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The map label for this gene is sopD [H]

Identifier: 29143201

GI number: 29143201

Start: 2921872

End: 2922825

Strand: Direct

Name: sopD [H]

Synonym: t2846

Alternate gene names: 29143201

Gene position: 2921872-2922825 (Clockwise)

Preceding gene: 29143200

Following gene: 29143205

Centisome position: 60.97

GC content: 41.93

Gene sequence:

>954_bases
ATGCCAGTCACTTTAAGCTTCGGTAATCATCAAAATTATACGCTTAATGAAAGTCGGCTTGCTCATCTGTTAAGCGCAGA
TAAAGAAAAAGCAATCCATATGGGGGGCTGGGATAAAGTCCAGGATCATTTTAGAGCGGAAAAAAAGGACCATGCGCTGG
AAGTGTTACACTCCATCATTCACGGGCAGGGCCGTGGTGAACCTGGAGAGATGGAAGTTAACGTAGAGGATATCAATAAA
ATTTACGCCTTTAAACGGCTACAACATCTGGCCTGCCCGGCTCATCAGGATCTGTTTACTATCAAGATGGACGCTTCTCA
GACACAATTTTTACTTATGGTCGGCGACACGGTGATCAGCCAAAGCAATATTAAGGACATCCTCAATATATCAGATGATG
CAGTGATAGAATCTATGAGTAGAGAAGAGAGACAGTTATTTTTACAAATATGCGAGGTGATTGGTGCGAAGATGACCTGG
CACCCGGAATTACTTCAGGAGTCGATTTCTACTCTACGAAAAGAAGTGACGGGCAATGCACAAATCAAAGCGGCGGTTTA
TGAGATGATGCGTCCCGCAGAGGCTCCAGACCACCCGCTTGTCGAATGGCAGGACTCGCTTACTGAAGATGAAAAATCGA
TGCTGGCCTGTATTAATGCCGGTAACTTTGAGCCTACAACTCAGTTTTGCAAAATAGGTTATCAGGAGGTACAAGGTGAA
GTCGCTTTTAGCATGATGCATCCGTGCATCTCCTATTTACTACATACCTATTCACCGTTTGCAGAGTTTAAACCAACAAA
TTCCGGTTTTTTAAAAAAACTTAATCAGGATTATAACGACTACCATGCAAAAAAAATGTTTATTGATGTAATTCTTGAAA
AGCTATATCTAACGCATGAACGTTCTTTGCACATTGGTAAAGATGGGTGCAGTCGTAATATATTACTGACATAA

Upstream 100 bases:

>100_bases
TCTCTCCTGTAGTAAACCTTGTCTGTTTAATAAAAAAGAGCGAATTGAACGATATATTTTACTCCGGATATTGAATAATA
TAAATTTGAAGGAAAATATT

Downstream 100 bases:

>100_bases
AGATAGCCAGTAATATAACCAATTTAAAATCCGGCTGCCTGCCGGATTTTACATAGCAGCAAGTATAATCATACCGCGTA
AGGACAATTACCCTTCATGC

Product: hypothetical protein

Products: NA

Alternate protein names: Salmonella outer protein D [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINK
IYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTW
HPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGE
VAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT

Sequences:

>Translated_317_residues
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINK
IYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTW
HPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGE
VAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>Mature_316_residues
PVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKI
YAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWH
PELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEV
AFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to replication in macrophages. Plays a role, cooperatively with sopB, in membrane fission and macropinosome formation during invasion [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cytoplasm. Host cell membrane. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into the host cell (Probable). Membrane-associated in transfected cells. Recruited to the bacterial invasion site, and

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sopD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022747
- ProDom:   PD040905 [H]

Pfam domain/function: PF11047 SopD [H]

EC number: NA

Molecular weight: Translated: 36152; Mature: 36021

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSII
CCEEEECCCCCCCEECHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVIS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCHHHH
QSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
QIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGE
HHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHE
HHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
RSLHIGKDGCSRNILLT
CCEEECCCCCCCCCCCC
>Mature Secondary Structure 
PVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSII
CEEEECCCCCCCEECHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVIS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCHHHH
QSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
QIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGE
HHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHE
HHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
RSLHIGKDGCSRNILLT
CCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2670946; 11677609 [H]