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The map label for this gene is qseC

Identifier: 29143441

GI number: 29143441

Start: 3184452

End: 3185801

Strand: Direct

Name: qseC

Synonym: t3099

Alternate gene names: 29143441

Gene position: 3184452-3185801 (Clockwise)

Preceding gene: 29143440

Following gene: 29143442

Centisome position: 66.45

GC content: 56.67

Gene sequence:

>1350_bases
ATGAAATTGACGCAACGTCTCAGCCTGCGCGTCAGGCTGACGCTTATTTTCCTGATTCTGGTCTCCATCACCTGGGCAAT
TTCCAGTTTTGTGGCCTGGAGAAAGACGACGGATAATGTCGATGAGCTGTTTGACACACAGTTGATGTTGTTCGCCAGAC
GGCTTAGCACCCTCGATCTTAACGAGCTCAACGCCCCGCAGCGCATGGCGCATACGCCAAAGAAATTAAAACATGGGCAT
ATCGATGACGATGCGCTGGCGTTCGCCATCTTTTCCGCTGACGGCAAAATGTTGCTGCATGATGGCGACAACGGCCAGGA
TATTCCGTATCGCTATCGCCGGGAAGGTTTCGACAATGGCTATCTGAAGGATGACAACGACCTCTGGCGTTTTTTGTGGT
TGAACTCGGCGGACGGCAAGTATCGTATCGTCGTCGGTCAGGAGTGGGATTACCGCGAAGATATGGCGCTGGCGATCGTG
GCGGCGCAATTAACGCCGTGGCTGATCGCCCTTCCCTTCATGCTGCTGATTTTATTACTCCTGCTTCACCGCGAGCTCAG
ACCGTTGAAAAAACTGGCGCAGGCGCTGCGCTTCCGGTCGCCGGAATCGGAAACGCCGCTCGACGCCAAAGGCGTACCGA
GCGAGGTTCGCCCACTGGTCGAAGCGCTTAATCAGCTTTTTAGCCGCATCCACTCCATGATGGTGCGCGAACGGCGATTT
ACCTCCGACGCCGCCCATGAATTGCGCAGCCCGCTGGCCGCGCTGAAAGTACAAACCGAGGTGGCGCAGCTCTCGGGCGA
CGATCCGCTATCGCGTGATAAAGCGCTGACCCAGCTCCATGCGGGGATCGATCGCGCCACGCGGCTGGTCGATCAGCTAC
TGACGTTATCGCGTCTCGACTCGCTCAATAATTTGCAGGATGTAGCGGAGATTTCGCTGGAAGAGCTGCTGCAGTCCGCG
GTAATGGATATTTATCATCCGGCGCAGCAGGCGAATATCGACGTGCGTTTACAGCTTAACGCCCATGACGTCATACGTAC
CGGCCAGCCGCTACTCTTAAGCCTGTTAGTGCGTAACCTGCTGGATAATGCGATTCGCTACAGTCCGCAGGGCAGCGTCG
TCGACGTTACCTTACATGCCCGCAGCTTCACCGTCAGAGATAATGGCCCCGGCGTAGCGCCAGAGATTCTAACGCATATC
GGCGAGCGTTTTTACCGCCCGCCAGGCCAAAGTGTGACCGGCAGCGGTCTGGGATTATCAATCGTCCGCCGCATCGCTAC
GCTGCACGGCATGACGGTGTCGTTTGGCAACGCCGCGGAAGGTGGATTTGAGGCCGTAGTACGCTGGTAG

Upstream 100 bases:

>100_bases
CCAGCAATGCAGTGGAAGTCCATGTTCATCATTTACGCCGCAAGCTCGGCAGCGAATTTATTCGCACCGTACACGGCATC
GGCTACACCCTGGGTGACGC

Downstream 100 bases:

>100_bases
CAGAGATTTTTGCCAAAAACGCAAAAGACTTTGCACATTTTGCTAATTTCACCGCACCGCCCGTCAGCGTAGAATCAGCA
GCAAACGCATTTCTTGAGGA

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNELNAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLIALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVRW

Sequences:

>Translated_449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNELNAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLIALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVRW
>Mature_449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNELNAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLIALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVRW

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1789403, Length=449, Percent_Identity=78.8418708240534, Blast_Score=710, Evalue=0.0,
Organism=Escherichia coli, GI1790551, Length=297, Percent_Identity=33.6700336700337, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786783, Length=350, Percent_Identity=28.2857142857143, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788279, Length=283, Percent_Identity=28.2685512367491, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=30.5084745762712, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786600, Length=214, Percent_Identity=29.9065420560748, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=31.6872427983539, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=31.3559322033898, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=256, Percent_Identity=30.859375, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=29.7520661157025, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=27.681660899654, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QSEC_SALTI (Q8Z3P2)

Other databases:

- EMBL:   AL627277
- EMBL:   AE014613
- RefSeq:   NP_457571.1
- RefSeq:   NP_806783.1
- ProteinModelPortal:   Q8Z3P2
- SMR:   Q8Z3P2
- GeneID:   1067333
- GeneID:   1249621
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t3099
- KEGG:   sty:STY3355
- HOGENOM:   HBG334875
- OMA:   QTRHNIN
- ProtClustDB:   PRK10337
- BioCyc:   SENT209261:T3099-MONOMER
- BioCyc:   SENT220341:STY3355-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 50608; Mature: 50608

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x101d0aac)-; HASH(0x10e01d10)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCH
NELNAPQRMAHTPKKLKHGHIDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNG
HHCCCCHHHHCCHHHHCCCCCCCHHHEEEEEECCCEEEEECCCCCCCCCHHHHHCCCCCC
YLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIVAAQLTPWLIALPFMLLILLL
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNNLQDVAEISLEELLQSAVMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEEECHHHHHHCCHHHHHHHHHHHH
LDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHIGERFYRPPGQSVTGSGLGLS
HHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IVRRIATLHGMTVSFGNAAEGGFEAVVRW
HHHHHHHHHCCEEECCCCCCCCHHHHCCH
>Mature Secondary Structure
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCH
NELNAPQRMAHTPKKLKHGHIDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNG
HHCCCCHHHHCCHHHHCCCCCCCHHHEEEEEECCCEEEEECCCCCCCCCHHHHHCCCCCC
YLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIVAAQLTPWLIALPFMLLILLL
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNNLQDVAEISLEELLQSAVMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEEECHHHHHHCCHHHHHHHHHHHH
LDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHIGERFYRPPGQSVTGSGLGLS
HHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IVRRIATLHGMTVSFGNAAEGGFEAVVRW
HHHHHHHHHCCEEECCCCCCCCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504