183796-3184455 (Clockwise)

Preceding gene: 29143429

Following gene: 29143441

Centisome position: 66.44

GC content: 55.45

Gene sequence:

>660_bases
ATGCGAATTTTACTGGTAGAAGATGACACACTTATTGGCGATGGCATAAAAGCAGGTCTGAGTAAAATGGGTTTCAGCGT
CGACTGGTTTACCGAGGGACGTCCGGGCAAAGAGGCGCTTTACAGCGCGCCTTATGATGCGGTCATTTTAGATTTAACGC
TGCCAGGAATGGACGGACGGGATATTTTGCGCGAATGGCGCGAAAAGGGTAAACAGGAACCAGTACTGATCCTGACGGCG
CGCGACGCGTTAGCAGAGCGCGTCGAGGGGCTACGTCTGGGCGCCGATGACTATTTATGTAAACCTTTCGCGCTCATTGA
GGTCGCCGCCCGTCTGGAGGCGCTGGTACGCCGCGCCAGCGGTCAGGCCAGTAGCGAATTGCGCCACGGCCAGGTGACGC
TCAATCCAGGCAATCTCGTCGCGACGCTTGCCGGCGAACCGCTGGCCCTAAAACCAAAAGAGTTCGCGTTGCTGGAACTC
TTACTGCGCAACAAAGGTCGCGTGCTACCGCGCAAGCTTATTGAAGAGAAGCTGTATAACTGGGATGACGACGTGTCCAG
CAATGCAGTGGAAGTCCATGTTCATCATTTACGCCGCAAGCTCGGCAGCGAATTTATTCGCACCGTACACGGCATCGGCT
ACACCCTGGGTGACGCATGA

Upstream 100 bases:

>100_bases
TAACAACTTCTTAAGGCAAAAAAAGATTCTTTTTTTCTGTACATCGCCTGCGGCGACAAGGTTAACTGACGGCAACGCGA
GTTACCGCAGGGAAGAACAG

Downstream 100 bases:

>100_bases
AATTGACGCAACGTCTCAGCCTGCGCGTCAGGCTGACGCTTATTTTCCTGATTCTGGTCTCCATCACCTGGGCAATTTCC
AGTTTTGTGGCCTGGAGAAA

Product: DNA-binding transcriptional regulator QseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGKQEPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALVRRASGQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLEL
LLRNKGRVLPRKLIEEKLYNWDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGDA

Sequences:

>Translated_219_residues
MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGKQEPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALVRRASGQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLEL
LLRNKGRVLPRKLIEEKLYNWDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGDA
>Mature_219_residues
MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGKQEPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALVRRASGQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLEL
LLRNKGRVLPRKLIEEKLYNWDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGDA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=87.6146788990826, Blast_Score=392, Evalue=1e-111,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=46.7592592592593, Blast_Score=191, Evalue=3e-50,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=40.2714932126697, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=36.3636363636364, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=35.9090909090909, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=33.6363636363636, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=35.2941176470588, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=31.8385650224215, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=34.6320346320346, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.5154185022026, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=33.6363636363636, Blast_Score=98, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=27.7533039647577, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=29.0748898678414, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=30.5676855895196, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788550, Length=130, Percent_Identity=33.8461538461538, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=133, Percent_Identity=33.0827067669173, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790437, Length=111, Percent_Identity=35.1351351351351, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=32.6732673267327, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=118, Percent_Identity=35.5932203389831, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): QSEB_SALTI (P66796)

Other databases:

- EMBL:   AL627277
- EMBL:   AE014613
- RefSeq:   NP_457570.1
- RefSeq:   NP_806782.1
- ProteinModelPortal:   P66796
- SMR:   P66796
- PRIDE:   P66796
- GeneID:   1069492
- GeneID:   1249620
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t3098
- KEGG:   sty:STY3354
- HOGENOM:   HBG753323
- OMA:   FSIDWFT
- ProtClustDB:   PRK10336
- BioCyc:   SENT209261:T3098-MONOMER
- BioCyc:   SENT220341:STY3354-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 24274; Mature: 24274

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAPYDAVILDLTLPGMDGR
CEEEEECCCCEECCHHHHHHHHHCCEEEECCCCCCCHHHHHCCCCCEEEEEEECCCCCCH
DILREWREKGKQEPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALVRRAS
HHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHC
GQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLELLLRNKGRVLPRKLIEEKLYN
CCCHHHHCCCEEEECCCCEEEEECCCCEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
WDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGDA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCC
>Mature Secondary Structure
MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAPYDAVILDLTLPGMDGR
CEEEEECCCCEECCHHHHHHHHHCCEEEECCCCCCCHHHHHCCCCCEEEEEEECCCCCCH
DILREWREKGKQEPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALVRRAS
HHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHC
GQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLELLLRNKGRVLPRKLIEEKLYN
CCCHHHHCCCEEEECCCCEEEEECCCCEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
WDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGDA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504